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Current Alzheimer Research

Volume 16, 14 Issues, 2019
ISSN: 1875-5828 (Online)
ISSN: 1567-2050 (Print)
This journal supports open access

Ranking and Category

  • 65th of 197 in

    Clinical Neurology

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Aims & Scope

Current Alzheimer Research publishes peer-reviewed frontier review, research, drug clinical trial studies and letter articles on all areas of Alzheimer’s disease. This multidisciplinary journal will help in understanding the neurobiology, genetics, pathogenesis, and treatment strategies of Alzheimer’s disease. The journal publishes objective reviews written by experts and leaders actively engaged in research using cellular, molecular, and animal models. The journal also covers original articles on recent research in fast emerging areas of molecular diagnostics, brain imaging, drug development and discovery, and clinical aspects of Alzheimer’s disease. Manuscripts are encouraged that relate to the synergistic mechanism of Alzheimer's disease with other dementia and neurodegenerative disorders. Book reviews, meeting reports and letters-to-the-editor are also published. The journal is essential reading for researchers, educators and physicians with interest in age-related dementia and Alzheimer’s disease. Current Alzheimer Research provides a comprehensive 'bird's-eye view' of the current state of Alzheimer's research for neuroscientists, clinicians, health science planners, granting, caregivers and families of this devastating disease.

Current Alzheimer Research

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Volume 16

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Number 3



Research Article

Synthesis of New Galanthamine-Peptide Derivatives Designed for Prevention and Treatment of Alzheimer’s Disease

, 16(3): 183 - 192

Lyubomir T. Vezenkov*, Daniela S. Tsekova*, Ivanka Kostadinova, Rositsa Mihaylova, Nikolay G. Vassilev and Nikolai D. Danchev


DOI: 10.2174/1567205016666190228123923


Research Article

Identify Compounds' Target Against Alzheimer's Disease Based on In-Silico Approach

, 16(3): 193 - 208

Yan Hu, Guangya Zhou, Chi Zhang, Mengying Zhang, Qin Chen*, Linfeng Zheng* and Bing Niu*


DOI: 10.2174/1567205016666190103154855


Research Article

Inhibition of the PERK-Dependent Unfolded Protein Response Signaling Pathway Involved in the Pathogenesis of Alzheimer’s Disease

, 16(3): 209 - 218

Wioletta Rozpędek, Dariusz Pytel, Tomasz Popławski, Anna Walczak, Kinga Gradzik, Adam Wawrzynkiewicz, Radosław Wojtczak, Bartosz Mucha, John Alan Diehl and Ireneusz Majsterek*


DOI: 10.2174/1567205016666190228121157


Research Article



Research Article



Research Article



Research Article



Review Article



Articles Ahead of Print

Characterization of Serum Exosomes from a Transgenic Mouse Model of Alzheimer’s Disease


Hector Rosas-Hernandez, Elvis Cuevas, James B. Raymick, Bonnie L. Robinson, Syed F. Ali, Joseph Hanig and Sumit Sarkar*


View Abstract View on PubMed








The Role of MAPK's Signaling in Mediating ApoE4-Driven Pathology In Vivo


Shiran Salomon-Zimri , Amit Koren, Ariel Angel, Tali Ben-Zur, Daniel Offen and Daniel M. Michaelson*


View Abstract View on PubMed



N-alkylated Tacrine Derivatives as Potential Agents in Alzheimer’s Disease Therapy


Eugenie Nepovimov, Jan Korabecny, Vendula Hepnarova, Daniel Jun, Rafael Dolezal, Lubica Muckova , Petr Jost, Ondrej Soukup, Jana Janockova , Ngoc Lam Pham, Thuy Duong Nguyen, Martin Valis and Kamil Kuca*


View Abstract View on PubMed


Abstracts Ahead of Print

Is Brain-Derived Neurotrophic Factor a common link between neurodegenerative disorders and cancer?


Radhika Khosla, Avijit Banik, Sushant Kaushal, Priya Battu, Deepti Gupta and Akshay Anand*


View Abstract




Physical Activity as a Moderator of Alzheimer Pathology: a Systematic Review of Observational Studies


Kristian Steen Frederiksen*, Le Gjerum, Gunhild Waldemar and Steen Gregers Hasselbalch


View Abstract



Abnormal Saccadic Intrusions with Alzheimer's Disease in Darkness


Kiyotaka Nakamagoe*, Shiori Yamada, Rio Kawakami, Tadachika Koganezawa and Akira Tamaoka


View Abstract


Lead (Pb) in Alzheimer’s Dementia: A Systematic Review of Human Case-control Studies


Eric E. Brown, Parita Shah, Bruce G. Pollock, Philip Gerretsen and Ariel Graff-Guerrero*


View Abstract


Donepezil Derivatives Targeting Amyloid-β cascade in Alzheimer's Disease


Eva Mezeiova, Katarina Chalupova, Eugenie Nepovimova, Lukas Gorecki, Lukas Prchal, David Malinak, Kamil Kuca, Ondrej Soukup and Jan Korabecny*


View Abstract


Combination of Memantine and 6-Chlorotacrine as Novel Multi-Target Compound against Alzheimer’s Disease


Martina Kaniakova, Eugenie Nepovimova, Lenka Kleteckova, Kristyna Skrenkova, Kristina Holubova, Zofia Chrienova, Vendula Hepnarova, Tomas Kucera, Tereza Kobrlova, Karel Vales, Jan Korabecny, Ondrej Soukup and Martin Horak*


View Abstract


Editor's Choice


Synthesis of New Galanthamine-Peptide Derivatives Designed for Prevention and Treatment of Alzheimer’s Disease

, 2019; 16(3): 183 - 192

Lyubomir T. Vezenkov*, Daniela S. Tsekova*, Ivanka Kostadinova, Rositsa Mihaylova, Nikolay G. Vassilev and Nikolai D. Danchev


DOI: 10.2174/1567205016666190228123923




The Temporal Relationship between Pain Intensity and Pain Interference and Incident Dementia

, 2019; 16(2): 109 - 115

Ali Ezzati*, Cuiling Wang, Mindy J. Katz, Carol A. Derby, Andrea R. Zammit, Molly E. Zimmerman, Jelena M. Pavlovic, Martin J. Sliwinski and Richard B. Lipton


DOI: 10.2174/1567205016666181212162424



Impact of a Clinical Decision Support Tool on Dementia Diagnostics in Memory Clinics: The PredictND Validation Study

, 2019; 16(2): 91 - 101

Marie Bruun*, Kristian S. Frederiksen, Hanneke F.M. Rhodius-Meester, Marta Baroni, Le Gjerum, Juha Koikkalainen, Timo Urhemaa, Antti Tolonen, Mark van Gils, Tong Tong, Ricardo Guerrero, Daniel Rueckert, Nadia Dyremose, Birgitte Bo Andersen, Anja H. Simonsen, Afina Lemstra, Merja Hallikainen, Sudhir Kurl, Sanna-Kaisa Herukka, Anne M. Remes, Gunhild Waldemar, Hilkka Soininen, Patrizia Mecocci, Wiesje M. van der Flier, Jyrki Lötjönen and Steen G. Hasselbalch


DOI: 10.2174/1567205016666190103152425



Visual Event-Related Potentials in Mild Cognitive Impairment and Alzheimer’s Disease: A Literature Review

, 2019; 16(1): 67 - 89

Cassandra Morrison*, Sheida Rabipour, Vanessa Taler, Christine Sheppard and Frank Knoefel


DOI: 10.2174/1567205015666181022101036



Intranasal Insulin Prevents Anesthesia-induced Cognitive Impairments in Aged Mice

, 2019; 16(1): 8 - 18

Xing Li, Xiaoqin Run*, Zhen Wei, Kuan Zeng, Zhihou Liang, Fang Huang, Dan Ke, Qun Wang, Jian-Zhi Wang, Rong Liu, Bin Zhang* and Xiaochuan Wang*


DOI: 10.2174/1567205015666181031145045




Stroke as a Cause of Death in Death Certificates of Patients with Dementia: A Cohort Study from the Swedish Dementia Registry

, 2018; 15(14): 1322 - 1330

Ana Subic*, Eva Zupanic, Mia von Euler, Bo Norrving, Pavla Cermakova, Dorota Religa, Bengt Winblad, Milica G. Kramberger, Maria Eriksdotter and Sara Garcia-Ptacek


DOI: 10.2174/1567205015666181002134155




Open Access Articles

Impact of a Clinical Decision Support Tool on Dementia Diagnostics in Memory Clinics: The PredictND Validation Study

, 2019; 16(2): 91 - 101

Marie Bruun*, Kristian S. Frederiksen, Hanneke F.M. Rhodius-Meester, Marta Baroni, Le Gjerum, Juha Koikkalainen, Timo Urhemaa, Antti Tolonen, Mark van Gils, Tong Tong, Ricardo Guerrero, Daniel Rueckert, Nadia Dyremose, Birgitte Bo Andersen, Anja H. Simonsen, Afina Lemstra, Merja Hallikainen, Sudhir Kurl, Sanna-Kaisa Herukka, Anne M. Remes, Gunhild Waldemar, Hilkka Soininen, Patrizia Mecocci, Wiesje M. van der Flier, Jyrki Lötjönen and Steen G. Hasselbalch





Probiotic Supplementation in Patients with Alzheimer’s Dementia - An Explorative Intervention Study

, 2018; 15(12): 1106 - 1113

Friedrich Leblhuber, Kostja Steiner, Burkhard Schuetz, Dietmar Fuchs* and Johanna M. Gostner




Technological Solutions for Older People with Alzheimer’s Disease: Review

, 2018; 15(10): 975 - 983

Petra Maresova*, Signe Tomsone, Petre Lameski, Joana Madureira, Ana Mendes, Eftim Zdravevski, Ivan Chorbev, Vladimir Trajkovik, Moriah Ellen and Kasper Rodile





Interplay between the APOE Genotype and Possible Plasma Biomarkers in Alzheimer’s Disease

, 2018; 15(10): 938 - 950

Martina Zverova, Eva Kitzlerova, Zdenek Fisar*, Roman Jirak, Jana Hroudova, Hana Benakova, Petra Lelkova, Pavel Martasek and Jiri Raboch





Up-regulation of DMN Connectivity in Mild Cognitive Impairment Via Network-based Cognitive Training

, 2018; 15(6): 578 - 589

Matteo De Marco, Francesca Meneghello, Cristina Pilosio, Jessica Rigon and Annalena Venneri*





Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment

, 2018; 15(5): 482 - 492

Kiyomi Nishimaki, Takashi Asada*, Ikuroh Ohsawa, Etsuko Nakajima, Chiaki Ikejima, Takashi Yokota, Naomi Kamimura and Shigeo Ohta*




Evaluation of Metabolic and Synaptic Dysfunction Hypotheses of Alzheimer's Disease (AD): A Meta-Analysis of CSF Markers

, 2018; 15(2): 164 - 181

Roni Manyevitch, Matthew Protas, Sean Scarpiello, Marisa Deliso, Brittany Bass, Anthony Nanajian, Matthew Chang, Stefani M. Thompson, Neil Khoury, Rachel Gonnella, Margit Trotz, D. Blaine Moore, Emily Harms, George Perry, Lucy Clunes, Angelica Ortiz, Jan O. Friedrich and Ian V.J. Murray*




A Speech Recognition-based Solution for the Automatic Detection of Mild Cognitive Impairment from Spontaneous Speech

, 2018; 15(2): 130 - 138

Laszlo Toth*, Ildiko Hoffmann, Gabor Gosztolya, Veronika Vincze, Greta Szatloczki, Zoltan Banreti, Magdolna Pakaski and Janos Kalman




Biomarkers for Alzheimer's Disease Diagnosis

, 2017; 14(11): 1149 - 1154

Vasileios Mantzavinos and Athanasios Alexiou*




iTRAQ-based Proteomic Analysis of APPSw,Ind Mice Provides Insights into the Early Changes in Alzheimer’s Disease

, 2017; 14(10): 1109 - 1122

Nan Li, Pinghong Hu, Tiantian Xu, Huan Chen, Xiaoying Chen, Jianwen Hu, Xifei Yang, Lei Shi, Jian-hong Luo and Junyu Xu*




Association between Periodontal Health Status and Cognitive Abilitie s. The Role of Cytokine Profile and Systemic Inflammation

, 2017; 14(9): 978 - 990

Marta Sochocka*, Maciej Sobczyński , Aleksandra Sender-Janeczek , Katarzyna Zwolińska , Olga Błachowicz , Tomasz Tomczyk, Marek Ziętek and Jerzy Leszek





Most Cited Articles


Glutamate and Mitochondria: Two Prominent Players in the Oxidative Stress-Induced Neurodegeneration

, 2016; 13(2): 185-197.

Tommaso Cassano, Lorenzo Pace, Gaurav Bedse, Angelo Michele Lavecchia, Federico De Marco, Silvana Gaetani and Gaetano Serviddio


DOI: 10.2174/1567205013666151218132725


Noradrenergic System in Down Syndrome and Alzheimer’s Disease A Target for Therapy

, 2016; 13(1): 68-83.

Cristy Phillips, Atoossa Fahimi, Devsmita Das, Fatemeh S. Mojabi, Ravikumar Ponnusamy and Ahmad Salehi


DOI: 10.2174/1567205012666150921095924


Complex and Differential Glial Responses in Alzheimer´s Disease and Ageing

, 2016; 13(4): 343-358.

José J. Rodríguez, Arthur M. Butt, Emanuela Gardenal, Vladimir Parpura and Alexei Verkhratsky


DOI: 10.2174/1567205013666160229112911


Glial Cells – The Key Elements of Alzheimer´s Disease

, 2016; 13(8): 894-911.

David Dzamba, Lenka Harantova, Olena Butenko and Miroslava Anderova


DOI: 10.2174/1567205013666160129095924





Peripheral Immune Signatures in Alzheimer Disease

, 2016; 13(7): 739-749.

David Goldeck, Jacek M. Witkowski, Tamas Fülop and Graham Pawelec


DOI: 10.2174/1567205013666160222112444




Most Accessed Articles

Impact of a Clinical Decision Support Tool on Dementia Diagnostics in Memory Clinics: The PredictND Validation Study

, 2019; 16(2): 91-101.

Marie Bruun*, Kristian S. Frederiksen, Hanneke F.M. Rhodius-Meester, Marta Baroni, Le Gjerum, Juha Koikkalainen, Timo Urhemaa, Antti Tolonen, Mark van Gils, Tong Tong, Ricardo Guerrero, Daniel Rueckert, Nadia Dyremose, Birgitte Bo Andersen, Anja H. Simonsen, Afina Lemstra, Merja Hallikainen, Sudhir Kurl, Sanna-Kaisa Herukka, Anne M. Remes, Gunhild Waldemar, Hilkka Soininen, Patrizia Mecocci, Wiesje M. van der Flier, Jyrki Lötjönen and Steen G. Hasselbalch


DOI: 10.2174/1567205016666190103152425


Probiotic Supplementation in Patients with Alzheimer’s Dementia - An Explorative Intervention Study

, 2018; 15(12): 1106-1113.

Friedrich Leblhuber, Kostja Steiner, Burkhard Schuetz, Dietmar Fuchs* and Johanna M. Gostner


DOI: 10.2174/1389200219666180813144834


The Implications of Autophagy in Alzheimer’s Disease

, 2018; 15(14): 1283-1296.

Tadanori Hamano*, Kouji Hayashi, Norimichi Shirafuji and Yasunari Nakamoto


DOI: 10.2174/1567205015666181004143432


Stroke as a Cause of Death in Death Certificates of Patients with Dementia: A Cohort Study from the Swedish Dementia Registry

, 2018; 15(14): 1322-1330.

Ana Subic*, Eva Zupanic, Mia von Euler, Bo Norrving, Pavla Cermakova, Dorota Religa, Bengt Winblad, Milica G. Kramberger, Maria Eriksdotter and Sara Garcia-Ptacek


DOI: 10.2174/1567205015666181002134155


Current State of Saliva Biomarkers for Aging and Alzheimer’s Disease

, 2019; 16(1): 56-66.

Maxime François*, Caroline F. Bull, Michael F. Fenech and Wayne R. Leifert


DOI: 10.2174/1567205015666181022094924


Alzheimer's Disease-Like Pathologies and Cognitive Impairments Induced by Formaldehyde in Non-Human Primates

, 2018; 15(14): 1304-1321.

Rongwei Zhai, Joshua Rizak, Na Zheng, Xiaping He, Zhenhui Li, Yong Yin, Tao Su, Yingge He, Rongqiao He, Yuanye Ma, Meifeng Yang*, Zhengbo Wang* and Xintian Hu*


DOI: 10.2174/1567205015666180904150118


Alterations in the Expression of Amyloid Precursor Protein Cleaving Enzymes mRNA in Alzheimer Peripheral Blood

, 2019; 16(1): 29-38.

Prapimpun Wongchitrat*, Nattaporn Pakpian, Kuntida Kitidee, Kamonrat Phopin, Pornpatr A. Dharmasaroja and Piyarat Govitrapong


DOI: 10.2174/1567205015666181109103742



Crosstalk between Gut Microbiota and Central Nervous System: A Focus on Alzheimer's Disease

, 2018; 15(13): 1179-1190.

Vilma M. Junges, Vera E. Closs, Guilherme M. Nogueira and Maria G.V. Gottlieb*


DOI: 10.2174/1567205015666180904155908




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