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"Modern drug discovery is increasingly driven by scientific integration, the ability to pull together seemingly unrelated branches of basic and applied sciences to produce in a timely fashion innovative and efficacious solutions to multidisciplinary human health problems. The editorial staff is to be congratulated for providing a superb forum for publishing such science and the many and varied new directions that challenge how we think about and address drug discovery."

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Forthcoming Special Issues

Discovery and Development of New Anti-infectives: Perspectives and Prospectives


Guest Editor(s): Vijay Kothari
Tentative Publication Date: April, 2019
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Herbal Drugs: Expanding Horizons of Contemporary Therapeutics


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Thiazole Heterocycle: A Privileged Scaffold for Drug Design and Discovery


Current Drug Discovery Technologies, Volume 15, Number 03
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Current Drug Discovery Technologies

,

Volume 15

-

Number 4



Biography   Open Access



Review Article



Review Article

An Evidence-based Review of Medicinal Herbs for the Treatment of Gastroesophageal Reflux Disease (GERD)

, 15(4): 305 - 314

Ayda Hosseinkhani, Kamran Bagheri Lankarani, Abdolali Mohagheghzadeh, Chunlin Long and Mehdi Pasalar*


DOI: 10.2174/1570163814666171010113517




Research Article

Molecular Docking, Synthesis and Biological Evaluation of Sulphonylureas/ Guanidine Derivatives as Promising Antidiabetic Agent

, 15(4): 315 - 325

Ishan I. Panchal*, Dhrubo Jyoti Sen, Ashish D. Patel, Umang Shah, Mehul Patel, Archana Navale and Vashisth Bhavsar


DOI: 10.2174/1570163814666171002102904




Research Article



Research Article   Open Access

The Development of New Factor Xa Inhibitors Based on Amide Synthesis

, 15(4): 335 - 350

Dmitry N. Tarasov, Dmitry G. Tovbin, Dmitry V. Malakhov, Arseniy V. Aybush, Natalia A. Tserkovnikova, Marina I. Savelyeva, Dmitry A. Sychev, Natalia N. Drozd* and Alla Y. Savchenko


DOI: 10.2174/1570163815666180215114732




Research Article



Acknowledgement   Open Access



Articles Ahead of Print









Current Discovery Progress of Some Emerging Anti-infective Chalcones: Highlights from 2016 to 2017


Debarshi Kar Mahapatra , Soumajit Ghorai , Sanjay Kumar Bharti, Asmita Gajbhiye Patil* and Shovanlal Gayen


View Abstract View on PubMed


Efficacy of a Herbal Formulation Based on Foeniculum Vulgare in Oligo/Amenorrhea: A Randomized Clinical Trial


Farnoush Falahat, Sedigheh Ayatiafin, Lida Jarahi, Roshanak Mokaberinejad, Hasan Rakhshandeh, Zohre Feyzabadi* and Mandana Tavakkoli


View Abstract View on PubMed


Abstracts Ahead of Print

An herbal H2 blocker in melasma treatment


Marjan Mahjour* and Arash Khoushabi


View Abstract




Novel approaches to anti-atherosclerotic therapy: Cell-based models and herbal preparations (Review of our own data)


Alexander N. Orekhov*, Andrey V. Grechko, Elena B. Romanenko, Dongwei Zhang and Dimitry A. Chistiakov


View Abstract


PCSK9 inhibitors and cardiovascular disease: impact on cardiovascular outcomes


Paraskevi Farmaki, Christos Damaskos, Nikolaos Garmpis, Anna Garmpi, Spyridon Savvanis and Evangelos Diamantis*


View Abstract


Efficacy of β-D-mannuronic acid [M2000] on pro-apoptotic process and inflammatory related molecules NFҡB, IL-8 and Cd49d using healthy donor PBMC


Atousa Khalatbari, Mehdi Mahdavi, Fahimeh Jafarnezhad, Sanaz Afraei, Farzaneh Tofighi Zavareh, Zahra Aghazadeh, Afshin Ghaderi and Abbas Mirshafiey*


View Abstract





Chemistry And Pharmacological Activities Of Biginelli Product- A Brief Overview


Namy George, M Asha Asokan, A Ajish, M Surya, V Vishnu, Rajasree G Pai and Subin Mary Zachariah*


View Abstract


Editor's Choice

Molecular Docking, Synthesis and Biological Evaluation of Sulphonylureas/ Guanidine Derivatives as Promising Antidiabetic Agent

, 2018; 15(4): 315 - 325

Ishan I. Panchal*, Dhrubo Jyoti Sen, Ashish D. Patel, Umang Shah, Mehul Patel, Archana Navale and Vashisth Bhavsar


DOI: 10.2174/1570163814666171002102904





Affinity Crystallography Reveals the Bioactive Compounds of Industrial Juicing Byproducts of Punica granatum for Glycogen Phosphorylase

, 2018; 15(1): 41 - 53

George A. Stravodimos, Anastassia L. Kantsadi, Anna Apostolou, Efthimios Kyriakis, Vassiliki-Nafsika Kafaski-Kanelli, Theodora Solovou, Pagona Gatzona, Panagiota G.V. Liggri, Stavroula Theofanous, Vyron A. Gorgogietas, Apostolia Kissa, Chariklia Psachoula, Angelos Lemonakis, Demetra S.M. Chatzileontiadou, Anna-Maria G. Psarra, Vassiliki T. Skamnaki, Serkos A. Haroutounian* and Demetres. D. Leonidas*


DOI: 10.2174/1570163814666170619091736






QSAR Studies, Synthesis and Antibacterial Assessment of New Inhibitors Against Multidrug-Resistant Mycobacterium tuberculosis

, 2017; 14(1): 25 - 38

Vasyl Kovalishyn, Volodymyr Brovarets, Volodymyr Blagodatnyi, Iryna Kopernyk, Diana Hodyna, Svitlana Chumachenko, Oleg Shablykin, Oleksandr Kozachenko, Myhailo Vovk, Marianna Barus, Myhailo Bratenko and Larysa Metelytsia


DOI: 10.2174/1570163813666161108125227





Open Access Articles

The Development of New Factor Xa Inhibitors Based on Amide Synthesis

, 2018; 15(4): 335 - 350

Dmitry N. Tarasov, Dmitry G. Tovbin, Dmitry V. Malakhov, Arseniy V. Aybush, Natalia A. Tserkovnikova, Marina I. Savelyeva, Dmitry A. Sychev, Natalia N. Drozd* and Alla Y. Savchenko




Molecular Docking, Synthesis and Biological Evaluation of Sulphonylureas/ Guanidine Derivatives as Promising Antidiabetic Agent

, 2018; 15(4): 315 - 325

Ishan I. Panchal*, Dhrubo Jyoti Sen, Ashish D. Patel, Umang Shah, Mehul Patel, Archana Navale and Vashisth Bhavsar




The Modulatory Effect of Lead Drug Candidates on Inflammatory Gene Expression in Sepsis: A Mini-Review

, 2018; 15: 1 - 11 (E-Pub Ahead of Print)

Samuel Mawuli Adadey*, Michael Bright Yakass, Seth Agyemang and Samuel Duodu




Date Palm (Phoenix dactylifera): Novel Findings and Future Direc-tions for Food and Drug Discovery

, 2018; 15: 1 - 11 (E-Pub Ahead of Print)

Ali H. El-Far*, Babatunji Emmanuel Oyinloye, Masood Sepehrimanesh, Mahmoud A. Gab Allah, Ibrahim Abu Reidah, Hazem M. Shaheen, Iman Razeghian-Jahromi, Abd el-wahab A. Alsenosy, Ahmed E. Noreldin, Soad K. Al Jaouni and Shaker A. Mousa




Structure based docking studies of GLUT4 towards exploring selected phytochemicals from Solanum xanthocarpum as a therapeutic target for the treatment of cancer

, 2018; 15: 1 - 10 (E-Pub Ahead of Print)

Babatunji Emmanuel Oyinloye*, Tayo Alex Adekiya, Raphael Taiwo Aruleba, Oluwafemi Adeleke Ojo and Basiru Olaitan Ajiboye






Can EGFR-Tyrosine Kinase Inhibitors (TKI) Alone Without Talc Pleurodesis Prevent Recurrence of Malignant Pleural Effusion (MPE) in Lung Adenocarcinoma

, 2016; 13(2): 68 - 76

Akash Verma, Akhil Chopra, Yeo W. Lee, Lavina D. Bharwani, Atasha B. Asmat, Dokeu B.A Aneez, Fazuludeen A. Akbar, Albert Y.H. Lim, Sanjay H. Chotirmall and John Abisheganaden




Quantitative Structure-Cytotoxic Activity Relationship 1-(Benzoyloxy)urea and Its Derivative

, 2016; 13(2): 101 - 108

Suko Hardjono, Siswandono Siswodihardjo, Purwanto Pramono and Win Darmanto









Most Cited Articles





Can EGFR-Tyrosine Kinase Inhibitors (TKI) Alone Without Talc Pleurodesis Prevent Recurrence of Malignant Pleural Effusion (MPE) in Lung Adenocarcinoma

, 2016; 13(2): 68-76.

Akash Verma, Akhil Chopra, Yeo W. Lee, Lavina D. Bharwani, Atasha B. Asmat, Dokeu B.A Aneez, Fazuludeen A. Akbar, Albert Y.H. Lim, Sanjay H. Chotirmall and John Abisheganaden


DOI: 10.2174/1570163813666160524142846




Phytochemistry and Phytotherapeutic Aspects of Elaeagnus angustifolia L.

, 2016; 13(4): 199-210.

Farid Niknam, Amir Azadi, Alireza Barzegar, Pouya Faridi, Nader Tanideh and Mohammad M. Zarshenas


DOI: 10.2174/1570163813666160905115325





Most Accessed Articles


Compound Libraries: Recent Advances and Their Applications in Drug Discovery

, 2017; 14(4): 216-228.

Zhen Gong, Guoping Hu, Qiang Li, Zhiguo Liu, Fei Wang, Xuejin Zhang, Jian Xiong, Peng Li, Yan Xu, Rujian Ma, Shuhui Chen and Jian Li*


DOI: 10.2174/1570163814666170425155154


The Development of New Factor Xa Inhibitors Based on Amide Synthesis

, 2018; 15(4): 335-350.

Dmitry N. Tarasov, Dmitry G. Tovbin, Dmitry V. Malakhov, Arseniy V. Aybush, Natalia A. Tserkovnikova, Marina I. Savelyeva, Dmitry A. Sychev, Natalia N. Drozd* and Alla Y. Savchenko


DOI: 10.2174/1570163815666180215114732


Hair Growth: Focus on Herbal Therapeutic Agent

, 2015; 12(1): 21-42.

Satish Patel, Vikas Sharma, Nagendra S. Chauhan, Mayank Thakur and V.K. Dixit


DOI: 10.2174/1570163812666150610115055








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