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Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Volume 25, 14 Issues, 2022
ISSN: 1875-5402 (Online)
ISSN: 1386-2073 (Print)
This journal supports open access

Articles Ahead of Print





Can We Use mTOR Inhibitors for COVID-19 Therapy?


Ina Y. Aneva *, Solomon Habtemariam, Maciej Banach, Parames C. Sil , Kasturi Sarkar, Adeleh Sahebnasagh , Mohammad Amjad Kamal, Maryam Khayatkashani and Hamid Reza Khayat Kashani*


DOI: 10.2174/1386207325666211130140923
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miR-4295 Promotes the Malignant Progression of Gastric Cancer via Targeting PTEN


Xiaoyan Yang, Jing Yang, Yunlian Tang, Zhizhong Xie, Yang Zhang, Xiaoyong Lei* and Runliang Gan*


DOI: 10.2174/1386207325666211110095307
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Amalgamation and Scrutinizing of Leucine Derivatives Schiff Bases Complexes as Antimicrobial Agent


Muhammad Pervaiz*, Ikram Ahmad, Zohaib Saeed, Muhammad Sagir, Umer Younas, Muhammad Bilal Tahir*, Awais Ahmad, Ayoub Rashid, Quratulain Syed and Ahmad Adnan


DOI: 10.2174/1386207325666210927092623
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A Review on Phyto-pharmacology of Oxalis corniculata


Iqra Sarfraz, Azhar Rasul*, Ghulam Hussain, Muhammad Ajmal Shah*, Bushra Nageen, Farhat Jabeen, Zeliha Selamoğlu, İlknur UÇAK, Muhammad Asrar and Sevki Adem


DOI: 10.2174/1386207324666210813121431
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COVID-19 Candidate Genes and Pathways Potentially Share the Association with Lung Cancer


Afnan M. Alnajeebi*, Hend F.H. Alharbi, Walla Alelwani, Nouf A. Babteen, Wafa Alansari, Ghalia Shamlan and Areej A. Eskandrani


DOI: 10.2174/1386207324666210712092649
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Fagonia arabica L.: A Review of its Phytochemistry, Pharmacology and Traditional Uses


Neelam Iftikhar, Shahzad Ali Shahid Chatha, Tanveer Ahmad, Qasim Ali, Abdullah Ijaz Hussain* and Hassaan Anwer Rathore*


DOI: 10.2174/1386207325666210923120957
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Polyphenolic Natural Products Active In Silico Against SARS-CoV-2 Spike Receptor Binding Domains and Non-structural Proteins - A Review


Mark Tristan Quimque, Kin Israel Notarte, Xela Amor Adviento, Mikhail Harvey Cabunoc, Von Novi de Leon, Felippe Steven Louis delos Reyes, Eiron John Lugtu, Joe Anthony Manzano, Sofia Nicole Monton, John Emmanuel Muñoz, Katherine Denise Ong, Delfin Yñigo Pilapil IV, Vito Roque III, Sophia Morgan Tan, Justin Allen Lim and Allan Patrick Macabeo*


DOI: 10.2174/1386207325666210917113207
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Synthesis and Antinociceptive Activity of Newly Modified Amine Analogs of Phencyclidine in Mice


Maryam Shokrollahi, Marjaneh Samadizadeh, Mohsen Khalili, Seyed Ali Sobhanian and Abbas Ahmadi*


DOI: 10.2174/1386207325666211005155128
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Network Pharmacology Analysis of the Effects of Achyranthis Bidentatae Radix Plus Semen Vaccariae on Migraine-induced Erectile Dysfunction


Jisheng Wang, Junlong Feng, Sheng Deng, Binghao Bao, Fanchao Meng, Hengheng Dai, Hongsheng Xu, Shizhen Wang, Bin Wang * and Haisong Li*


DOI: 10.2174/1386207324666210628105233
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Amelioration of Experimental Hepatotoxicity in Rats by Portulaca oleracea Linn. from Kashmir Himalaya


Mohd Akbar Dar*, Prince Ahad Mir, Mubashir Hussain Masoodi*, Ali S. Alqahtani, Nasir A. Siddiqui and Bahar Ahmad


DOI: 10.2174/1386207324666210713104836
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In Vitro Antifungal Screening of Argentine Native or Naturalized Plants against the Phytopathogen Monilinia fructicola


María Inés Stegmayer, Laura Noemí Fernández, Norma Hortensia Álvarez, Gisela Marisol Seimandi, Andrea Guadalupe Reutemann and Marcos Gabriel Derita*


DOI: 10.2174/1386207324666210121113648
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FABP1 Gene Variant is Associated with Risk of Metabolic Syndrome


Reza Zare-Feyzabadi, Majid Mozaffari*, Majid Ghayour-Mobarhan* and Mohsen Valizadeh


DOI: 10.2174/1386207324666210603114434
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Trimethoxy Crown Chalcones as Multifunctional Class of Monoamine Oxidase Enzyme Inhibitors


Naseer Maliyakkal*, Ipek Baysal, Anandkumar Tengli, Gulberk Ucar*, Mohammad Ali Abdullah Almoyad, Della Grace Thomas Parambi, Nicola Gambacorta, Orazio Nicolotti, Asmy Appadath Beeran and Bijo Mathew*


DOI: 10.2174/1386207324666210603125452
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Relationship Between Clinical, Demographic and Socioeconomic Factors with Suicide Ideation; A Cross-sectional Study


Hamideh Ghazizadeh*, Mahdiyeh Yaghooti Khorasani*, Niloofar Shabani*, Toktam Sahranavard*, Reza Zare-Feyzabadi, Maryam Mohammadi-Bajgiran, Ameneh Timar, Mohammad Reza Oladi, Sara Moazedi, Negin Mosalman-Zadeh, Hamed Khedmatgozar, Mohadeseh Rohban, Elahe Hasanzadeh, Ali Javandoost, Shahin Nazarpour, Afsaneh Bahrami, Gordon A. Ferns, Ali Akbar Haghdoost, Habibollah Esmaily* and Majid Ghayour-Mobarhan*


DOI: 10.2174/1386207324666210302094438
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3 CpG Methylation Biomarkers for the Diagnosis of Polycystic Ovary Syndrome (PCOS) in Blood Samples


Linling Xie, Xiaotao Jiang, Yi Chen, Cihui Huang, Yanfen Chen, Guantong Liu, Wenxi Sun, Lei Zeng* and Ruling Lu*


DOI: 10.2174/1386207321666210602170054
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Development of 2D, 3D-QSAR and Pharmacophore Modeling of Chalcones for the Inhibition of Monoamine Oxidase B


Bijo Mathew*, Chonny Herrera-Acevedo, Sanal Dev, T. M. Rangarajan, Mohamed Saheer Kuruniyan, Punnoth Poonkuzhi Naseef, Luciana Scotti and Marcus Tullius Scotti*


DOI: 10.2174/1386207324666210816125738
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Screening of Candidate Pathogenic Genes for Spontaneous Abortion Using Whole Exome Sequencing


Qingwen Zhu, Jia Liu, Li Chen, Yiwen Zhou, Tao Zhou, Wenjun Bian, Guohui Ding, Guang Li* and Jiayi Ding


DOI: 10.2174/1386207324666210628115715
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Effects of Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Fructose and Potassium Oxonate


Yu-Zhi Wang, Cong Zhou*, Li-Jie Zhu, Xing-Li-Shang He, Lin-Zi Li, Xiang Zheng, Wan-Feng Xu, Ying-Jie Dong, Bo Li, Qiao-Xian Yu*, Gui-Yuan Lv* and Su-Hong Chen*


DOI: 10.2174/1386207324666210528114345
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Free Convective Flow of Hamilton-Crosser Model Gold-water Nanofluid Through a Channel with Permeable Moving Walls


Pradyuna Kuar Pattnaik, Munawwar Ali Abbas, Satyaranjan Mishra, Sami Ullah Khan and Muhammad Mubashir Bhatti*


DOI: 10.2174/1386207324666210813112323
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Current Perspective of COVID-19 on Neurology: A Mechanistic Insight


Rajesh Kumar, Seetha Harilal, Sabitha M., Leena K. Pappachan, Roshni P.R. and Bijo Mathew*


DOI: 10.2174/1386207324666210805121828
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Systematic Optimisation of Microtiter Plate Lectin Assay to Improve Sialic Acid Linkage Detection


Nur Hanina Izzati Khairol Mokhtar, Ainulkhir Hussin, Aidil Abdul Hamid, Shahrul Hisham Zainal Ariffin and Muhammad Ashraf Shahidan*


DOI: 10.2174/1386207324666210802122538
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Xanthine Oxidase Inhibitory Activity of Euphorbia peplus L. Phenolics


Emadeldin M. Kamel, Noha A. Ahmed, Ashraf A. El-Bassuony, Omnia E. Hussein, Barakat Alrashdi, Sayed A. Ahmed, Al Mokhtar Lamsabhi, Hany H. Arab and Ayman M. Mahmoud*


DOI: 10.2174/1386207324666210609104456
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Combinatorial Synthesis of Novel 1-sulfonyloxy/acyloxyeugenol Derivatives as Fungicidal Agents


Genqiang Chen, Lina Zhu, Jiaxuan He, Song Zhang, Yuanhao Li, Xiaolong Guo, Di Sun, Yuee Tian, Shengming Liu, Xiaobo Huang and Zhiping Che*


DOI: 10.2174/1386207324666210813114829
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Comparative Proteomic Analysis Reveals Novel Biomarkers for Gastric Cancer in South Indian Tamil Population


Ananthi Sivagnanam, Balasankar Thangasamy, Vignesh Nagarajan, Subeksha Govindarajan Ravi, Jeevitha Chithra Madhesh, Manikandan Athilinga Perumal, Premkumar Karunakaran and Megala Jayaraman*


DOI: 10.2174/1386207324666210603120320
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A Prognostic Nomogram for Predicting Overall Survival in Pediatric Wilms Tumor Based on an Autophagy-related Gene Signature


Longkai He, Xiaotong Wang, Ya Jin, Weipeng Xu, Jun Lyu, Yi Guan, Jingchao Wu, Shasha Han* and Guosheng Liu*


DOI: 10.2174/1386207324666210826143727
View Abstract



Current Application of Chemometrics Analysis in Authentication of Natural Products: A Review


Abdelkrim Rebiai, Hadia Hemmami, Soumeia Zeghoud, Bachir Ben Seghir*, Imane Kouadri, Laouini Salah Eddine, Noureddine Elboughdiri, Saad Ghareba, Djamel Ghernaout and Nadir Abbas


DOI: 10.2174/1386207324666210309102239
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Combinatorial Synthesis of Novel 3/5(3,5)-(Di)nitro/chloropaeonol Carbonyl Hydrazone Derivatives as Nematicidal Agents


Genqiang Chen, Lina Zhu, Yanfei Xia, Jinming Yang, Song Zhang, Yuanhao Li, Xiaolong Guo, Di Sun, Jiaxuan He, Yuee Tian, Shengming Liu, Jia Jiang and Zhiping Che*


DOI: 10.2174/1386207324666210324145627
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FEN1 Status and Its Correlation with Clinicopathologic Characteristic in Colorectal Cancer


Yundi Guo*, Zixuan Du *, Yuanshuai Zhou, Haijun Sun, Rui Liang, Min-Xuan Sun, Zaixiang Tang and Song-Bai Liu


DOI: 10.2174/1386207324666210401113351
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Rapid Identification of Commercial Frankincense Products by MALDITOF Mass Spectrometry


Shang-Chih Lai, Ren-In You, Tz-Ting Chen, Yu Chang, Chao-Zong Liu, Hao-Ping Chen* and Chunhung Wu*


DOI: 10.2174/1386207324666210301092111
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Pouteria sapota (Red Mamey Fruit): Chemistry and Biological Activity of Carotenoids


Johant Lakey-Beitia, Velmarini Vasquez, Randy Mojica-Flores, Arelys L. Fuentes C., Enrique Murillo, Muralidhar L. Hedge and K.S. Rao*


DOI: 10.2174/1386207324666210301093711
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Synergistic Extraction of Europium (III) using Di-n-Butylsulfoxide and Picrolonic Acid


Srosh Fazil, Farid Menaa*, Khurram Liaqat, Muhammad Haleem Khan, Wajid Rehman*, Mohammad Mansoob Khan, Siraj ul Haq, Muhammad Sajid, Muhammad Farooq, Bouzid Menaa and Muhammad Hafeez


DOI: 10.2174/1386207324666210210105511
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Ovarian Hyperresponse Following the Sole Administration of GnRH Agonist


Cheng Chen*, Lan Geng, Zhenhui Hou, Dan Liu, Fanhua Meng, Wenmin Ma* and Xi Xia*


DOI: 10.2174/1386207324666210302095049
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Two Promising Anti-Cancer Compounds, 2-Hydroxycinnaldehyde and 2- Benzoyloxycinnamaldehyde: Where do we stand?


Haroon Iqbal, Farid Menaa*, Naveed Ullah Khan, Anam Razzaq, Zaheer Ullah Khan, Kifayat Ullah, Robia Kamal, Muhammad Sohail, Gobika Thiripuranathar, Bushra Uzair, Nosheen Fatima Rana, Barkat Ali Khan and Bouzid Menaa


DOI: 10.2174/1386207324666210216094428
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Virus as a Nanocarrier for Drug Delivery Redefining Medical Therapeutics - A Status Report


Sanjay Kumar Ojha*, Ritesh Pattnaik, Puneet Kumar Singh, Shubha Dixit, Snehasish Mishra, Sreyasi Pal and Subrat Kumar*


DOI: 10.2174/1386207323666201218115850
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Therapeutic Properties of PDMS Nanoparticles: A Promising New Drug Delivery Vehicle Against Inflammatory Conditions


Aiswarya Anilkumar Ajitha, Sri SivaKumar, Gayathri Viswanathan, Sabulal Baby and Prabath Gopalakrishnan Biju*


DOI: 10.2174/1386207324666210210112843
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Editor-in-Chief

Gerald H. Lushington
LiS Consulting
Lawrence, KS
(USA)
Biography
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Journal History

Combinatorial Chemistry & High Throughput Screening Journal was launched in 1998. Dr. Gerald H. Lushington serves as the Editor-in-Chief of the journal.

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