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Current Drug Discovery Technologies

Volume 16, 4 Issues, 2019
ISSN: 1875-6220 (Online)
ISSN: 1570-1638 (Print)
This journal supports open access

Aims & Scope

Due to the plethora of new approaches being used in modern drug discovery by the pharmaceutical industry, Current Drug Discovery Technologies has been established to provide comprehensive overviews of all the major modern techniques and technologies used in drug design and discovery. The journal is the forum for publishing original research papers, full-length/mini reviews, drug clinical trial studies and guest edited thematic issues describing novel approaches and cutting edge technologies used in all stages of drug discovery. The journal addresses the multidimensional challenges of drug discovery science including integration issues of the drug discovery process.

Current Drug Discovery Technologies is an essential journal for all scientists and research managers involved in drug discovery who wish to keep abreast of all the modern techniques and technologies used in drug discovery.

Current Drug Discovery Technologies

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Volume 16

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Number 2



Biography   Open Access



Review Article



Review Article

Chemistry and Pharmacological Activities of Biginelli Product- A Brief Overview

, 16(2): 127 - 134

Namy George, Asha Asokan Manakkadan, Ajish Ariyath, Surya Maniyamma, Vishnu Vijayakumar, Rajasree G. Pai and Subin Mary Zachariah*


DOI: 10.2174/1570163815666180807141922


Review Article



Review Article



Systemic Review Article



Research Article

In vitro and in silico Activity of Iridoids Against Leishmania amazonensis

, 16(2): 173 - 183

Maria Helena Vendruscolo, Gustavo Machado das Neves, Luciano Porto Kagami, Luiz Carlos Rodrigues Junior, Maria Luísa Nunes Diehl, Simone Cristina Baggio Gnoatto, Sérgio Augusto de Loreto Bordignon, Pedro Roosevelt Torres Romão, Vera Lucia Eifler-Lima and Gilsane Lino von Poser*


DOI: 10.2174/1570163814666171002102058


Research Article



Articles Ahead of Print



The Effect of Viola Odorata L. Oil for Fever in Children: A Randomized Triple-blinded Placebo-controlled Clinical Trial


Vahid Tafazoli, Mahdi Shahriari, Mojtaba Heydari, Hosein Ali Nikbakht, Mohammad Mahdi Zarshenaas and Majid Nimrouzi*


DOI: 10.2174/1570163816666190620142256
View Abstract View on PubMed




Photochemical /Photocytotoxicity Studies of New Tetrapyrrolic Structures as Potential Candidates for Cancer Theranostics


L. F. Vieira Ferreira *, I. Ferreira Machado, A. Gama, R. P. Socoteanu, R. Boscencu, G. Manda, R. C. Calhelha and I. C.F.R. Ferreira


DOI: 10.2174/1570163816666190411100919
View Abstract View on PubMed




Hybrid Design of Isonicotinic Acid Hydrazide Derivatives: Machine Learning Studies, Synthesis and Biological Evaluation of their Antituberculosis Activity


Vasyl Kovalishyn, Diana Hodyna, Vitaliy O. Sinenko, Volodymyr Blagodatny, Ivan Semenyuta, Sergiy R. Slivchuk, Volodymyr Brovarets, Gennady Poda* and Larysa Metelytsia


DOI: 10.2174/1570163816666190411110331
View Abstract View on PubMed



Abstracts Ahead of Print


Discovery and Development of Novel Anti-fungal Peptides Against Food-spoiling Fungi


Belal J. Muhialdin*, Hussein L. Algboory, Nameer K. Mohammed, Hana Kadum, Anis Shobirin Meor Hussin, Nazamid Saari and Zaiton Hassan


DOI: 10.2174/1570163816666190715120038
View Abstract





Large-scale high-throughput screening revealed 5'-(carbonylamino)-2,3'-bithiophene-4'-carboxylate as novel template for antibacterial agents


Yan A. Ivanenkov, Renat S. Yamidanov, Ilya A. Osterman, Petr V. Sergiev, Vladimir A. Aladinskiy, Anastasia V. Aladinskaya, Victor A. Terentiev, Mark S. Veselov, Andrey A. Ayginin, Dmitry A. Skvortsov, Katerina S. Komarova, Bogdan A. Zagribelnyy*, Alexey Kh. Baimiev, Kseniya Yu. Shvetc, Andrey Kh. Baimiev, Alina A. Sofronova, Alexey E. Machulkin, Rostislav A. Petrov, Liana F. Zainullina, Marina A. Maximova, Zulfiya R. Zileeva, Yulia V. Vakhitova, Dmitry S. Bezrukov, Maria M. Puchinina and Olga A. Dontsova


DOI: 10.2174/1570163816666190603095521
View Abstract




Published Contents

Editor's Choice



Molecular Docking, Synthesis and Biological Evaluation of Sulphonylureas/ Guanidine Derivatives as Promising Antidiabetic Agent

, 2018; 15(4): 315 - 325

Ishan I. Panchal*, Dhrubo Jyoti Sen, Ashish D. Patel, Umang Shah, Mehul Patel, Archana Navale and Vashisth Bhavsar


DOI: 10.2174/1570163814666171002102904





Affinity Crystallography Reveals the Bioactive Compounds of Industrial Juicing Byproducts of Punica granatum for Glycogen Phosphorylase

, 2018; 15(1): 41 - 53

George A. Stravodimos, Anastassia L. Kantsadi, Anna Apostolou, Efthimios Kyriakis, Vassiliki-Nafsika Kafaski-Kanelli, Theodora Solovou, Pagona Gatzona, Panagiota G.V. Liggri, Stavroula Theofanous, Vyron A. Gorgogietas, Apostolia Kissa, Chariklia Psachoula, Angelos Lemonakis, Demetra S.M. Chatzileontiadou, Anna-Maria G. Psarra, Vassiliki T. Skamnaki, Serkos A. Haroutounian* and Demetres. D. Leonidas*


DOI: 10.2174/1570163814666170619091736






QSAR Studies, Synthesis and Antibacterial Assessment of New Inhibitors Against Multidrug-Resistant Mycobacterium tuberculosis

, 2017; 14(1): 25 - 38

Vasyl Kovalishyn, Volodymyr Brovarets, Volodymyr Blagodatnyi, Iryna Kopernyk, Diana Hodyna, Svitlana Chumachenko, Oleg Shablykin, Oleksandr Kozachenko, Myhailo Vovk, Marianna Barus, Myhailo Bratenko and Larysa Metelytsia


DOI: 10.2174/1570163813666161108125227



Open Access Articles

The Modulatory Effect of Lead Drug Candidates on Inflammatory Gene Expression in Sepsis: A Mini-Review

, 2019; 16(1): 48 - 56

Samuel Mawuli Adadey*, Michael Bright Yakass, Seth Agyemang and Samuel Duodu




Date Palm (Phoenix dactylifera): Novel Findings and Future Directions for Food and Drug Discovery

, 2019; 16(1): 2 - 10

Ali H. El-Far*, Babatunji E. Oyinloye, Masood Sepehrimanesh, Mahmoud A. Gab Allah, Ibrahim Abu-Reidah, Hazem M. Shaheen, Iman Razeghian-Jahromi, Abd el-wahab A. Alsenosy, Ahmed E. Noreldin, Soad K. Al Jaouni and Shaker A. Mousa*




The Development of New Factor Xa Inhibitors Based on Amide Synthesis

, 2018; 15(4): 335 - 350

Dmitry N. Tarasov, Dmitry G. Tovbin, Dmitry V. Malakhov, Arseniy V. Aybush, Natalia A. Tserkovnikova, Marina I. Savelyeva, Dmitry A. Sychev, Natalia N. Drozd* and Alla Y. Savchenko




Structure-Based Docking Studies of GLUT4 Towards Exploring Selected Phytochemicals from Solanum xanthocarpum as a Therapeutic Target for the Treatment of Cancer

, 2018; 15: 1 - 10 (E-Pub Ahead of Print)

Babatunji Emmanuel Oyinloye*, Tayo Alex Adekiya, Raphael Taiwo Aruleba, Oluwafemi Adeleke Ojo and Basiru Olaitan Ajiboye






Can EGFR-Tyrosine Kinase Inhibitors (TKI) Alone Without Talc Pleurodesis Prevent Recurrence of Malignant Pleural Effusion (MPE) in Lung Adenocarcinoma

, 2016; 13(2): 68 - 76

Akash Verma, Akhil Chopra, Yeo W. Lee, Lavina D. Bharwani, Atasha B. Asmat, Dokeu B.A Aneez, Fazuludeen A. Akbar, Albert Y.H. Lim, Sanjay H. Chotirmall and John Abisheganaden




Quantitative Structure-Cytotoxic Activity Relationship 1-(Benzoyloxy)urea and Its Derivative

, 2016; 13(2): 101 - 108

Suko Hardjono, Siswandono Siswodihardjo, Purwanto Pramono and Win Darmanto









Most Cited Articles

Review Article

Update on nitazoxanide: A multifunctional chemotherapeutic agent

, 2018; 15(3): 201-213.

Anshul Shakya*, Hans Raj Bhat and Surajit Kumar Ghosh


DOI: 10.2174/1570163814666170727130003


Research Article

Immunomodulatory effect of G2013 (α-L-guluronic acid) on the TLR2 and TLR4 in human mononuclear cells

, 2018; 15(2): 123-131.

Laleh Sharifi, Monireh Mohsenzadegan, Asghar Aghamohammadi*, Nima Rezaei, Farzaneh Tofighi Zavareh, Saied Bokaie, Mona Moshiri, Zahra Aghazadeh, Zahra Norouzbabaie, Gholamreza Azizi and Abbas Mirshafiey*


DOI: 10.2174/1570163814666170605111331



Review Article

Thiazole containing heterocycles with CNS activity

, 2018; 15(3): 178-195.

Shikha Agarwal*, Priyanka Kalal, Divyani Gandhi and Prakash Prajapat


DOI: 10.2174/1570163814666170724170152


Review Article

A retrospect study on thiazole derivatives as the potential antidiabetic agents in drug discovery and developments

, 2018; 15(3): 163-177.

Gopal L. Khatik*, Ashok Kumar Datusalia, Waquar Ahsan, Paranjeet Kaur, Manish Vyas, Amit Mittal and Surendra Kumar Nayak


DOI: 10.2174/1570163814666170915134018


Review Article

Multifaceted effects of delta opioid receptors and dadle in diseases of the nervous system

, 2018; 15(2): 94-108.

Jea-Young Lee, M. Grant Liska, Marci Crowley, Kaya Xu, Sandra A. Acosta, Cesar V. Borlongan* and Vivian A. Guedes


DOI: 10.2174/1570163814666171010114403


Review Article

Anti-carcinogenic effects of carnosol-an updated review

, 2018; 15(1): 32-40.

Saeed Samarghandian, Mohsen Azimi-Nezhad and Tahereh Farkhondeh*


DOI: 10.2174/1570163814666170413121732


Review Article

Review on synthetic chemistry and antibacterial importance of thiazole derivatives

, 2018; 15(3): 214-228.

Ankita Kashyap, Nayana Adhikari, Arpita Das, Anshul Shakya, Surajit Kumar Ghosh, Udaya Pratap Singh and Hans Raj Bhat*


DOI: 10.2174/1570163814666170911144036




Research Article

In vitro and in vivo assessment of silver nanoparticles against clostridium botulinum type a botulinum

, 2019; 16(1): 113-119.

Mohammad Aminianfar, Siavash Parvardeh and Mohsen Soleimani*


DOI: 10.2174/1570163815666180403163946


Review Article

An evidence-based review of medicinal herbs for the treatment of gastroesophageal reflux disease (GERD)

, 2018; 15(4): 305-314.

Ayda Hosseinkhani, Kamran Bagheri Lankarani, Abdolali Mohagheghzadeh, Chunlin Long and Mehdi Pasalar*


DOI: 10.2174/1570163814666171010113517


General Review Article

Toxicity of biologically active peptides and future safety aspects: An update

, 2018; 15(3): 236-242.

Fazlullah Khan, Kamal Niaz and Mohammad Abdollahi*


DOI: 10.2174/1570163815666180219112806


General Review Article

Effectiveness of Cicer arietinum in cutaneous problems: Viewpoint of Avicenna and Razi

, 2018; 15(3): 243-250.

Marjan Mahjour, Arash Khoushabi, MohammadReza Noras and Shokouhsadat Hamedi*


DOI: 10.2174/1570163814666170829142752




Most Accessed Articles


Molecular Docking in Formulation and Development

, 2019; 16(1): 30-39.

Tejinder Kaur*, Ashwini Madgulkar, Mangesh Bhalekar and Kalyani Asgaonkar


DOI: 10.2174/1570163815666180219112421




Date Palm (Phoenix dactylifera): Novel Findings and Future Directions for Food and Drug Discovery

, 2019; 16(1): 2-10.

Ali H. El-Far*, Babatunji E. Oyinloye, Masood Sepehrimanesh, Mahmoud A. Gab Allah, Ibrahim Abu-Reidah, Hazem M. Shaheen, Iman Razeghian-Jahromi, Abd el-wahab A. Alsenosy, Ahmed E. Noreldin, Soad K. Al Jaouni and Shaker A. Mousa*


DOI: 10.2174/1570163815666180320111937


Compound Libraries: Recent Advances and Their Applications in Drug Discovery

, 2017; 14(4): 216-228.

Zhen Gong, Guoping Hu, Qiang Li, Zhiguo Liu, Fei Wang, Xuejin Zhang, Jian Xiong, Peng Li, Yan Xu, Rujian Ma, Shuhui Chen and Jian Li*


DOI: 10.2174/1570163814666170425155154



Molecular Docking, Synthesis and Biological Evaluation of Sulphonylureas/ Guanidine Derivatives as Promising Antidiabetic Agent

, 2018; 15(4): 315-325.

Ishan I. Panchal*, Dhrubo Jyoti Sen, Ashish D. Patel, Umang Shah, Mehul Patel, Archana Navale and Vashisth Bhavsar


DOI: 10.2174/1570163814666171002102904






Editor-in-Chief

Vladimir P. Torchilin
(44972 citations)
Department of Pharmaceutical Science Center for Pharmaceutical Biotechnology and Nanomedicine
Northeastern University
Boston, MA 02115
USA

Biography View Full Editorial Board

Journal History

Current Drug Discovery Technologies Journal was launched in 2004. Dr. Vladimir P. Torchilin serves as the Editor-in-Chief of the journal.
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