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Endorsements

"All chemists and scientists will welcome Anti-Cancer Agents in Medicinal Chemistry as a fresh and vital source of information for this important field. The journal is highly recommended for essential reading."

Terrence C. Jenkins
YCR Laboratory of Drug Design, UK

Forthcoming Special Issues

Azoles in Anticancer Research: Rational Approaches, Design Strategies, Recent Insights and Future Perspectives (Part 2)


Guest Editor(s): Girish Kumar Gupta, Merve KESKİN, Sumeet Gupta
Tentative Publication Date: April, 2019
Submit Abstract via Email Download Description
Published Special Issues

Radiopharmaceuticals for Cancer Therapy and Diagnosis


Anti-Cancer Agents in Medicinal Chemistry, Volume 17, Number 3
Guest Editor(s): Ralph Santos-Oliveira

Authors' Comments
Thank you for the services I got at Bentham Science. It was a great experience publishing my paper entitled" Doxycycline As Potential Anti-cancer Agent" in the Journal "Anti-Cancer Agents In Medicinal Chemistry

Isra Ali
(Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan)


Anti-Cancer Agents in Medicinal Chemistry

,

Volume 18

-

Number 14



Biography   Open Access



Review Article



Review Article

Aberrant Sialylation in Cancer Pathology and Metastasis, a Putative Drug Target Candidate

, 18(14): 1952 - 1961

Da-Yong Lu*, Ting-Ren Lu, Bin Xu, Ajit Varki, Min Huang, Hong Zhu, Ying Shen and Nagendra S. Yarla


DOI: 10.2174/1871520618666180911113141




Review Article

Engineered Silver Nanoparticles, A New Nanoweapon Against Cancer

, 18(14): 1962 - 1969

Mohammad A. Ebrahimzadeh, Alireza Tafazoli, Javad Akhtari, Pourya Biparva and Shahram Eslami*


DOI: 10.2174/1871520618666180808093040




Review Article

Silimarin and Cancer

, 18(14): 1970 - 1974

Christina Liakopoulou, Christos Kazazis and Natalia G. Vallianou*


DOI: 10.2174/1871520618666180905154949




Review Article



Review Article

Pleiotropic Effect of Mahanine and Girinimbine Analogs: Anticancer Mechanism and its Therapeutic Versatility

, 18(14): 1983 - 1990

V. Lenin Maruthanila, Ramakrishnan Elancheran*, Ajaikumar B. Kunnumakkar, Senthamaraikannan Kabilan and Jibon Kotoky*


DOI: 10.2174/1871520618666180830151720




Review Article

Critical microRNAs in Lung Cancer: Recent Advances and Potential Applications

, 18(14): 1991 - 2005

Habib Zarredar, Khalil Ansarin, Behzad Baradaran, Najibeh Shekari, Shirin Eyvazi , Fateme Safari and Safar Farajnia*


DOI: 10.2174/1871520618666180808125459




Anti-Cancer Agents in Medicinal Chemistry, Volume 18 (2018) - Number 15


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Induction of Apoptosis by Pierisin-6 in HPV Positive HeLa and HepG2 Cancer Cells is Mediated by the Caspase-3 Dependent Mitochondrial Pathway


Subbarayan Sarathbabu, Satheesh Kumar Marimuthu, Souvik Ghatak, Subramanian Vidyalakshmi, Guruswami Gurusubramanian , Sankar Kumar Ghosh, Selvi Subramanian, Wenqing Zhang and Nachimuthu Senthil Kumar*


View Abstract View on PubMed


Synthesis of Benzo[d]imidazo[2,1-b]thiazole-Propenone Conjugates as Cytotoxic and Apoptotic Inducing Agents


Siddiq Pasha Shaik, T. Srinivasa Reddy, Satish Sunkari, A. V. Subba Rao, Korrapati Suresh Babu, Suresh K. Bhargava and Ahmed Kamal*


View Abstract View on PubMed



Design, Synthesis and Antiproliferative Evaluation of Novel 1,2,4-Triazole/Schiff Base Hybrids with Egfr and B-Raf Inhibitory Activities


Hany A. M. El-Sherief, Bahaa G. M. Youssif*, Ahmed H. Abdelazeem, Mohamed Abdel-Aziz and Hamdy M. Abdel-Rahman*


View Abstract View on PubMed


Berberine Effects on NFκB, HIF1A and NFE2L2/AP-1 Pathways in HeLa Cells


Anna Belanova , Darya Beseda , Victor Chmykhalo , Alisa Stepanova , Mariya Belousova , Vera Khrenkova , Nikolaos Gavalas and Peter Zolotukhin*


View Abstract View on PubMed


Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments


Evgenii S. Mozhaitsev, Alexandra L. Zakharenko, Evgeniy V. Suslov*, Dina V. Korchagina, Olga D. Zakharova, Inna A. Vasil’eva, Arina A. Chepanova, Ellena Black, Jinal Patel, Raina Chand, Jóhannes Reynisson, Ivanhoe K. H. Leung, Konstantin P. Volcho, Nariman F. Salakhutdinov and Olga I. Lavrik


View Abstract View on PubMed


A Novel Camptothecin Derivative 3j Inhibits Nsclc Proliferation Via Induction of Cell Cycle Arrest By Topo I-Mediated DNA Damage


Yang Liu, Jingyin Zhang, Shuyun Feng, Tingli Zhao, Zhengzheng Li, Lai Wang, Puhai Wang, Hongzhi Du*, Shengtao Yuan* and Li Sun*


View Abstract View on PubMed



Isolation of a New Sesquiterpene Lactone From Vernonia Zeylanica (L) Less and its Anti-Proliferative Effects in Breast Cancer Cell Lines


Anuka S. Mendis*, M. Ira Thabrew, Meran K. Ediriweera, Sameera R. Samarakoon, Kamani H. Tennekoon, Achyut Adhikari* and E. Dilip de Silva


View Abstract View on PubMed


Virtual Screening of Natural Products to Select Compounds with Potential Anticancer Activity


Élida Batista Vieira Sousa Cavalcanti, Mayara Barbalho FÉlix, Luciana Scotti* and Marcus Tullius Scottia


View Abstract View on PubMed


Abstracts Ahead of Print

Synthesis, Spectroscopic Properties, Crystal Structure And Biological Evaluation of New Platinum Complexes with 5-methyl-5- (2-thiomethyl)ethyl Hydantoin


Adriana Georgieva Bakalova*, Rossen Todorov Buyukliev, Rositsa Petrova Nikolova, Boris Lubomirov Shivachev, Rositsa Asenova Mihaylovac and Spiro Mihaylov Konstantinov


View Abstract


Cancer Therapy Based on Smart Drug Delivery with Advanced Nanoparticles


Xiangqi Kong, Yi Liu, Xueyan Huang, Shuai Huang, Feng Gao, Pengfei Rong, Shengwang Zhang, Kexiang Zhang and Wenbin Zeng*


View Abstract


Analysis of Comparative Proteomic and Potent Targets of Peniciketal A in Human Acute Monocytic Leukemia


Xue Gao , Yuming Zhou, Hongliu Sun, Desheng Liu , Jing Zhang , Junru Zhang, Weizhong Liu * and Xiaohong Pan*


View Abstract


Two Novel tri-aryl Derivatives Attenuate the Invasion- Promoting Effects of Stromal Mesenchymal Stem Cells on Breast Cancer


Khadijeh Moradi , Farnaz Barneh , Saeed Irian, Mohsen Amini, Raheleh Moradpoor , Amir Amanzadeh , Samira Choopani , Hamzeh Rahimi, Tayebeh Ghodselahi and Mona Salimi *


View Abstract


Synthesis and Biological Evaluation of Novel Heterocyclic Imines Linked Coumarin-Thiazole Hybrids as Anticancer Agents


Nerella Sridhar Goud , S. Mahammad Ghouse, Jatoth Vishnu, Jakkula Pranay , Ravi Alvala, Venu Talla, Insaf A. Qureshi and Mallika Alvala *


View Abstract


Biological and toxicological evaluation of N-(4methyl-phenyl)-4-methylphthalimide on bone cancer in mice.


José Roberto Santin, Gislaine Francieli da Silva, Maria Veronica Davila Pastor, Milena Fronza Broering, Roberta Nunes, Rodolpho Campos Braga, Iury Tércio Simões de Sousa, Dorimar Serafim Stiz, Kathryn Ana Bortolini Simão da Silva, Luis Carlos Stoeberl, Rogério Corrêa, Valdir Cechinel Filho, Carlos Eduardo Matos dos Santos and Nara Lins Meira Quintão*


View Abstract



GPER Overexpression in Cervical Cancer Versus Premalignant Lesions: Its Activation Induces Different forms of Cell Death.


Christian David Hernández Silva, Annie Riera Leal, Pablo César Ortiz-Lazareno, Luis Felipe Jave Suárez, Adrián Ramírez de Arellano, Edgar I. Lopez-Pulido, José G. Macías Barragan, Margarita Montoya Buelna, Judith R. Dávila Rodríguez, Paola Chabay, José Francisco Muñoz-Valle and Ana Laura Pereira-Suárez*


View Abstract


NF-κB-Induced Upregulation of miR-548as-3p Increases Invasion of NSCLC by Targeting PTEN


Sakir Akgun, Hakan Kucuksayan, Osman N. Ozes, Ozge Can, Arsenal S. Alikanoglu, Mustafa Yildiz and Hakan Akca*


View Abstract



Editor's Choice



Association of Phytol with Toxic and Cytotoxic Activities in an Antitumoral Perspective: A Meta-Analysis and Systemic Review

, 2018; 18(13): 1828 - 1837

Marcus V.O.B. Alencar, Muhammad T. Islam*, Eunus S. Ali, José V.O. Santos, Márcia F.C.J. Paz, João M.C. Sousa, Sandra M.M.M. Dantas, Siddhartha K. Mishra* and Ana A.C.M. Cavalcante


DOI: 10.2174/1871520618666180821113830



One-Pot Synthesis of Triazolo-Heterolignans: Biological Evaluation and Molecular Docking Studies as Tubulin Inhibitors

, 2018; 18(12): 1702 - 1710

Chada Raji Reddy*, Muppidi Subbarao, Jonnalagadda Vijaykumar, Surender Singh Jadav, Nilesh Sasane, Reddi Rani Valleti, Bhukya Supriya and Ramesh Ummanni*


DOI: 10.2174/1871520618666180718104647



Selection of a GPER1 Ligand via Ligand-based Virtual Screening Coupled to Molecular Dynamics Simulations and Its Anti-proliferative Effects on Breast Cancer Cells

, 2018; 18(11): 1629 - 1638

Alberto Martínez-Muñoz, Berenice Prestegui-Martel, David Méndez-Luna, Manuel J. Fragoso-Vázquez*, José Rubén García-Sánchez, Martiniano Bello, Marlet Martínez-Archundia, Alma Chávez-Blanco, Alfonso Dueñas-González, Irene Mendoza-Lujambio, José Trujillo-Ferrara and José Correa-Basurto*


DOI: 10.2174/1871520618666180510121431




68Ga-labeled HBED-CC Variant of uPAR Targeting Peptide AE105 Compared with 68Ga-NODAGA-AE105

, 2018; 18(9): 1289 - 1294

Kusum Vats, Rohit Sharma, Haladhar D. Sarma, Drishty Satpati* and Ashutosh Dash


DOI: 10.2174/1871520618666180316152618



Potential Pharmacological Inhibitors of Pim Kinase Under Clinical Trials

, 2018; 18(8): 1100 - 1114

Gomathi P. Jeyapal, Moola J.N. Chandrasekar*, Rajendiran Krishnasamy, Jubie Selvaraj, Manal Mohammad and Moola J. Nanjan


DOI: 10.2174/1871520618666180131113519



Design, Synthesis, and Biological Evaluation of New Azole Derivatives as Potent Aromatase Inhibitors with Potential Effects against Breast Cancer

, 2018; 18(7): 1016 - 1024

Fatemeh Kalalinia, Mohammad Jouya, Alireza K. Komachali, Seyed M. Aboutourabzadeh, Gholamreza Karimi*, Javad Behravan, Khalil Abnous, Leila Etemad, Hossein Kamali and Farzin Hadizadeh*


DOI: 10.2174/1871520618666180116105858




Open Access Articles

Trichinella spiralis and Tumors: Cause, Coincidence or Treatment?

, 2018; 18(8): 1091 - 1099

Chengshui Liao*, Xiangchao Cheng, Mingyuan Liu*, Xuelin Wang and Pascal Boireau




Astragalin Attenuates UVB Radiation-induced Actinic Keratosis Formation

, 2018; 18(7): 1001 - 1008

Na Li, Kun Zhang, Xin Mu, Qiong Tian, Wenli Liu, Tianyuan Gao, Xiaona Ma* and Jian Zhang*




New Strategies for Therapeutic Cancer Vaccines

, 2018; 18: 1 - 9 (E-Pub Ahead of Print)

Hanjiao Qin, Jiyao Sheng, Dan Zhang, Xuewen Zhang, Linlin Liu*, Bingjin Li*, Guangquan Li* and Zhuo Zhang





Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals

, 2016; 16(11): 1385 - 1402

Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante




Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases

, 2016; 16(7): 810 - 815

Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi




The Use of Anthracyclines for Therapy of CNS Tumors

, 2015; 15(6): 721 - 727

Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi






Episensitization: Therapeutic Tumor Resensitization by Epigenetic Agents: A Review and Reassessment

, 2014; 14(8): 1121 - 1127

Bryan Oronsky, Neil Oronsky, Susan Knox, Gary Fanger and Jan Scicinski




Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines

, 2014; 14(6): 840 - 851

Georgina A. Cardama, Maria J. Comin, Leandro Hornos, Nazareno Gonzalez, Lucas Defelipe, Adrian G. Turjanski, Daniel F. Alonso, Daniel E. Gomez and Pablo Lorenzano Menna




β2-Microglobulin-mediated Signaling as a Target for Cancer Therapy

, 2014; 14(3): 343 - 352

Takeo Nomura, Wen-Chin Huang, Haiyen E. Zhau, Sajni Josson, Hiromitsu Mimata and Leland W. K. Chung





Cytotoxicity and Apoptosis Induced by a Plumbagin Derivative in Estrogen Positive MCF-7 Breast Cancer Cells

, 2014; 14(1): 170 - 180

Sunil Sagar, Luke Esau, Basem Moosa, Niveen M. Khashab, Vladimir B. Bajic and Mandeep Kaur




Differential Effects of Polyphenols on Proliferation and Apoptosis in Human Myeloid and Lymphoid Leukemia Cell Lines

, 2013; 13(10): 1601 - 1613

Amani A Mahbub, Christine L. Le Maitre, Sarah L. Haywood-Small, Gordon J. McDougall, Neil A. Cross and Nicola Jordan-Mahy





Most Cited Articles

Cytochromes P450 and Skin Cancer: Role of Local Endocrine Pathways

, 2014; 14(1): 77-96.

Andrzej T. Slominski, Michal A. Zmijewski, Igor Semak, Blazej Zbytek, Alexander Pisarchik, Wei Li, Jordan Zjawiony and Robert C. Tuckey


DOI: 10.2174/18715206113139990308




Chemical Metabolic Inhibitors for the Treatment of Blood-Borne Cancers

, 2014; 14(2): 223-232.

Martin Villalba, Nuria Lopez-Royuela, Ewelina Krzywinska, Moeez G. Rathore, Robert A. Hipskind, Houda Haouas and Nerea Allende-Vega


DOI: 10.2174/18715206113136660374


CCL21 and IFNγ Recruit and Activate Tumor Specific T cells in 3D Scaffold Model of Breast Cancer

, 2014; 14(2): 204-210.

Vy Phan-Lai, Forrest M. Kievit, Stephen J. Florczyk, Kui Wang, Mary L. Disis and Miqin Zhang


DOI: 10.2174/18715206113136660375




Most Accessed Articles



Natural Compounds in the Chemoprevention of Malignant Melanoma

, 2018; 18(5): 631-644.

Corina Danciu*, Codruta Soica, Diana Antal, Ersilia Alexa, Ioana Z. Pavel, Roxana Ghiulai, Florina Ardelean, Roxana M. Babuta, Alexandra Popescu and Cristina A. Dehelean


DOI: 10.2174/1871520617666171121142522


Determination of the Apoptotic Effect and Molecular Docking of Benzamide Derivative XT5 in K562 Cells

, 2018; 18(11): 1521-1530.

Tulin Ozkan*, Yalda Hekmatshoar*, Tugba Ertan-Bolelli, Andry N. Hidayat, Meral Beksac, Esin Aki-Yalcin, Ismail Yalcin and Asuman Sunguroglu


DOI: 10.2174/1871520618666171229222534




Induction of HT-29 Colon Cancer Cells Apoptosis by Pyrogallol with Growth Inhibiting Efficacy Against Drug-Resistant Helicobacter pylori

, 2018; 18(13): 1875-1884.

Seemaisamy Revathi, Faruck L. Hakkim*, Neelamegam R. Kumar, Hamid A. Bakshi, Luay Rashan, Mohammed Al-Buloshi, Sidgi S.A.A. Hasson, Muthukalingan Krishnan, Farideh Javid and Kayalvizhi Nagarajan*


DOI: 10.2174/1871520618666180806104902



The Warburg Effect and the Hallmarks of Cancer

, 2017; 17(2): 164-170.

Khalid O. Alfarouk, Claudiu T. Supuran and Laurent Schwartz


DOI: 10.2174/1871520616666161031143301




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