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Current Alzheimer Research

Volume 18, 14 Issues, 2021
ISSN: 1875-5828 (Online)
ISSN: 1567-2050 (Print)
This journal supports open access

Aims & Scope

Current Alzheimer Research publishes peer-reviewed frontier review, research, drug clinical trial studies and letter articles on all areas of Alzheimer’s disease. This multidisciplinary journal will help in understanding the neurobiology, genetics, pathogenesis, and treatment strategies of Alzheimer’s disease. The journal publishes objective reviews written by experts and leaders actively engaged in research using cellular, molecular, and animal models. The journal also covers original articles on recent research in fast emerging areas of molecular diagnostics, brain imaging, drug development and discovery, and clinical aspects of Alzheimer’s disease. Manuscripts are encouraged that relate to the synergistic mechanism of Alzheimer's disease with other dementia and neurodegenerative disorders. Book reviews, meeting reports and letters-to-the-editor are also published. The journal is essential reading for researchers, educators and physicians with interest in age-related dementia and Alzheimer’s disease. Current Alzheimer Research provides a comprehensive 'bird's-eye view' of the current state of Alzheimer's research for neuroscientists, clinicians, health science planners, granting, caregivers and families of this devastating disease.

Current Alzheimer Research

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Volume 18

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Number 1



Research Article   Open Access

Clinical Application of the Vestibular Stimulation Effect on Balance Disorders with Dementia

, 18(1): e242403032121192426

Kiyotaka Nakamagoe*, Shiori Yamada, Rio Kawakami, Takami Maeno, Tadachika Koganezawa and Akira Tamaoka


DOI: 10.2174/1567205018666210324105642




Research Article   Open Access

APP/PS1 Gene-Environment Noise Interaction Aggravates AD-like Neuropathology in Hippocampus Via Activation of the VDAC1 Positive Feedback Loop

, 18(1): e242403032121192430

Huimin Chi, Qingfeng Zhai, Ming Zhang, Donghong Su, Wa Cao, Wenlong Li, Xiaojun She, Honglian Yang, Kun Wang, Xiujie Gao, Kefeng Ma, Bo Cui* and Yugang Qiu*


DOI: 10.2174/1567205018666210324114153


Research Article

In Vivo/Ex Vivo EPR Investigation of the Brain Redox Status and Blood-Brain Barrier Integrity in the 5xFAD Mouse Model of Alzheimer's Disease

, 18(1): e242403032121192434

Ana Vesković, Đura Nakarada, Aleksandra Pavićević, Bogomir Prokić, Milka Perović, Selma Kanazir, Ana Popović-Bijelić* and Miloš Mojović


DOI: 10.2174/1567205018666210324121156


Research Article

Disrupted White Matter Networks from Subjective Memory Impairment to Amnestic Mild Cognitive Impairment

, 18(1): e242403032121192433

Wen Shao, Xuwen He, Xin Li, Wuhai Tao, Junying Zhang, Shujuan Zhang, Lei Wang, Yanan Qiao, Yu Wang, Zhanjun Zhang* and Dantao Peng*


DOI: 10.2174/1567205018666210324115817


Research Article

An Effective Brain Imaging Biomarker for AD and aMCI: ALFF in Slow-5 Frequency Band

, 18(1): e242403032121192438

Luoyu Wang, Qi Feng, Mei Wang, Tingting Zhu, Enyan Yu, Jialing Niu, Xiuhong Ge, Dewang Mao, Yating Lv* and Zhongxiang Ding*


DOI: 10.2174/1567205018666210324130502


Research Article

Effects of Gene and Plasma Tau on Cognitive Impairment in Rural Chinese Population

, 18(1): e242403032121192435

Xu Tang, Shuzhen Liu, Jiansheng Cai, Quanhui Chen, Xia Xu, Chun B. Mo, Min Xu, Tingyu Mai, Shengle Li, Haoyu He, Jian Qin* and Zhiyong Zhang*


DOI: 10.2174/1567205018666210324122840


Research Article

Apolipoprotein E Gene Revisited: Contribution of Rare Variants to Alzheimer’s Disease Susceptibility in Southern Chinese

, 18(1): e242403032121192427

Anita Yee, Nancy B.Y. Tsui, Rick Y.C. Kwan, Angela Y.M. Leung, Claudia K.Y. Lai, Teresa Chung, Johnson Y.N. Lau, Manson Fok, David L.K. Dai* and Lok-Ting Lau*


DOI: 10.2174/1567205018666210324111401


Articles Ahead of Print

There are currently no Articles Ahead of Print available for this journal.

Abstracts Ahead of Print



Development and Validation of a Model to Identify Alzheimer’s Disease and Related Syndromes in Administrative Data


A Gallini, D Jegou, M Lapeyre-Mestre, A Couret, R Bourrel, P-J Ousset, D Fabre, S Andrieu and V Gardette*


DOI: 10.2174/1567205018666210416094639
View Abstract




Weight Loss and the Risk of Dementia: A Meta-analysis of Cohort Studies


Chao Wang, Wenning Fu, Shiyi Cao, Heng Jiang, Yingying Guo, Hongbin Xv, Jianxin Liu, Yong Gan* and Zuxun Lu*


DOI: 10.2174/1567205018666210414112723
View Abstract


PET/MRI Delivers Multimodal Brain Signature in Alzheimer’s Disease with De Novo PSEN1 Mutation


Gayane Aghakhanyan, Dorothee Saur, Michael Rullmann, Christopher M. Weise, Matthias L. Schroeter, Ken Marek, Rami Abou Jamra, Solveig Tiepolt, Maria Strauss, Cordula Scherlach, Karl-Titus Hoffmann, Osama Sabri, Joseph Classen and Henryk Barthel*


DOI: 10.2174/1567205018666210414111536
View Abstract


Cerebrospinal fluid inflammatory markers in Alzheimer’s disease: influence of comorbidities


Ying Wang*, Ceren Emre, Helena Gyllenhammar-Schill, Karin Fjellman, Helga Eyjolfsdottir, Maria Eriksdotter, Marianne Schultzberg and Erik Hjorth*


DOI: 10.2174/1567205018666210330162207
View Abstract


Published Contents

Editor's Choice

Clinical Application of the Vestibular Stimulation Effect on Balance Disorders with Dementia

, 2021; 18(1): 1 - 7

Kiyotaka Nakamagoe*, Shiori Yamada, Rio Kawakami, Takami Maeno, Tadachika Koganezawa and Akira Tamaoka


DOI: 10.2174/1567205018666210324105642



APP/PS1 Gene-Environment Noise Interaction Aggravates AD-like Neuropathology in Hippocampus Via Activation of the VDAC1 Positive Feedback Loop

, 2021; 18(1): 14 - 24

Huimin Chi, Qingfeng Zhai, Ming Zhang, Donghong Su, Wa Cao, Wenlong Li, Xiaojun She, Honglian Yang, Kun Wang, Xiujie Gao, Kefeng Ma, Bo Cui* and Yugang Qiu*


DOI: 10.2174/1567205018666210324114153



Nanoparticle-Encapsulated Bryostatin-1 Activates α-Secretase and PKC Isoforms In vitro and Facilitates Acquisition and Retention of Spatial Learning in an Alzheimer's Disease Mouse Model

, 2020; 17(14): 1302 - 1310

Lisa Schrott, Ping Yi, Kasey Jackson, Gabriel S. Jackson, Christopher Webb, Alireza Minagar, J. Winny Yun, Geoffrey Purdum, David J. Rios, Theodore A. Tyler, Maria I. Vizcanio, Judith L. Castor, Trevor Castor and Jonathan S. Alexander*


DOI: 10.2174/1567205018666210218155835




Diagnosis of Mild Cognitive Impairment Using Cognitive Tasks: A Functional Near-Infrared Spectroscopy Study

, 2020; 17(13): 1145 - 1160

So-Hyeon Yoo, Seong-Woo Woo, Myung-Jun Shin, Jin A. Yoon, Yong-Il Shin and Keum-Shik Hong*


DOI: 10.2174/1567205018666210212154941








Open Access Articles


Cerebrospinal Fluid and Blood CX3CL1 as a Potential Biomarker in Early Diagnosis and Prognosis of Dementia

, 2020; 17(8): 709 - 721

Agnieszka Kulczyńska-Przybik*, Agnieszka Słowik, Piotr Mroczko, Bartłomiej Borawski, Magdalena Groblewska, Renata Borawska and Barbara Mroczko




Presenilin 1 and APP Gene Mutations in Early-Onset AD Families from a Southeast Region of China

, 2020; 17(6): 540 - 546

Jiajia Zhou, Yi Chen, Fanxia Meng, Kan Zhang, Xiaoyan Liu and Guoping Peng*




The Parietal Atrophy Score on Brain Magnetic Resonance Imaging is a Reliable Visual Scale

, 2020; 17(6): 534 - 539

David Silhan, Ales Bartos*, Jana Mrzilkova, Olga Pashkovska, Ibrahim Ibrahim and Jaroslav Tintera





Mechanisms of Anticholinesterase Interference with Tau Aggregation Inhibitor Activity in a Tau-Transgenic Mouse Model

, 2020; 17(3): 285 - 296

Gernot Riedel , Jochen Klein , Grazyna Niewiadomska, Constantin Kondak , Karima Schwab , Dilyara Lauer , Mandy Magbagbeolu , Marta Steczkowska, Maciej Zadrozny , Malgorzata Wydrych , Anna Cranston , Valeria Melis, Renato X. Santos , Franz Theuring , Charles R. Harrington and Claude M. Wischik*




Dangerous Liaisons: Tau Interaction with Muscarinic Receptors

, 2020; 17(3): 224 - 237

Adrianna Wysocka, Ewelina Palasz, Marta Steczkowska and Grazyna Niewiadomska*




Association Between Anemia and Dementia: A Nationwide, Populationbased Cohort Study in Taiwan

, 2020; 17(2): 196 - 204

Chien-Tai Hong, Yi-Chen Hsieh, Hung-Yi Liu, Hung-Yi Chiou and Li-Nien Chien*




Joint Effect of ABCA7 rs4147929 and Body Mass Index on Progression from Mild Cognitive Impairment to Alzheimer’s Disease: The Shanghai Aging Study

, 2020; 17(2): 185 - 195

Jianxiong Xi, Ding Ding*, Qianhua Zhao, Xiaoniu Liang, Li Zheng, Qihao Guo, Zhen Hong, Hua Fu, Jianfeng Xu and Qianyi Xiao*




Intracranial Atherosclerotic Stenosis is Related to Post-stroke Cognitive Impairment: A Cross-sectional Study of Minor Stroke

, 2020; 17(2): 177 - 184

Li Gong, Haichao Wang, Qiong Dong, Xiaoping Zhu, Xiaoran Zheng, Yongzhe Gu, Wangli Cai, Yanxin Zhao* and Xueyuan Liu*




Automatic Detection of Cognitive Impairments through Acoustic Analysis of Speech

, 2020; 17(1): 60 - 68

Ryosuke Nagumo*, Yaming Zhang, Yuki Ogawa, Mitsuharu Hosokawa, Kengo Abe, Takaaki Ukeda, Sadayuki Sumi, Satoshi Kurita, Sho Nakakubo, Sangyoon Lee, Takehiko Doi and Hiroyuki Shimada




Tau PET Distributional Pattern in AD Patients with Visuospatial Dysfunction

, 2019; 16(11): 1055 - 1062

Xi Sun, Binbin Nie, Shujun Zhao, Qian Chen, Panlong Li, Tianhao Zhang, Tingting Pan, Ting Feng, Luying Wang, Xiaolong Yin, Wei Zhang, Shilun Zhao, Baoci Shan, Hua Liu*, Shengxiang Liang*, Lin Ai* and Guihong Wang*








Most Cited Articles

Systematic Review Article

Depression in dementia or dementia in depression? Systematic review of studies and hypotheses

, 2020; 17(1): 16-28.

Agnieszka Brzezińska, Julius Bourke, Rayito Rivera-Hernández, Magda Tsolaki, Joanna Wożniak and Jakub Każmierski*


DOI: 10.2174/1567205017666200217104114


Review Article

Learning from the past: A review of clinical trials targeting amyloid, tau and neuroinflammation in Alzheimer’s disease

, 2020; 17(2): 112-125.

Kelly Ceyzériat, Thomas Zilli, Philippe Millet, Giovanni B. Frisoni, Valentina Garibotto and Benjamin B. Tournier*


DOI: 10.2174/1567205017666200304085513


Review Article

Genetic variants and oxidative stress in alzheimer’s disease

, 2020; 17(3): 208-223.

Marta Kowalska*, Katarzyna Wize, Michał Prendecki, Margarita Lianeri, Wojciech Kozubski and Jolanta Dorszewska


DOI: 10.2174/1567205017666200224121447


Research Article

Mechanisms of anticholinesterase interference with tau aggregation inhibitor activity in a tau-transgenic mouse model

, 2020; 17(3): 285-296.

Gernot Riedel , Jochen Klein , Grazyna Niewiadomska, Constantin Kondak , Karima Schwab , Dilyara Lauer , Mandy Magbagbeolu , Marta Steczkowska, Maciej Zadrozny , Malgorzata Wydrych , Anna Cranston , Valeria Melis, Renato X. Santos , Franz Theuring , Charles R. Harrington and Claude M. Wischik*


DOI: 10.2174/1567205017666200224120926


Research Article

Automatic detection of cognitive impairments through acoustic analysis of speech

, 2020; 17(1): 60-68.

Ryosuke Nagumo*, Yaming Zhang, Yuki Ogawa, Mitsuharu Hosokawa, Kengo Abe, Takaaki Ukeda, Sadayuki Sumi, Satoshi Kurita, Sho Nakakubo, Sangyoon Lee, Takehiko Doi and Hiroyuki Shimada


DOI: 10.2174/1567205017666200213094513



Review Article

Risk reduction and prevention of alzheimer's disease: Biological mechanisms of diet

, 2020; 17(5): 407-427.

Hugo McGurran, Jordan Glenn, Erica Madero and Nick Bott*


DOI: 10.2174/1567205017666200624200651


Review Article

Reversal of calcium dysregulation as potential approach for treating alzheimer's disease

, 2020; 17(4): 344-354.

Elena Popugaeva, Daria Chernyuk and Ilya Bezprozvanny*


DOI: 10.2174/1567205017666200528162046


Review Article

Microglia in Alzheimer’s disease

, 2020; 17(1): 29-43.

Patrick Süß and Johannes C.M. Schlachetzki*


DOI: 10.2174/1567205017666200212155234



General Research Article

Salivary aβ secretion and altered oral microbiome in mouse models of ad

, 2020; 17(12): 1133-1144.

Angela M. Floden, Mona Sohrabi, Suba Nookala, Jay J. Cao and Colin K. Combs *


DOI: 10.2174/1567205018666210119151952


Research Article

The association between TNF-alpha, IL-1 alpha and il-10 with alzheimer's disease

, 2020; 17(11): 972-984.

Marija Culjak, Matea N. Perkovic, Suzana Uzun, Dubravka S. Strac, Gordana N. Erjavec, Mirjana B. Leko, Goran Simic, Lucija Tudor, Marcela Konjevod, Oliver Kozumplik, Ninoslav Mimica and Nela Pivac*


DOI: 10.2174/1567205017666201130092427


Review Article

Non-steroidal anti-inflammatory drugs as candidates for the prevention or treatment of alzheimer’s disease: Do they still have a role?

, 2020; 17(11): 1013-1022.

Alberto Villarejo-Galende*, Marta González-Sánchez, Víctor A. Blanco-Palmero, Sara Llamas-Velasco and Julián Benito-León


DOI: 10.2174/1567205017666201127163018



Research Article

Exploring shared pathogenesis of alzheimer’s disease and type 2 diabetes mellitus via co-expression networks analysis

, 2020; 17(6): 566-575.

Yukun Zhu, Xuelu Ding, Zhaoyuan She, Xue Bai, Ziyang Nie, Feng Wang, Fei Wang and Xin Geng*


DOI: 10.2174/1567205017666200810164932



Most Accessed Articles

Volumetric MRI Demonstrates Atrophy of the Olfactory Cortex in AD

, 2020; 17(10): 904-915.

Majed Al-Otaibi, Melissa Lessard-Beaudoin, Christian-Alexandre Castellano, Denis Gris, Stephen C. Cunnane and Rona K. Graham*


DOI: 10.2174/1567205017666201215120909






Mechanistic Modeling of Soluble Aβ Dynamics and Target Engagement in the Brain by Anti-Aβ mAbs in Alzheimer’s Disease

, 2020; 17(4): 393-406.

Gregory Z. Ferl*, Reina N. Fuji, Jasvinder K. Atwal, Tony Sun, Saroja Ramanujan and Angelica L. Quartino


DOI: 10.2174/1567205017666200302122307




Elucidating the Risk Factors for Progression from Amyloid-Negative Amnestic Mild Cognitive Impairment to Dementia

, 2020; 17(10): 893-903.

Hyung-Ji Kim, Jae-Hong Lee*, E-nae Cheong, Sung-Eun Chung, Sungyang Jo, Woo-Hyun Shim and Yun J. Hong


DOI: 10.2174/1567205017666201130094259










Editor-in-Chief

graphic
Prof. Debomoy K. Lahiri
(16607 citations)
Neuroscience Research Center
Indianapolis, IN 46202
(USA)
Biography
View Full Editorial Board

Nobel Laureates on Editorial Board

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Prof. Jean-Marie Lehn
(France)

graphic
Prof. Ferid Murad
(USA)

COPE Compliant

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Journal History

Current Alzheimer Research was introduced in 2004 with the assistance of Dr. Debomoy K. Lahiri, who is the current Editor-in-Chief serving since 2004.
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Frontiers in Clinical Drug Research – Alzheimer Disorders



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