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Current Chemical Biology

Volume 15, 4 Issues, 2021
ISSN: 1872-3136 (Online)
ISSN: 2212-7968 (Print)
This journal supports open access

Aims & Scope

Current Chemical Biology aims to publish full-length and mini reviews as well as research papers on exciting new developments at the chemistry-biology interface, covering topics relating to Chemical Synthesis, Science at Chemistry-Biology Interface and Chemical Mechanisms of Biological Systems.

Current Chemical Biology covers the following areas: Chemical Synthesis (Syntheses of biologically important macromolecules including proteins, polypeptides, oligonucleotides, oligosaccharides etc.; Asymmetric synthesis; Combinatorial synthesis; Diversity-oriented synthesis; Template-directed synthesis; Biomimetic synthesis; Solid phase biomolecular synthesis; Synthesis of small biomolecules: amino acids, peptides, lipids, carbohydrates and nucleosides; and Natural product synthesis).

Science at Chemistry-Biology Interface (Chemical informatics; Macromolecular catalysts and receptors; Enzymatic synthesis; Biosynthetic engineering; Combinatorial biosynthesis; Plant cell based chemistry; Bacterial and viral cell based chemistry; Chemistry of cellular processes in plants/animals; Receptor chemistry; Cell signaling chemistry; Drug design through understanding of disease processes; Synthetic biology; New high throughput screening techniques; Small molecular array fabrication; Chemical genomics; Chemical and biological approaches to carbohydrates proteins and nucleic acids design; Chemical and biological regulation of biosynthetic pathways; and Unnatural biomolecular analogs).

Chemical Mechanisms of Biological Systems (Mechanisms of drug design; Molecular recognition; Enzyme inhibition mechanisms; Chemical mechanisms of biological functions; Molecular machines; Chemical ecology; Metal ions in biological systems; Metalloenzymes; Chemical mechanisms, proteomics and metabonomics; Chemical imaging; Small molecule-biological target interactions; Biologically active natural products; Elucidation of biosynthetic pathways; and Simulation and modeling of biomolecules).

Current Chemical Biology

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Volume 15

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Number 2





Review Article (Mini-Review)



Review Article

Cyclin-Dependent Kinase as a Novel Therapeutic Target: An Endless Story

, 15(2): 139 - 162

Ahmed Mohamed Etman, Sherif Sabry Abdel Mageed, Mohamed Ahmed Ali and Mahmoud Abd El Monem El Hassab*


DOI: 10.2174/2212796814999201123194016








Research Article

Anticarcinogenic Effects of Capsaicin-Loaded Nanoparticles on In vitro Hepatocellular Carcinoma

, 15(2): 188 - 201

Noha M Hazem*, Wagdi F ElKashef, Ibrahim M El-Sherbiny, Ahmed A Emam, Dalia Shaalan and Mohamed Sobh


DOI: 10.2174/2212796814999201116211648


Open Access Articles

Dose Formulation, Biodistribution and PET Imaging Studies of a First-in-Class Fluorine-18 Organophosphorus Cholinesterase Inhibitor Tracer in Rat

, 2020; 14(4): 289 - 303

Kiel D. Neumann, Joseph E. Blecha, Chih-Kai Chao, Tony Huynh, Kurt R. Zinn, Henry F. VanBrocklin, Charles M. Thompson and John M. Gerdes*




Docking Simulations Exhibit Bortezomib and other Boron-containing Peptidomimetics as Potential Inhibitors of SARS-CoV-2 Main Protease

, 2020; 14(4): 279 - 288

Iván R Vega-Valdez, Rosalez Melvin N., Santiago-Quintana José M., Farfán-García Eunice D. and Soriano-Ursúa Marvin A.*




Hsp90 as Drug Target Against Bacterial and Fungal Infections

, 2020; 14(3): 153 - 168

Mohammad W. Islam, Samir H. Bloukh, Zehra Edis* and Sabrina A. Gacem




POCl3 Mediated Syntheses, Pharmacological Evaluation and Molecular Docking Studies of Some Novel Benzofused Thiazole Derivatives as a Potential Antioxidant and Anti-inflammatory Agents

, 2020; 14(1): 58 - 68

Dattatraya G. Raut*, Sandeep B. Patil, Prafulla B. Choudhari, Vikas D. Kadu, Anjana S. Lawand, Mahesh G. Hublikar and Raghunath B. Bhosale





Cytotoxicity Evaluation of Dimethoxy and Trimethoxy Indanonic Spiroisoxazolines Against Cancerous Liver Cells

, 2020; 14(1): 38 - 47

Ahmad Abolhasani , Fatemeh Heidari , Somayeh Noori, Shokoufeh Mousavi and Hoda Abolhasani *










Functional Characterization of Chitin and Chitosan

, 2009; 3(2): 203 - 230

Inmaculada Aranaz, Marian Mengibar, Ruth Harris, Ines Panos, Beatriz Miralles, Niuris Acosta, Gemma Galed and Angeles Heras




Cause of Chirality Consensus

, 2008; 2(2): 153 - 158

Salla Jaakkola, Vivek Sharma and Arto Annila






Most Cited Articles

Review Article

Endogenous repair system of oxidative damage of DNA

, 2019; 13(2): 110-119.

Anmol Sharma, Pawan Gupta and Pranav Kumar Prabhakar*


DOI: 10.2174/2212796813666190221152908



Research Article

RNAi-mediated resistance against plant parasitic nematodes of wheat plants obtained in vitro using bioregulators of microbiological origin

, 2019; 13(1): 73-89.

Victoria A. Tsygankova *, Yaroslav V. Andrusevich, Elena N. Shysha, Lyudmila O. Biliavska, Tatyana O. Galagan, Anatoly P. Galkin, Alla I. Yemets , Galina A. Iutynska and Yaroslav B. Blume


DOI: 10.2174/2212796812666180507130017



Research Article

Antimicrobial activity of highly fluorinated thiocarbamates and dithiocarbamates

, 2019; 13(2): 120-128.

Amal Thebti, Ines Chniti, Med Abderrahmane Sanhoury*, Ikram Chehidi, Hadda Imene Ouzari and Abdellatif Boudabous


DOI: 10.2174/2212796812666180907153901


Review Article

A recent review on drug modification using 1,2,3-triazole

, 2020; 14(2): 71-87.

Adarsh Sahu*, Preeti Sahu and Ramkishore Agrawal


DOI: 10.2174/2212796814999200807214519


Research Article

Bioremediation of simulated textile effluent by an efficient bio-catalyst purified from a novel pseudomonas fluorescence lip-rl5

, 2020; 14(2): 128-139.

Ranju K. Rathour, Vaishali Sharma, Nidhi Rana, Ravi K. Bhatia and Arvind K. Bhatt*


DOI: 10.2174/2212796814666200406100247



Research Article

Cytotoxicity evaluation of dimethoxy and trimethoxy indanonic spiroisoxazolines against cancerous liver cells

, 2020; 14(1): 38-47.

Ahmad Abolhasani , Fatemeh Heidari , Somayeh Noori, Shokoufeh Mousavi and Hoda Abolhasani *


DOI: 10.2174/2212796813666190926112807


Research Article

In-vitro and in-silico characterization of xylose reductase from Emericella nidulans

, 2019; 13(2): 159-170.

Vishal Ahuja*, Aashima Sharma, Ranju Kumari Rathour, Vaishali Sharma, Nidhi Rana and Arvind Kumar Bhatt


DOI: 10.2174/2212796812666180622103906



Research Article

Docking simulations exhibit bortezomib and other boron-con-taining peptidomimetics as potential inhibitors of sars-cov-2 main protease

, 2020; 14(4): 279-288.

Iván R Vega-Valdez, Rosalez Melvin N., Santiago-Quintana José M., Farfán-García Eunice D. and Soriano-Ursúa Marvin A.*


DOI: 10.2174/2212796814999201102195651


Review Article

Peaceful existence of tumor cells with their non-malignant neighbors: The trade of tumor cells with tumor micro-environment

, 2020; 14(4): 228-239.

Amirhosein Maali, Mohammad Sarfi, Mohammad Mirzakhani, Golnaz Goodarzi, Hosein Maghsoudi, Mahmood Maniati, Sadra Samavarchi Tehrani* and Durdi Qujeq*


DOI: 10.2174/2212796814999200925162943


Research Article

Safety evaluation of eucalyptus globulus essential oils through acute and sub-acute toxicity and skin irritation in mice and rats

, 2020; 14(3): 187-195.

Berhan Mengiste, Tizazu Zenebe*, Kassahun Dires, Ermias Lulekal, Awol Mekonnen, Nigus Zegeye and Yoseph Shiferaw


DOI: 10.2174/2212796814999200818095036


Research Article

Insight on ameliorative role of selenium nanoparticles and niacin in wound healing on adult female albino mice

, 2020; 14(3): 169-186.

Marwa Emam, Akaber T. Keshta, Yasser M.A. Mohamed and Yasser A. Attia*


DOI: 10.2174/2212796814666200818111849



Most Accessed Articles

Serum Biomarkers for Noninvasive Diagnosis of Liver Diseases: How Laudable are These Tools?

, 2021; 15(2): 128-138.

Ankita Singh, Vipul Ranjan, Rina Das*, Karun Bhatti, Dinesh Kumar Mehta and Ram Mohan Chidurala


DOI: 10.2174/2212796814999201111204639



Anticarcinogenic Effects of Capsaicin-Loaded Nanoparticles on In vitro Hepatocellular Carcinoma

, 2021; 15(2): 188-201.

Noha M Hazem*, Wagdi F ElKashef, Ibrahim M El-Sherbiny, Ahmed A Emam, Dalia Shaalan and Mohamed Sobh


DOI: 10.2174/2212796814999201116211648


Cyclin-Dependent Kinase as a Novel Therapeutic Target: An Endless Story

, 2021; 15(2): 139-162.

Ahmed Mohamed Etman, Sherif Sabry Abdel Mageed, Mohamed Ahmed Ali and Mahmoud Abd El Monem El Hassab*


DOI: 10.2174/2212796814999201123194016




Targeting Protein Degradation in Cancer Treatment

, 2021; 15(1): 5-18.

Imane Bjij, Ismail Hdoufane, Mahmoud Soliman, Menče Najdoska-Bogdanov and Driss Cherqaoui*


DOI: 10.2174/2212796814999200609131623




Molecular Processes Involved in Pancreatic Cancer and Therapeutics

, 2021; 15(1): 85-108.

Subhajit Makar, Abhrajyoti Ghosh, Divya, Shalini Shivhare, Ashok Kumar and Sushil K. Singh*


DOI: 10.2174/2212796814999201008130819


Ovarian Cancer Biomarkers: Headway Towards Early Diagnosis

, 2021; 15(1): 109-125.

Zeba Mueed, Pankaj Kumar Rai, Seemab Siddique and Nitesh Kumar Poddar*


DOI: 10.2174/2212796815666210121095445



Docking Simulations Exhibit Bortezomib and other Boron-containing Peptidomimetics as Potential Inhibitors of SARS-CoV-2 Main Protease

, 2020; 14(4): 279-288.

Iván R Vega-Valdez, Rosalez Melvin N., Santiago-Quintana José M., Farfán-García Eunice D. and Soriano-Ursúa Marvin A.*


DOI: 10.2174/2212796814999201102195651



Peaceful Existence of Tumor Cells with Their Non-malignant Neighbors: The Trade of Tumor Cells with Tumor Microenvironment

, 2020; 14(4): 228-239.

Amirhosein Maali, Mohammad Sarfi, Mohammad Mirzakhani, Golnaz Goodarzi, Hosein Maghsoudi, Mahmood Maniati, Sadra Samavarchi Tehrani* and Durdi Qujeq*


DOI: 10.2174/2212796814999200925162943




Editor-in-Chief

graphic
Claudio Santi
Department of Pharmaceutical Sciences
University of Perugia
Perugia
(Italy)
Biography
View Full Editorial Board

Journal History

Current Chemical Biology was launched in 2007. Dr. Claudio Santi serves as the Editor-in-Chief of the journal.

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