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Current Drug Discovery Technologies

Volume 18, 6 Issues, 2021
ISSN: 1875-6220 (Online)
ISSN: 1570-1638 (Print)
This journal supports open access

Aims & Scope

Due to the plethora of new approaches being used in modern drug discovery by the pharmaceutical industry, Current Drug Discovery Technologies has been established to provide comprehensive overviews of all the major modern techniques and technologies used in drug design and discovery. The journal is the forum for publishing original research papers, full-length/mini reviews, drug clinical trial studies and guest edited thematic issues describing novel approaches and cutting edge technologies used in all stages of drug discovery. The journal addresses the multidimensional challenges of drug discovery science including integration issues of the drug discovery process.

Current Drug Discovery Technologies is an essential journal for all scientists and research managers involved in drug discovery who wish to keep abreast of all the modern techniques and technologies used in drug discovery.

Current Drug Discovery Technologies

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Volume 18

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Number 5









Research Article

Identification of Main Protease of Coronavirus SARS-CoV-2 (Mpro) Inhibitors from Melissa officinalis

, 18(5): e17092020186048

Olusola O. Elekofehinti*, Opeyemi Iwaloye, Courage D. Famusiwa, Olanrewaju Akinseye and Joao B. T. Rocha


DOI: 10.2174/1570163817999200918103705


Research Article

Assessment of Biochemical Determinants in Multiple Sclerosis Patients Following the Oral Administration of β-D-Mannuronic Acid (M2000)

, 18(5): e17092020186049

Mohamad Reza Nikouei Moghaddam, Monireh Movahedi, Maryam Bananej, Soheil Najafi, Nahid Beladi Moghadam, Payam Saadat, Fariba Mokhtarian and Abbas Mirshafiey*


DOI: 10.2174/1570163817999200918104333


Research Article

Synthesis and Study of Some 17a-aza-D-homo Steroids as 5α-Reductase Inhibitors

, 18(5): e22092020186180

Priyanka Rana, Neelima Dhingra*, Poonam Arora, Richa Dhingra, Chauhan Monika and Ankit Gupta


DOI: 10.2174/1570163817666200922120406


Research Article





Current Drug Discovery Technologies, Volume 19 (2022) - Number 1


This issue is in progress but contains articles that are final and fully citable.

Current Drug Discovery Technologies, Volume 19 (2022) - Number 6


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print



Drug Repositioning: A Unique Approach to Refurbish Drug Discovery


Mayura A Kale*, Prashant B Shamkuwar, Vishnukant K Mourya, Aishwarya B Deshpande and Priyanka A Shelke


DOI: 10.2174/1570163818666210316114331
View Abstract View on PubMed





Prunella vulgaris L: Critical Pharmacological, Expository Traditional Uses and Extensive Phytochemistry: A Review


Reyaz Hassan Mir, Mohammad Faizan Bhat, Gifty Sawhney, Parveen Kumar, Nusrit Iqbal Andrabi, Majeed Shaikh, Roohi Mohi-ud-Din and Mubashir Hussain Masoodi*


DOI: 10.2174/1570163818666210203181542
View Abstract View on PubMed



The Potential Role of Green Tea and its Main Constituent (Epigallocatechin -3-Gallate) in Pain Relief: A Mechanistic Review


Sajad Sahab Negah, Hamed Ghazavi, Farzaneh Vafaee, Roghayeh Rashidi, Ahmad Reza Aminian and Fatemeh Forouzanfar*


DOI: 10.2174/1570163817666201229121033
View Abstract View on PubMed


ACE2 as a Potential Target for Management of Novel Coronavirus (nCoV- 2019)


Elham Foroozanfar, Mohamad Forouzanfar, Tahereh Farkhondeh, Saeed Samarghandian and Fatemeh Forouzanfar*


DOI: 10.2174/1570163817999201228215911
View Abstract View on PubMed


Published Contents

Editor's Choice

The Effect of Myrtus communis Aqueous Extract-Containing Gel on Wound Healing in Streptozotocin-Induced Diabetic Rats

, 2021; 18(4): 542 - 547

Seyed-Ali Khodaie, Fatemeh Emadi, Mohsen Naseri*, Mohammad Kamalinejad, Seyed Mohammad Riahi, Fatemeh Alijaniha and Mehrdad Roghani*


DOI: 10.2174/1570163817666200712163956







Identification and Ranking of Clinical Compounds with Activity Against Log-phase Growing Uropathogenic Escherichia coli

, 2020; 17(2): 191 - 196

Hongxia Niu, Rebecca Yee, Peng Cui, Shuo Zhang, Lili Tian, Wanliang Shi, David Sullivan, Bingdong Zhu, Wenhong Zhang and Ying Zhang *


DOI: 10.2174/1570163815666180808115501







Open Access Articles

The Development of New Low-Molecular-Weight Factor Xa Inhibitors that are Potential Anticoagulants

, 2022; 19(1): 2 - 9

Dmitry G. Tovbin, Dmitry N. Tarasov, Dmitry V. Malakhov, Natalia A. Tserkovnikova, Arseniy V. Aybush and Natalia N. Drozd*






Molecular Context of ADP-ribosylation in Schistosomes for Drug Discovery and Vaccine Development

, 2021; 18(4): 473 - 484

Amandla Chutshela, Priscilla Masamba, Babatunji Emmanuel Oyinloye and Abidemi Paul Kappo*





Structure-Based Docking Studies of GLUT4 Towards Exploring Selected Phytochemicals from Solanum xanthocarpum as a Therapeutic Target for the Treatment of Cancer

, 2019; 16(4): 406 - 416

Babatunji Emmanuel Oyinloye*, Tayo Alex Adekiya, Raphael Taiwo Aruleba, Oluwafemi Adeleke Ojo and Basiru Olaitan Ajiboye




The Modulatory Effect of Lead Drug Candidates on Inflammatory Gene Expression in Sepsis: A Mini-Review

, 2019; 16(1): 48 - 56

Samuel Mawuli Adadey*, Michael Bright Yakass, Seth Agyemang and Samuel Duodu




Date Palm (Phoenix dactylifera): Novel Findings and Future Directions for Food and Drug Discovery

, 2019; 16(1): 2 - 10

Ali H. El-Far*, Babatunji E. Oyinloye, Masood Sepehrimanesh, Mahmoud A. Gab Allah, Ibrahim Abu-Reidah, Hazem M. Shaheen, Iman Razeghian-Jahromi, Abd el-wahab A. Alsenosy, Ahmed E. Noreldin, Soad K. Al Jaouni and Shaker A. Mousa*




The Development of New Factor Xa Inhibitors Based on Amide Synthesis

, 2018; 15(4): 335 - 350

Dmitry N. Tarasov, Dmitry G. Tovbin, Dmitry V. Malakhov, Arseniy V. Aybush, Natalia A. Tserkovnikova, Marina I. Savelyeva, Dmitry A. Sychev, Natalia N. Drozd* and Alla Y. Savchenko






Can EGFR-Tyrosine Kinase Inhibitors (TKI) Alone Without Talc Pleurodesis Prevent Recurrence of Malignant Pleural Effusion (MPE) in Lung Adenocarcinoma

, 2016; 13(2): 68 - 76

Akash Verma, Akhil Chopra, Yeo W. Lee, Lavina D. Bharwani, Atasha B. Asmat, Dokeu B.A Aneez, Fazuludeen A. Akbar, Albert Y.H. Lim, Sanjay H. Chotirmall and John Abisheganaden




Quantitative Structure-Cytotoxic Activity Relationship 1-(Benzoyloxy)urea and Its Derivative

, 2016; 13(2): 101 - 108

Suko Hardjono, Siswandono Siswodihardjo, Purwanto Pramono and Win Darmanto







Most Cited Articles

Review Article

The protective effects of green tea catechins in the management of neurodegenerative diseases: A review

, 2019; 16(1): 57-65.

Tahereh Farkhondeh, Hanieh Shaterzadeh Yazdi and Saeed Samarghandian*


DOI: 10.2174/1570163815666180219115453


Review Article

Date palm (Phoenix dactylifera): Novel findings and future directions for food and drug discovery

, 2019; 16(1): 2-10.

Ali H. El-Far*, Babatunji E. Oyinloye, Masood Sepehrimanesh, Mahmoud A. Gab Allah, Ibrahim Abu-Reidah, Hazem M. Shaheen, Iman Razeghian-Jahromi, Abd el-wahab A. Alsenosy, Ahmed E. Noreldin, Soad K. Al Jaouni and Shaker A. Mousa*


DOI: 10.2174/1570163815666180320111937


Review Article

Therapeutic potential of citronella essential oil: A review

, 2019; 16(4): 330-339.

Ruchi Sharma, Rekha Rao*, Sunil Kumar, Sheefali Mahant and Sarita Khatkar


DOI: 10.2174/1570163815666180718095041


General Research Article

Structure-based docking studies of glut4 towards exploring selected phytochemicals from solanum xanthocarpum as a therapeutic target for the treatment of cancer

, 2019; 16(4): 406-416.

Babatunji Emmanuel Oyinloye*, Tayo Alex Adekiya, Raphael Taiwo Aruleba, Oluwafemi Adeleke Ojo and Basiru Olaitan Ajiboye


DOI: 10.2174/1570163815666180801152110


Review Article

Mechanisms of antimicrobial resistance (AMR) and alternative approaches to overcome AMR

, 2020; 17(4): 430-447.

Chew-Li Moo, Shun-Kai Yang, Khatijah Yusoff, Mokrish Ajat, Warren Thomas, Aisha Abushelaibi, Swee-Hua-Erin Lim and Kok-Song Lai*


DOI: 10.2174/1570163816666190304122219



Review Article

Quality by design: Concept to applications

, 2019; 16(3): 240-250.

Suryakanta Swain*, Rabinarayan Parhi, Bikash Ranjan Jena and Sitty Manohar Babu


DOI: 10.2174/1570163815666180308142016



General Research Article

Biopharmaceutical potential of selegiline loaded chitosan nanoparticles in the management of parkinson’s disease

, 2019; 16(4): 417-425.

Rajalakshmi Rukmangathen*, Indira Muzib Yallamalli and Prasanna Raju Yalavarthi


DOI: 10.2174/1570163815666180418144019


Review Article

Towards breast cancer vaccines, progress and challenges

, 2019; 16(3): 251-258.

Javad Behravan*, Atefeh Razazan and Ghazal Behravan


DOI: 10.2174/1570163815666180502164652


Research Article

β-cell regenerative potential of selected herbal extracts in alloxan induced diabetic rats

, 2019; 16(3): 278-284.

Anoja Priyadarshani Attanayake*, Kamani Ayoma Perera Wijewardana Jayatilaka, Lakmini Kumari Boralugoda Mudduwa and Chitra Pathirana


DOI: 10.2174/1570163815666180418153024


General Research Article

Topological analysis of electron density in large biomolecular systems

, 2019; 16(4): 437-448.

Maria A. Grishina and Vladimir A. Potemkin*


DOI: 10.2174/1570163815666180821165330


Review Article

Molecular docking in formulation and development

, 2019; 16(1): 30-39.

Tejinder Kaur Marwaha*, Ashwini Madgulkar, Mangesh Bhalekar and Kalyani Asgaonkar


DOI: 10.2174/1570163815666180219112421


Systemic Review Article

A systematic review on popularity, application and characteristics of protein secondary structure prediction tools

, 2019; 16(2): 159-172.

Elaheh Kashani-Amin, Ozra Tabatabaei-Malazy, Amirhossein Sakhteman, Bagher Larijani and Azadeh Ebrahim-Habibi*


DOI: 10.2174/1570163815666180227162157




Most Accessed Articles

The Development of New Low-Molecular-Weight Factor Xa Inhibitors that are Potential Anticoagulants

, 2022; 19(1): 2-9.

Dmitry G. Tovbin, Dmitry N. Tarasov, Dmitry V. Malakhov, Natalia A. Tserkovnikova, Arseniy V. Aybush and Natalia N. Drozd*


DOI: 10.2174/1568009621666210224104940



Aqueous Extract of Cola nitida and Garcinia kola Synergistically Enhances Hippocampal-hypothalamic Glutamate and Na+ /K+ -ATPase Activity in Male Wistar Rats

, 2022; 19(1): 1-11.

Kehinde S. Olaniyi*, Isaiah W. Sabinari, Adesola A. Oniyide, Nifesimi T. Akinnagbe, Toluwani B. Agunbiade and Oluwole O. Alese


DOI: 10.2174/1570163818666210329102207




Bronchospasmolytic and Adenosine Binding Activity of 8- (Proline / Pyrazole)- Substituted Xanthine Derivatives

, 2021; 18(5): 8-19.

Sneha Singh, Madhwi Ojha, Divya Yadav, Sonja Kachler, Karl-Norbert Klotz and Rakesh Yadav*


DOI: 10.2174/1570163817666200922121005



A Comparative Survey on Antioxidant Activity of Iranian Shrimp Waste (Penaeus semisulcatus) and Synthetic Antioxidants

, 2021; 18(5): 11-16.

Naiema Vakili Saatloo, Leila Peivasteh-Roudsari, Hadi Eghbaljoo gharehgheshlaghi, Gholamreza Jahed Khaniki*, Ramin Nabizadeh Nodehi, Mahmood Alimohammadi and Parisa Sadighara*


DOI: 10.2174/1570163817999201006192141



Synthesis and Study of Some 17a-aza-D-homo Steroids as 5α-Reductase Inhibitors

, 2021; 18(5): 7-24.

Priyanka Rana, Neelima Dhingra*, Poonam Arora, Richa Dhingra, Chauhan Monika and Ankit Gupta


DOI: 10.2174/1570163817666200922120406



Assessment of Biochemical Determinants in Multiple Sclerosis Patients Following the Oral Administration of β-D-Mannuronic Acid (M2000)

, 2021; 18(5): 6-12.

Mohamad Reza Nikouei Moghaddam, Monireh Movahedi, Maryam Bananej, Soheil Najafi, Nahid Beladi Moghadam, Payam Saadat, Fariba Mokhtarian and Abbas Mirshafiey*


DOI: 10.2174/1570163817999200918104333


Identification of Main Protease of Coronavirus SARS-CoV-2 (Mpro) Inhibitors from Melissa officinalis

, 2021; 18(5): 5-19.

Olusola O. Elekofehinti*, Opeyemi Iwaloye, Courage D. Famusiwa, Olanrewaju Akinseye and Joao B. T. Rocha


DOI: 10.2174/1570163817999200918103705



Molecular Context of ADP-ribosylation in Schistosomes for Drug Discovery and Vaccine Development

, 2021; 18(4): 473-484.

Amandla Chutshela, Priscilla Masamba, Babatunji Emmanuel Oyinloye and Abidemi Paul Kappo*


DOI: 10.2174/1570163817666200806170654




Editor-in-Chief

graphic
Vladimir P. Torchilin
(68301 citations)
Department of Pharmaceutical Science Center for Pharmaceutical Biotechnology and Nanomedicine
Northeastern University
Boston, MA 02115
(USA)
Biography
View Full Editorial Board

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Journal History

Current Drug Discovery Technologies Journal was launched in 2004. Dr. Vladimir P. Torchilin serves as the Editor-in-Chief of the journal.
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