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Current Drug Discovery Technologies

Volume 16, 4 Issues, 2019
ISSN: 1875-6220 (Online)
ISSN: 1570-1638 (Print)
This journal supports open access

Aims & Scope

Due to the plethora of new approaches being used in modern drug discovery by the pharmaceutical industry, Current Drug Discovery Technologies has been established to provide comprehensive overviews of all the major modern techniques and technologies used in drug design and discovery. The journal is the forum for publishing original research papers, full-length/mini reviews, drug clinical trial studies and guest edited thematic issues describing novel approaches and cutting edge technologies used in all stages of drug discovery. The journal addresses the multidimensional challenges of drug discovery science including integration issues of the drug discovery process.

Current Drug Discovery Technologies is an essential journal for all scientists and research managers involved in drug discovery who wish to keep abreast of all the modern techniques and technologies used in drug discovery.

Current Drug Discovery Technologies

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Volume 16

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Number 3



Biography   Open Access



Review Article

Quality by Design: Concept to Applications

, 16(3): 240 - 250

Suryakanta Swain*, Rabinarayan Parhi, Bikash Ranjan Jena and Sitty Manohar Babu


DOI: 10.2174/1570163815666180308142016


Review Article



Review Article



Research Article

Effect of β-D-Mannuronic Acid (M2000) on Oxidative Stress Enzymes’ Gene Using Healthy Donor Peripheral Blood Mononuclear Cells for Evaluating the Anti-Aging Property

, 16(3): 265 - 271

Mahsa Taeb, Abdollah Jafarzadeh*, Seyed Shahabeddin Mortazavi-Jahromi, Nahid Zainodini, Mohammad Reza Mirzaei, Fahimeh Jafarnezhad-Ansariha, Zahra Aghazadeh and Abbas Mirshafiey*


DOI: 10.2174/1570163815666180515122834


Research Article



Research Article

β-cell Regenerative Potential of Selected Herbal Extracts in Alloxan Induced Diabetic Rats

, 16(3): 278 - 284

Anoja Priyadarshani Attanayake*, Kamani Ayoma Perera Wijewardana Jayatilaka, Lakmini Kumari Boralugoda Mudduwa and Chitra Pathirana


DOI: 10.2174/1570163815666180418153024


Research Article



Articles Ahead of Print




Kaempferol as a Potential PAK4 Inhibitor in Triple Negative Breast Cancer: Extra Precision Glide Docking and Free Energy Calculation


Michael A. Arowosegbe*, Oluwamuyiwa T. Amusan, Segun A. Adeola, Oluwatosin B. Adu, Israel A. Akinola, Bimpe F. Ogungbe, Olaposi I. Omotuyi, Gbemisola M. Saibu, Adewale J. Ogunleye, Ramon I. Kanmodi, Nekabari E. Lugbe, Oluwafemi J. Ogunmola, Damilola C. Ajayi, Sedoten O. Ogun, Faith O. Oyende, Ahmed O. Bello, Abudulmalik O. Ishola and Patrick E. Obasieke


DOI: 10.2174/1570163816666190823135948
View Abstract View on PubMed


Exploring Antimicrobials from the Flora and Fauna of Marine: Opportunities and Limitations


Krishanmoorthy Venkateskumar, Subramani Parasuraman*, Leow Yu Chuen, Veerasamy Ravichandran and Subramani Balamurgan


DOI: 10.2174/1570163816666190819141344
View Abstract View on PubMed





Discovery and Development of Novel Anti-fungal Peptides Against Foodspoiling Fungi


Belal J. Muhialdin*, Hussein L. Algboory, Nameer K. Mohammed, Hana Kadum, Anis Shobirin Meor Hussin, Nazamid Saari and Zaiton Hassan


DOI: 10.2174/1570163816666190715120038
View Abstract View on PubMed


Interaction with Modified Cyclodextrin as a Way to Increase the Antimalarial Activity of Primaquine


Liliane Henrique Torres, Lucas Bragança de Carvalho, Adneia de Fátima Abreu Venceslau, Carlos Jaime and Luciana de Matos Alves Pinto*


DOI: 10.2174/1570163816666190719154258
View Abstract


Abstracts Ahead of Print

Published Contents

Editor's Choice




Molecular Docking, Synthesis and Biological Evaluation of Sulphonylureas/ Guanidine Derivatives as Promising Antidiabetic Agent

, 2018; 15(4): 315 - 325

Ishan I. Panchal*, Dhrubo Jyoti Sen, Ashish D. Patel, Umang Shah, Mehul Patel, Archana Navale and Vashisth Bhavsar


DOI: 10.2174/1570163814666171002102904





Affinity Crystallography Reveals the Bioactive Compounds of Industrial Juicing Byproducts of Punica granatum for Glycogen Phosphorylase

, 2018; 15(1): 41 - 53

George A. Stravodimos, Anastassia L. Kantsadi, Anna Apostolou, Efthimios Kyriakis, Vassiliki-Nafsika Kafaski-Kanelli, Theodora Solovou, Pagona Gatzona, Panagiota G.V. Liggri, Stavroula Theofanous, Vyron A. Gorgogietas, Apostolia Kissa, Chariklia Psachoula, Angelos Lemonakis, Demetra S.M. Chatzileontiadou, Anna-Maria G. Psarra, Vassiliki T. Skamnaki, Serkos A. Haroutounian* and Demetres. D. Leonidas*


DOI: 10.2174/1570163814666170619091736






Open Access Articles

The Modulatory Effect of Lead Drug Candidates on Inflammatory Gene Expression in Sepsis: A Mini-Review

, 2019; 16(1): 48 - 56

Samuel Mawuli Adadey*, Michael Bright Yakass, Seth Agyemang and Samuel Duodu




Date Palm (Phoenix dactylifera): Novel Findings and Future Directions for Food and Drug Discovery

, 2019; 16(1): 2 - 10

Ali H. El-Far*, Babatunji E. Oyinloye, Masood Sepehrimanesh, Mahmoud A. Gab Allah, Ibrahim Abu-Reidah, Hazem M. Shaheen, Iman Razeghian-Jahromi, Abd el-wahab A. Alsenosy, Ahmed E. Noreldin, Soad K. Al Jaouni and Shaker A. Mousa*




The Development of New Factor Xa Inhibitors Based on Amide Synthesis

, 2018; 15(4): 335 - 350

Dmitry N. Tarasov, Dmitry G. Tovbin, Dmitry V. Malakhov, Arseniy V. Aybush, Natalia A. Tserkovnikova, Marina I. Savelyeva, Dmitry A. Sychev, Natalia N. Drozd* and Alla Y. Savchenko




Structure-Based Docking Studies of GLUT4 Towards Exploring Selected Phytochemicals from Solanum xanthocarpum as a Therapeutic Target for the Treatment of Cancer

, 2018; 15: 1 - 10 (E-Pub Ahead of Print)

Babatunji Emmanuel Oyinloye*, Tayo Alex Adekiya, Raphael Taiwo Aruleba, Oluwafemi Adeleke Ojo and Basiru Olaitan Ajiboye






Can EGFR-Tyrosine Kinase Inhibitors (TKI) Alone Without Talc Pleurodesis Prevent Recurrence of Malignant Pleural Effusion (MPE) in Lung Adenocarcinoma

, 2016; 13(2): 68 - 76

Akash Verma, Akhil Chopra, Yeo W. Lee, Lavina D. Bharwani, Atasha B. Asmat, Dokeu B.A Aneez, Fazuludeen A. Akbar, Albert Y.H. Lim, Sanjay H. Chotirmall and John Abisheganaden




Quantitative Structure-Cytotoxic Activity Relationship 1-(Benzoyloxy)urea and Its Derivative

, 2016; 13(2): 101 - 108

Suko Hardjono, Siswandono Siswodihardjo, Purwanto Pramono and Win Darmanto









Most Cited Articles

Research Article

Immunomodulatory effect of G2013 (α-L-guluronic acid) on the TLR2 and TLR4 in human mononuclear cells

, 2018; 15(2): 123-131.

Laleh Sharifi, Monireh Mohsenzadegan, Asghar Aghamohammadi*, Nima Rezaei, Farzaneh Tofighi Zavareh, Saied Bokaie, Mona Moshiri, Zahra Aghazadeh, Zahra Norouzbabaie, Gholamreza Azizi and Abbas Mirshafiey*


DOI: 10.2174/1570163814666170605111331


Review Article

Update on nitazoxanide: A multifunctional chemotherapeutic agent

, 2018; 15(3): 201-213.

Anshul Shakya*, Hans Raj Bhat and Surajit Kumar Ghosh


DOI: 10.2174/1570163814666170727130003




Review Article

A retrospect study on thiazole derivatives as the potential antidiabetic agents in drug discovery and developments

, 2018; 15(3): 163-177.

Gopal L. Khatik*, Ashok Kumar Datusalia, Waquar Ahsan, Paranjeet Kaur, Manish Vyas, Amit Mittal and Surendra Kumar Nayak


DOI: 10.2174/1570163814666170915134018


Review Article

Thiazole containing heterocycles with CNS activity

, 2018; 15(3): 178-195.

Shikha Agarwal*, Priyanka Kalal, Divyani Gandhi and Prakash Prajapat


DOI: 10.2174/1570163814666170724170152


Review Article

Anti-carcinogenic effects of carnosol-an updated review

, 2018; 15(1): 32-40.

Saeed Samarghandian, Mohsen Azimi-Nezhad and Tahereh Farkhondeh*


DOI: 10.2174/1570163814666170413121732


Systemic Review Article

A systematic review on popularity, application and characteristics of protein secondary structure prediction tools

, 2019; 16(2): 159-172.

Elaheh Kashani-Amin, Ozra Tabatabaei-Malazy, Amirhossein Sakhteman, Bagher Larijani and Azadeh Ebrahim-Habibi*


DOI: 10.2174/1570163815666180227162157


Review Article

Quinoline, coumarin and other heterocyclic analogs based HIV-1 integrase inhibitors

, 2018; 15(1): 2-19.

Pankaj Wadhwa, Priti Jain, Santosh Rudrawar and Hemant R.A. Jadhav*


DOI: 10.2174/1570163814666170531115452


Review Article

Multifaceted effects of delta opioid receptors and dadle in diseases of the nervous system

, 2018; 15(2): 94-108.

Jea-Young Lee, M. Grant Liska, Marci Crowley, Kaya Xu, Sandra A. Acosta, Cesar V. Borlongan* and Vivian A. Guedes


DOI: 10.2174/1570163814666171010114403



Review Article

Review on synthetic chemistry and antibacterial importance of thiazole derivatives

, 2018; 15(3): 214-228.

Ankita Kashyap, Nayana Adhikari, Arpita Das, Anshul Shakya, Surajit Kumar Ghosh, Udaya Pratap Singh and Hans Raj Bhat*


DOI: 10.2174/1570163814666170911144036



Review Article

Critical insight into the design of PPAR-γ agonists by virtual screening techniques

, 2019; 16(1): 82-90.

Neelaveni Thangavel*, Mohammed Al Bratty, Sadique Akhtar Javed, Waquar Ahsan and Hassan A. Alhazmi


DOI: 10.2174/1570163815666180227164028


Review Article

Date palm (Phoenix dactylifera): Novel findings and future directions for food and drug discovery

, 2019; 16(1): 2-10.

Ali H. El-Far*, Babatunji E. Oyinloye, Masood Sepehrimanesh, Mahmoud A. Gab Allah, Ibrahim Abu-Reidah, Hazem M. Shaheen, Iman Razeghian-Jahromi, Abd el-wahab A. Alsenosy, Ahmed E. Noreldin, Soad K. Al Jaouni and Shaker A. Mousa*


DOI: 10.2174/1570163815666180320111937



Most Accessed Articles


The Hepato-protective Effects of Portulaca oleracea L. extract: Review

, 2019; 16(2): 122-126.

Tahereh Farkhondeh, Saeed Samarghandian*, Mohsen Azimi-Nezhad and Soroush Hozeifi


DOI: 10.2174/1570163815666180330142724


Molecular Docking in Formulation and Development

, 2019; 16(1): 30-39.

Tejinder Kaur*, Ashwini Madgulkar, Mangesh Bhalekar and Kalyani Asgaonkar


DOI: 10.2174/1570163815666180219112421


Efficacy of Aloe vera/ Plantago Major Gel in Diabetic Foot Ulcer: A Randomized Double-Blind Clinical Trial

, 2019; 16(2): 223-231.

Younes Najafian, Zahra M. Khorasani, Mona N. Najafi, Shokouh S. Hamedi, Marjan Mahjour and Zohre Feyzabadi*


DOI: 10.2174/1570163815666180115093007



A Systematic Review on Popularity, Application and Characteristics of Protein Secondary Structure Prediction Tools

, 2019; 16(2): 159-172.

Elaheh Kashani-Amin, Ozra Tabatabaei-Malazy, Amirhossein Sakhteman, Bagher Larijani and Azadeh Ebrahim-Habibi*


DOI: 10.2174/1570163815666180227162157



Chemistry and Pharmacological Activities of Biginelli Product- A Brief Overview

, 2019; 16(2): 127-134.

Namy George, Asha Asokan Manakkadan, Ajish Ariyath, Surya Maniyamma, Vishnu Vijayakumar, Rajasree G. Pai and Subin Mary Zachariah*


DOI: 10.2174/1570163815666180807141922






Editor-in-Chief

Vladimir P. Torchilin
(44972 citations)
Department of Pharmaceutical Science Center for Pharmaceutical Biotechnology and Nanomedicine
Northeastern University
Boston, MA 02115
USA

Biography View Full Editorial Board

Journal History

Current Drug Discovery Technologies Journal was launched in 2004. Dr. Vladimir P. Torchilin serves as the Editor-in-Chief of the journal.
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