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Current Chemical Biology

Volume 16, 4 Issues, 2022
ISSN: 1872-3136 (Online)
ISSN: 2212-7968 (Print)
This journal supports open access

Aims & Scope

Current Chemical Biology aims to publish full-length and mini reviews as well as research papers on exciting new developments at the chemistry-biology interface, covering topics relating to Chemical Synthesis, Science at Chemistry-Biology Interface and Chemical Mechanisms of Biological Systems.

Current Chemical Biology covers the following areas: Chemical Synthesis (Syntheses of biologically important macromolecules including proteins, polypeptides, oligonucleotides, oligosaccharides etc.; Asymmetric synthesis; Combinatorial synthesis; Diversity-oriented synthesis; Template-directed synthesis; Biomimetic synthesis; Solid phase biomolecular synthesis; Synthesis of small biomolecules: amino acids, peptides, lipids, carbohydrates and nucleosides; and Natural product synthesis).

Science at Chemistry-Biology Interface (Chemical informatics; Macromolecular catalysts and receptors; Enzymatic synthesis; Biosynthetic engineering; Combinatorial biosynthesis; Plant cell based chemistry; Bacterial and viral cell based chemistry; Chemistry of cellular processes in plants/animals; Receptor chemistry; Cell signaling chemistry; Drug design through understanding of disease processes; Synthetic biology; New high throughput screening techniques; Small molecular array fabrication; Chemical genomics; Chemical and biological approaches to carbohydrates proteins and nucleic acids design; Chemical and biological regulation of biosynthetic pathways; and Unnatural biomolecular analogs).

Chemical Mechanisms of Biological Systems (Mechanisms of drug design; Molecular recognition; Enzyme inhibition mechanisms; Chemical mechanisms of biological functions; Molecular machines; Chemical ecology; Metal ions in biological systems; Metalloenzymes; Chemical mechanisms, proteomics and metabonomics; Chemical imaging; Small molecule-biological target interactions; Biologically active natural products; Elucidation of biosynthetic pathways; and Simulation and modeling of biomolecules).

Current Chemical Biology

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Volume 15

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Number 4




Review Article



Research Article

The Effect of Dipeptidyl Nitrile Derivatives on Pancreatic Ductal Adenocarcinoma Cells In Vitro

, 15(4): 278 - 286

Sabrina Mendes Botelho, Fernanda dos Reis Rocho, Lorenzo Cianni, Carlos A. Montanari and Andrei Leitão*


DOI: 10.2174/2212796815666211214111243



Research Article

Detection of Oncometabolite Nicotine Imine in the Nail of Oral Cancer Patients; Predicted as an Inhibitor of DNMT1

, 15(4): 301 - 309

Anwesha Deep Dutta, Ajay Kumar, Kiran Bharat Lokhande, Manmohan Mitruka, K. Venkateswara Swamy, Jayanta K. Pal, Sachin C. Sarode and Nilesh Kumar Sharma*


DOI: 10.2174/2212796816666211223105911


Research Article

Evaluation Effects of Quercetin on Streptozotocin-treated RINm5F Pancreatic β-cells in vitro

, 15(4): 310 - 318

Maryam Mazraesefidi , Maryam Mohammad Sadeghipour , Hossein Khorramdelazad , Mahdi Mahmoodi , Alireza Khoshdel , Mohammadali Fahmidehkar , Reza Hosseiniara * and Mohammad Reza Hajizadeh*


DOI: 10.2174/2212796816666211223101206




Articles Ahead of Print







The Antibacterial Activity of Zinc Oxide Nanoparticle-Loaded Soft Contact Lens


Jactty Chew, Tommy Tong, Mun Lok Chua, Mohammad Ridwane Munngroo, Yi Xing Yap, Misni Misran and Lai Ti Gew*


DOI: 10.2174/2212796816666220419121948
View Abstract



Ethnopharmacology and Biological Activities of Aristolochia longa: A Review


Mustapha Madani, Hasna Zinelabidine*, Abderrafia Hafid, Mostfa Khouili and Latifa Bouissane*


DOI: 10.2174/2212796816666220307104606
View Abstract


QSAR Modeling of Styrylquinoline Derivatives as HIV-1 Integrase Inhibitors


Mouad Mouhsin, Samir Chtita, Mohamed Mbarki, Mustapha Oubenali*, Malika Echajia, Tarik El Ouafy and Ahmed Gamouh


DOI: 10.2174/2212796816666220318093435
View Abstract


Most Cited Articles

Review Article

Endogenous repair system of oxidative damage of DNA

, 2019; 13(2): 110-119.

Anmol Sharma, Pawan Gupta and Pranav Kumar Prabhakar*


DOI: 10.2174/2212796813666190221152908



Research Article

RNAi-mediated resistance against plant parasitic nematodes of wheat plants obtained in vitro using bioregulators of microbiological origin

, 2019; 13(1): 73-89.

Victoria A. Tsygankova *, Yaroslav V. Andrusevich, Elena N. Shysha, Lyudmila O. Biliavska, Tatyana O. Galagan, Anatoly P. Galkin, Alla I. Yemets , Galina A. Iutynska and Yaroslav B. Blume


DOI: 10.2174/2212796812666180507130017


Review Article

A recent review on drug modification using 1,2,3-triazole

, 2020; 14(2): 71-87.

Adarsh Sahu*, Preeti Sahu and Ramkishore Agrawal


DOI: 10.2174/2212796814999200807214519


Research Article

Antimicrobial activity of highly fluorinated thiocarbamates and dithiocarbamates

, 2019; 13(2): 120-128.

Amal Thebti, Ines Chniti, Med Abderrahmane Sanhoury*, Ikram Chehidi, Hadda Imene Ouzari and Abdellatif Boudabous


DOI: 10.2174/2212796812666180907153901



Research Article

Bioremediation of simulated textile effluent by an efficient bio-catalyst purified from a novel pseudomonas fluorescence lip-rl5

, 2020; 14(2): 128-139.

Ranju K. Rathour, Vaishali Sharma, Nidhi Rana, Ravi K. Bhatia and Arvind K. Bhatt*


DOI: 10.2174/2212796814666200406100247



Research Article

Cytotoxicity evaluation of dimethoxy and trimethoxy indanonic spiroisoxazolines against cancerous liver cells

, 2020; 14(1): 38-47.

Ahmad Abolhasani , Fatemeh Heidari , Somayeh Noori, Shokoufeh Mousavi and Hoda Abolhasani *


DOI: 10.2174/2212796813666190926112807


Research Article

In-vitro and in-silico characterization of xylose reductase from Emericella nidulans

, 2019; 13(2): 159-170.

Vishal Ahuja*, Aashima Sharma, Ranju Kumari Rathour, Vaishali Sharma, Nidhi Rana and Arvind Kumar Bhatt


DOI: 10.2174/2212796812666180622103906



Research Article

Anticarcinogenic effects of capsaicin-loaded nanoparticles on in vitro hepatocellular carcinoma

, 2021; 15(2): 188-201.

Noha M Hazem*, Wagdi F ElKashef, Ibrahim M El-Sherbiny, Ahmed A Emam, Dalia Shaalan and Mohamed Sobh


DOI: 10.2174/2212796814999201116211648


Research Article

Docking simulations exhibit bortezomib and other boron-con-taining peptidomimetics as potential inhibitors of sars-cov-2 main protease

, 2020; 14(4): 279-288.

Iván R Vega-Valdez, Rosalez Melvin N., Santiago-Quintana José M., Farfán-García Eunice D. and Soriano-Ursúa Marvin A.*


DOI: 10.2174/2212796814999201102195651


Review Article

Peaceful existence of tumor cells with their non-malignant neighbors: The trade of tumor cells with tumor micro-environment

, 2020; 14(4): 228-239.

Amirhosein Maali, Mohammad Sarfi, Mohammad Mirzakhani, Golnaz Goodarzi, Hosein Maghsoudi, Mahmood Maniati, Sadra Samavarchi Tehrani* and Durdi Qujeq*


DOI: 10.2174/2212796814999200925162943


Research Article

Safety evaluation of eucalyptus globulus essential oils through acute and sub-acute toxicity and skin irritation in mice and rats

, 2020; 14(3): 187-195.

Berhan Mengiste, Tizazu Zenebe*, Kassahun Dires, Ermias Lulekal, Awol Mekonnen, Nigus Zegeye and Yoseph Shiferaw


DOI: 10.2174/2212796814999200818095036



Most Accessed Articles

Serum Biomarkers for Noninvasive Diagnosis of Liver Diseases: How Laudable are These Tools?

, 2021; 15(2): 128-138.

Ankita Singh, Vipul Ranjan, Rina Das*, Karun Bhatti, Dinesh Kumar Mehta and Ram Mohan Chidurala


DOI: 10.2174/2212796814999201111204639



Cyclin-Dependent Kinase as a Novel Therapeutic Target: An Endless Story

, 2021; 15(2): 139-162.

Ahmed Mohamed Etman, Sherif Sabry Abdel Mageed, Mohamed Ahmed Ali and Mahmoud Abd El Monem El Hassab*


DOI: 10.2174/2212796814999201123194016


Anticarcinogenic Effects of Capsaicin-Loaded Nanoparticles on In vitro Hepatocellular Carcinoma

, 2021; 15(2): 188-201.

Noha M Hazem*, Wagdi F ElKashef, Ibrahim M El-Sherbiny, Ahmed A Emam, Dalia Shaalan and Mohamed Sobh


DOI: 10.2174/2212796814999201116211648





Targeting Protein Degradation in Cancer Treatment

, 2021; 15(1): 5-18.

Imane Bjij, Ismail Hdoufane, Mahmoud Soliman, Menče Najdoska-Bogdanov and Driss Cherqaoui*


DOI: 10.2174/2212796814999200609131623


Molecular Processes Involved in Pancreatic Cancer and Therapeutics

, 2021; 15(1): 85-108.

Subhajit Makar, Abhrajyoti Ghosh, Divya, Shalini Shivhare, Ashok Kumar and Sushil K. Singh*


DOI: 10.2174/2212796814999201008130819




Ovarian Cancer Biomarkers: Headway Towards Early Diagnosis

, 2021; 15(1): 109-125.

Zeba Mueed, Pankaj Kumar Rai, Seemab Siddique and Nitesh Kumar Poddar*


DOI: 10.2174/2212796815666210121095445


Hsp90 as Drug Target Against Bacterial and Fungal Infections

, 2020; 14(3): 153-168.

Mohammad W. Islam, Samir H. Bloukh, Zehra Edis* and Sabrina A. Gacem


DOI: 10.2174/2212796814666200309113100


Dose Formulation, Biodistribution and PET Imaging Studies of a First-in-Class Fluorine-18 Organophosphorus Cholinesterase Inhibitor Tracer in Rat

, 2020; 14(4): 289-303.

Kiel D. Neumann, Joseph E. Blecha, Chih-Kai Chao, Tony Huynh, Kurt R. Zinn, Henry F. VanBrocklin, Charles M. Thompson and John M. Gerdes*


DOI: 10.2174/2212796814999201005195509


Docking Simulations Exhibit Bortezomib and other Boron-containing Peptidomimetics as Potential Inhibitors of SARS-CoV-2 Main Protease

, 2020; 14(4): 279-288.

Iván R Vega-Valdez, Rosalez Melvin N., Santiago-Quintana José M., Farfán-García Eunice D. and Soriano-Ursúa Marvin A.*


DOI: 10.2174/2212796814999201102195651




Editor-in-Chief

graphic
Claudio Santi
Department of Pharmaceutical Sciences
University of Perugia
Perugia
(Italy)
Biography
View Full Editorial Board

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