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Current Gene Therapy

Volume 19, 6 Issues, 2019
ISSN: 1566-5232 (Print)
ISSN: 1875-5631 (Online)
This journal supports open access

Ranking and Category

  • 115th of 171 in

    Genetics & Heredity

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Aims & Scope

Current Gene Therapy is a bi-monthly peer-reviewed journal aimed at academic and industrial scientists with an interest in major topics concerning basic research and clinical applications of gene and cell therapy of diseases. Cell therapy manuscripts can also include application in diseases when cells have been genetically modified. Current Gene Therapy publishes full-length/mini reviews and original research on the latest developments in gene transfer and gene expression analysis, vector development, cellular genetic engineering, animal models and human clinical applications of gene and cell therapy for the treatment of diseases.

Current Gene Therapy publishes reviews and original research containing experimental data on gene and cell therapy. The journal also includes manuscripts on technological advances, ethical and regulatory considerations of gene and cell therapy. Reviews should provide the reader with a comprehensive assessment of any area of experimental biology applied to molecular medicine that is not only of significance within a particular field of gene therapy and cell therapy but also of interest to investigators in other fields. Authors are encouraged to provide their own assessment and vision for future advances. Reviews are also welcome on late breaking discoveries on which substantial literature has not yet been amassed. Such reviews provide a forum for sharply focused topics of recent experimental investigations in gene therapy primarily to make these results accessible to both clinical and basic researchers. Manuscripts containing experimental data should be original data, not previously published.

Current Gene Therapy

,

Volume 18

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Number 6



Biography   Open Access



Review Article   Open Access



Review Article



Review Article



Research Article   Open Access

Clinical-Grade Oncolytic Adenovirus Purification Using Polysorbate 20 as an Alternative for Cell Lysis

, 18(6): 366 - 374

Mafalda G. Moleirinho, Sara Rosa, Manuel J.T. Carrondo*, Ricardo J.S. Silva, Åsa Hagner-McWhirter, Gustaf Ahlén, Mats Lundgren, Paula M. Alves and Cristina Peixoto


DOI: 10.2174/1566523218666181109141257


Research Article

Design of Artificial Immunogens Containing Melanoma-associated T-cell Epitopes

, 18(6): 375 - 385

E.A. Borobova*, D.V. Antonets, E.V. Starostina, L.I. Karpenko, A.A. Ilyichev and S.I. Bazhan


DOI: 10.2174/1566523218666181113112829


Clinical Trial   Open Access

Clinical Observation of Patients with Leber’s Hereditary Optic Neuropathy Before Gene Therapy

, 18(6): 386 - 392

Jiajia Yuan, Yong Zhang, Hongli Liu, Zhen Tian, Xin Li, Yichen Zheng, Qin Gao, Lin Song, Xiao Xiao, Jian Sun, Zhitao Wang and Bin Li*


DOI: 10.2174/1566523218666181105125245


Acknowledgement   Open Access



Articles Ahead of Print

Perspectives in Gene therapy of Anderson-Fabry Disease


Antonino Tuttolomondo, Irene Simonetta* and Antonio Pinto







Functional Improvement of Chimeric Antigen Receptor Through Intrinsic Interleukin-15Rα Signaling


Sushmita Nair, Jing-Bo Wang, Shih-Ting Tsao, Yuchen Liu, Wei Zhu, William B. Slayton, Jan S. Moreb, Lujia Dong and Lung-Ji Chang*


View Abstract View on PubMed



Circular RNAs Serve as Novel Biomarkers and Therapeutic Targets in Cancers


Shuai Fang, Jinchang Pan, Chengwei Zhou, Hui Tian, Jinxian He, Weiyu Shen, Xiaofeng Jin, Xiaodan Meng, Nan Jiang and Zhaohui Gong*


View Abstract View on PubMed



Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Editor's Choice

Neuroprotection by Human Dental Pulp Mesenchymal Stem Cells: From Billions to Nano

, 2018; 18(5): 307 - 323

Chaitra Venugopal, Shobha K, Kiranmai S. Rai, Venkata Bharatkumar Pinnelli, Bindu M. Kutty and Anandh Dhanushkodi*


DOI: 10.2174/1566523218666180913152615




Gene Therapy to Enhance Bone and Cartilage Repair in Orthopaedic Surgery

, 2018; 18(3): 154 - 170

Sofia Bougioukli, Christopher H. Evans, Ram K. Alluri, Steven C. Ghivizzani and Jay R. Lieberman*


DOI: 10.2174/1566523218666180410152842






A New Era for Hemoglobinopathies: More Than One Curative Option

, 2017; 17(5): 364 - 378

Nikoletta Psatha, Penelope-Georgia Papayanni and Evangelia Yannaki*


DOI: 10.2174/1566523218666180119123655






Open Access Articles

Clinical Observation of Patients with Leber’s Hereditary Optic Neuropathy Before Gene Therapy

, 2018; 18(6): 386 - 392

Jiajia Yuan, Yong Zhang, Hongli Liu, Zhen Tian, Xin Li, Yichen Zheng, Qin Gao, Lin Song, Xiao Xiao, Jian Sun, Zhitao Wang and Bin Li*




Clinical-Grade Oncolytic Adenovirus Purification Using Polysorbate 20 as an Alternative for Cell Lysis

, 2018; 18(6): 366 - 374

Mafalda G. Moleirinho, Sara Rosa, Manuel J.T. Carrondo*, Ricardo J.S. Silva, Åsa Hagner-McWhirter, Gustaf Ahlén, Mats Lundgren, Paula M. Alves and Cristina Peixoto




Emerging Therapeutic Approaches for Diamond Blackfan Anemia

, 2018; 18(6): 327 - 335

Anna Aspesi*, Chiara Borsotti and Antonia Follenzi*




EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs

, 2018; 18(5): 275 - 285

Yan Wang, Yinping Xie, Lili Li, Yuan He, Di Zheng, Pengcheng Yu, Ling Yu, Lixu Tang, Yibin Wang* and Zhihua Wang*




Human Disease System Biology

, 2018; 18(5): 255 - 256

Liang Cheng and Yang Hu




Oncolytic Virotherapy for Breast Cancer Treatment

, 2018; 18(4): 192 - 205

Samia M. O`Bryan and J. Michael Mathis*




Genetics and Therapies for GM2 Gangliosidosis

, 2018; 18(2): 68 - 89

Maria Begona Cachon-Gonzalez*, Eva Zaccariotto and Timothy Martin Cox




Functional Improvement of Chimeric Antigen Receptor Through Intrinsic Interleukin-15Rα Signaling

, 2018; 18: 1 - 14 (E-Pub Ahead of Print)

Sushmita Nair, Jing-Bo Wang, Shih-Ting Tsao, Yuchen Liu, Wei Zhu, William B. Slayton, Jan S. Moreb, Lujia Dong and Lung-Ji Chang*





The Progress of Gene Therapy for Leber's Optic Hereditary Neuropathy

, 2017; 17(4): 320 - 326

Yong Zhang, Zhen Tian, Jiajia Yuan, Chang Liu, Hong li Liu, Si Qi Ma and Bin Li*





Tet-On Systems For Doxycycline-inducible Gene Expression

, 2016; 16(3): 156 - 167

Atze T. Das, Liliane Tenenbaum and Ben Berkhout




Gene Electrotransfer: A Mechanistic Perspective

, 2016; 16(2): 98 - 129

Christelle Rosazza, Sasa Haberl Meglic, Andreas Zumbusch, Marie-Pierre Rols and Damijan Miklavcic




Building A New Treatment For Heart Failure-Transplantation of Induced Pluripotent Stem Cell-derived Cells into the Heart

, 2016; 16(1): 5 - 13

Shigeru Miyagawa, Satsuki Fukushima, Yukiko Imanishi, Takuji Kawamura, Noriko Mochizuki- Oda, Shigeo Masuda and Yoshiki Sawa




A Simple High Efficiency Intra-Islet Transduction Protocol Using Lentiviral Vectors

, 2015; 15(4): 436 - 446

Carmen Maria Jimenez-Moreno, Irene de Gracia Herrera-Gomez, Livia Lopez-Noriega, Petra Isabel Lorenzo, Nadia Cobo-Vuilleumier, Esther Fuente-Martin, Jose Manuel Mellado-Gil, Geraldine Parnaud, Domenico Bosco, Benoit Raymond Gauthier and Alejandro Martin-Montalvo





Most Cited Articles

Gene Electrotransfer: A Mechanistic Perspective

, 2016; 16(2): 98-129.

Christelle Rosazza, Sasa Haberl Meglic, Andreas Zumbusch, Marie-Pierre Rols and Damijan Miklavcic


DOI: 10.2174/1566523216666160331130040



Building A New Treatment For Heart Failure-Transplantation of Induced Pluripotent Stem Cell-derived Cells into the Heart

, 2016; 16(1): 5-13.

Shigeru Miyagawa, Satsuki Fukushima, Yukiko Imanishi, Takuji Kawamura, Noriko Mochizuki- Oda, Shigeo Masuda and Yoshiki Sawa


DOI: 10.2174/1566523216666160119094143


Lessons Learned from Two Decades of Clinical Trial Experience in Gene Therapy for Fanconi Anemia

, 2016; 16(5): 338-348.

Jennifer E. Adair, Julian Sevilla, Cristina Diaz de Heredia, Pamela S. Becker, Hans-Peter Kiem and Juan Bueren


DOI: 10.2174/1566523217666170119113029







Cell Compatibility of an Eposimal Vector Mediated by the Characteristic Motifs of Matrix Attachment Regions

, 2016; 16(4): 271-277.

Tian-Yun Wang, Li Wang, Yu-Xin Yang, Chun-Peng Zhao, Yan-Long Jia, Qin Li, Jun-He Zhang, Yi-You Peng, Miao Wang, Hong-Yan Xu and Xiao-Yin Wang


DOI: 10.2174/1566523216666161202160936



Most Accessed Articles


EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs

, 2018; 18(5): 275-285.

Yan Wang, Yinping Xie, Lili Li, Yuan He, Di Zheng, Pengcheng Yu, Ling Yu, Lixu Tang, Yibin Wang* and Zhihua Wang*


DOI: 10.2174/1566523218666181008125010




Design of Artificial Immunogens Containing Melanoma-associated T-cell Epitopes

, 2018; 18(6): 375-385.

E.A. Borobova*, D.V. Antonets, E.V. Starostina, L.I. Karpenko, A.A. Ilyichev and S.I. Bazhan


DOI: 10.2174/1566523218666181113112829


Clinical-Grade Oncolytic Adenovirus Purification Using Polysorbate 20 as an Alternative for Cell Lysis

, 2018; 18(6): 366-374.

Mafalda G. Moleirinho, Sara Rosa, Manuel J.T. Carrondo*, Ricardo J.S. Silva, Åsa Hagner-McWhirter, Gustaf Ahlén, Mats Lundgren, Paula M. Alves and Cristina Peixoto


DOI: 10.2174/1566523218666181109141257


Nonviral Delivery Systems for Cancer Gene Therapy: Strategies and Challenges

, 2018; 18(1): 3-20.

Gayong Shim*, Dongyoon Kim, Quoc-Viet Le, Gyu Thae Park, Taekhyun Kwon and Yu-Kyoung Oh*


DOI: 10.2174/1566523218666180119121949



ExomiRs: A Novel Strategy in Cancer Diagnosis and Therapy

, 2018; 18(6): 336-350.

Gilar Gorji-Bahri, Atieh Hashemi* and Hamid Reza Moghimi


DOI: 10.2174/1566523218666181017163204


Biosafety of Recombinant Adeno-associated Virus Vectors

, 2013; 13(6): 434-452.

David J. Dismuke, Liliane Tenenbaum and R. Jude Samulski


DOI: 10.2174/15665232113136660007



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