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Clinical Cancer Drugs

Volume 7, 2 Issues, 2020
ISSN: 2212-6988 (Online)
ISSN: 2212-697X (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Clinical Cancer Drugs publishes original research, full-length reviews/ mini reviews, and thematic issues in all core areas of translational and clinical cancer drug research.

The journal publishes pre-clinical and clinical studies on the development of new anti-cancer agents. Clinical studies of new reported anti-cancer drugs include Phase 1–IV clinical trial studies, their designs, research methodologies, and analyses. The journal is essential reading for clinical oncologists, toxicologists, medicinal chemists, and pharmacologists.

Clinical Cancer Drugs

,

Volume 7

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Number 1



Preface   Open Access



Biography   Open Access



Review Article   Open Access



Research Article   Open Access

Metformin Treatment Sensitizes Human Laryngeal Cancer Cell Line Hep- 2 to 5-Fluorouracil

, 7(1): 16 - 24

Neslisah Barlak, Fatma Sanli, Ozel Capik, Elanur Tuysuz, Elanur Aydın Karatas, Hasan Turkez and Omer Faruk Karatas*


DOI: 10.2174/2212697X06666190906165309


Research Article   Open Access



Research Article   Open Access



Clinical Trial   Open Access



Clinical Cancer Drugs, Volume 7 (2020) - Number 2


This issue is in progress but contains articles that are final and fully citable.

Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Editor's Choice




Arachidonic Acid Induces the Migration of MDA-MB-231 Cells by Activating Raft-associated Leukotriene B4 Receptors

, 2018; 5(1): 28 - 41

Atasi De Chatterjee, Debarshi Roy, Priscilla Guevara, Rituraj Pal, Mahesh Narayan, Sukla Roychowdhury and Siddhartha Das*


DOI: 10.2174/2212697X05666180418145601



Prevalence of Neuropathy Associated With Bortezomib: A Retrospective Study

, 2017; 4(1): 69 - 72

Pulivarthi Swaroopa, Mathew Josy, Ehresmann Kirsten and Gurram Murali Krishna*


DOI: 10.2174/2212697X03666161128102453





Inhibition of Autophagy by Targeting ATG4B: Promises and Challenges of An Emerging Anti-cancer Strategy

, 2015; 2(1): 61 - 70

Kelly Lien, Michelle Rocha, Elisa Tran, Van C. Hoang, Annabelle Chow and Urban Emmenegger


DOI: 10.2174/2212697X02666150331202809



Impaired Autophagy Mediates Resistance to Low-Dose Metronomic Cyclophosphamide Chemotherapy

, 2014; 1(2): 116 - 126

Annabelle Chow, Giulio Francia, Andrew Kouri, Christina Lee, John M. Ebos, Robert S. Kerbel and Urban Emmenegger


DOI: 10.2174/2212697X01666131218235200



The Epithelial-Stromal Interaction as a Potential Target for Breast Cancer Treatment

, 2014; 1(1): 65 - 71

Bianca Maria Veneziani, Micaela Montanari, Maria Letizia Cataldo, Luigi Coppola, Agostina Nardone, Sara Corvigno, Carmine De Angelis, Grazia Arpino, Mario Giuliano, Chiara Carlomagno, Roberto Bianco and Sabino De Placido


DOI: 10.2174/2212697X113016660008



Open Access Articles

A Phase I Study of OMN54 (Aneustat™) in Patients with Advanced Malignancies

, 2020; 7(2): 125 - 132

Karen A. Gelmon*, Christian Kollmannsberger, Stephen Chia, Anna V. Tinker, Teresa Mitchell, Stephen Lam, Teresa Joshi, David Kwok, John Ostrem, Simon Sutcliffe and Daniel J. Renouf




Clinical Impact of Gastric Acid Suppressants Use on the Efficacy of Gefitinib in Patients with Advanced Adenocarcinoma of the Lung Harboring Common EGFR Mutations

, 2020; 7(1): 57 - 61

Wang Chun Kwok, James Chung Man Ho, David Chi Leung Lam, Macy Mei Sze Lui, Mary Sau Man Ip and Terence Chi Chun Tam*




Melatonin Induces Apoptosis and Inhibits the Proliferation of Cancer Cells via Reactive Oxygen Species-mediated MAPK and mTOR Pathways

, 2020; 7(1): 44 - 56

Reena Kasi, Pei Ling Yeo, Ng. Khuen Yen, Rhun Yian Koh, Gnanajothy Ponnudurai, Yee Lian Tiong and Soi Moi Chye*




Complexity in Clinical Trials: Blind Spots, Misleading Criteria, Winners and Losers

, 2020; 7(1): 3 - 15

Gang Yuan, Lishi Wang, Jing Li, Helin Feng, Jiafu Ji, Weikuan Gu* and Baoen Shan*




The Potential Role of Claudins in Regulation of Metastasis and Development of Drug Resistance in Breast Cancer

, 2020; 7(1): 25 - 43

Hemantkumar Patadia, Ankita Priyadarshini, Jay Ranade and Ajit Gangawane*




Metformin Treatment Sensitizes Human Laryngeal Cancer Cell Line Hep- 2 to 5-Fluorouracil

, 2020; 7(1): 16 - 24

Neslisah Barlak, Fatma Sanli, Ozel Capik, Elanur Tuysuz, Elanur Aydın Karatas, Hasan Turkez and Omer Faruk Karatas*





Head and Neck Cancer with Lung Metastases: Treatment Challenges

, 2019; 6(1): 48 - 53

Selvamalar Vengathajalam* and Norhafiza Mat Lazim







Evaluation of Fibrolytic Effect of Bauhinia purpurea L.

, 2019; 6(1): 21 - 32

Jeevan R. Dash, Tapas K. Sar*, Rinku Buragohain, Indranil Samanta and Rahul Nanotkar








Most Cited Articles

Upfront DPD Deficiency Detection to Secure 5-FU Administration: Part 1 – Where Do We Stand?

, 2017; 4(2): 74-81.

Manon Launay, Joseph Ciccolini*, Anne Rodallec, Claire Fournel, Florence Duffaud, Sebastien Salas and Bruno Lacarelle


DOI: 10.2174/2212697X04666170531080625


The PI3K/AKT/mTOR-Signal Transduction Pathway as Drug Target in Triple-Negative Breast Cancer

, 2017; 4(1): 47-58.

Jens C. Hahne*, Jorg B. Engel, Arnd Honig, Susanne R. Meyer, Domenico Zito, Andrea Lampis and Nicola Valeri


DOI: 10.2174/2212697X04666170321112629


Intra-arterial Temozolomide, Osmotic Blood-brain Barrier Disruption and Radiotherapy in a Rat F98-Glioma Model

, 2017; 4(2): 135-144.

Annie I. Drapeau, Marie-Belle Poirier, Guru-Swamy Madugundu, J. Richard Wagner and David Fortin*


DOI: 10.2174/2212697X04666170727152212


Pharmacokinetic Markers of 5-Fluorouracil Toxicity in Clinical Trials and Real World

, 2017; 4(2): 82-92.

Antonello Di Paolo*, Marzia Del Re, Elena Arrigoni, Teresa Di Desidero, Eleonora Rofi, Romano Danesi and Guido Bocci


DOI: 10.2174/2212697X04666170817124625



Most Accessed Articles

Metformin Treatment Sensitizes Human Laryngeal Cancer Cell Line Hep- 2 to 5-Fluorouracil

, 2020; 7(1): 16-24.

Neslisah Barlak, Fatma Sanli, Ozel Capik, Elanur Tuysuz, Elanur Aydın Karatas, Hasan Turkez and Omer Faruk Karatas*


DOI: 10.2174/2212697X06666190906165309



Preclinical Models to Study Breast Cancer

, 2014; 1(2): 90-99.

Cynthia M. Rodriguez, Paloma Valenzuela, Natzidielly Lerma and Giulio Francia


DOI: 10.2174/2212697X113026660005


Castration Resistant Prostate Cancer: From Emerging Molecular Pathways to Targeted Therapeutic Approaches

, 2014; 1(1): 11-27.

Patrizia Limonta, Roberta M. Moretti, Monica Marzagalli and Marina Montagnani Marelli


DOI: 10.2174/2212697X0101131204151357



Melatonin Induces Apoptosis and Inhibits the Proliferation of Cancer Cells via Reactive Oxygen Species-mediated MAPK and mTOR Pathways

, 2020; 7(1): 44-56.

Reena Kasi, Pei Ling Yeo, Ng. Khuen Yen, Rhun Yian Koh, Gnanajothy Ponnudurai, Yee Lian Tiong and Soi Moi Chye*


DOI: 10.2174/2212697X06666191116151114


Complexity in Clinical Trials: Blind Spots, Misleading Criteria, Winners and Losers

, 2020; 7(1): 3-15.

Gang Yuan, Lishi Wang, Jing Li, Helin Feng, Jiafu Ji, Weikuan Gu* and Baoen Shan*


DOI: 10.2174/2212697X06666191021125423



Recent Clinical Advances in the Treatment of Cutaneous Melanoma

, 2015; 2(1): 16-28.

Martin Greco, Maximiliano Mestroni, Maximo de la Vega, Gonzalo Recondo, Matias E. Valsecchi, Gonzalo Recondo and Enrique Diaz Canton


DOI: 10.2174/2212697X02666150203212708


Molecular Components of Wnt/β-catenin Pathway As Therapeutic Targets For Upper Gastrointestinal Cancers

, 2015; 2(2): 72-79.

Nikki P. Lee, Zhi Xu, Sarwat Fatima, Timothy T. Yung, Raymond W. Y. Sun and Simon Law


DOI: 10.2174/2212697X02666151028192148



Editor-in-Chief

Giulio Francia
The University of Texas
El Paso, TX
(USA)
Biography
View Full Editorial Board

Journal History

Clinical Cancer Drugs was introduced in 2014 with the assistance of Dr. Giulio Francia, who is the current Editor-in-Chief serving since 2014.

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