Bentham Science Logo

Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Volume 19, 18 Issues, 2019
ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)
This journal supports open access

Ranking and Category

  • 39th of 61 in

    Chemistry, Medicinal

  • 172nd of 229 in

    Oncology

Order Your Article Before Print

Aims & Scope

Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents.

Each issue contains a series of timely in-depth/mini reviews and guest edited issues written by leaders in the field covering a range of current topics in cancer medicinal chemistry. The journal only considers high quality research papers for publication.

Anti-Cancer Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in cancer drug discovery.

Anti-Cancer Agents in Medicinal Chemistry

,

Volume 19

-

Number 7



Biography   Open Access



Review Article



Review Article



Research Article



Research Article



Research Article



Anti-Cancer Agents in Medicinal Chemistry, Volume 19 (2019) - Number 8


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


Anti-Tumor Mechanisms of Novel 3-(4-Substituted Benzyl)-5-Isopropil-5- Phenylhydantoin Derivatives in Human Colon Cancer Cell Line


Ana Obradovića, Miloš Matića, Branka Ognjanovića, Nenad Vukovićb, Milena Vukićb, Predrag Djurdjevic, Gordana Ušćumlićd, Bojan Božiće and Biljana Božić Nedeljkoviće*


DOI: 10.2174/1871520619666190425180610
View Abstract









Overcoming Cancer Cell Drug Resistance by a Folic Acid Targeted Polymeric Conjugate of Buthionine Sulfoximine


Felisa Cilurzo, Maria C. Cristiano, Marta Da Pian, Eleonora Cianflone, Luigi Quintieri*, Donatella Paolino and Gianfranco Pasut*


DOI: 10.2174/1871520619666190626114641
View Abstract View on PubMed


Abstracts Ahead of Print





Advances on the Relationship Between Endocan and Tumor


Chen Li, Hui Geng*, Linhua Ji, Xiaojing Ma, Qichao Yin and Hua Xiong


DOI: 10.2174/1871520619666190705151542
View Abstract



Iodine Bonded with Milk Protein Inhibits Benign Prostatic Hyperplasia Development in Rats


Vladimir G. Bespalov*, Valerii A. Alexandrov, Grigory V. Tochilnikov, Dmitrii Е. Lukin, Nadezhda T. Zhilinskaya, Alexandr L. Semenov, Irina N. Vasilyeva, Vladimir A. Romanov, Irina A. Tumanyan, Elena D. Ermakova, Elizaveta I. Kovalevskaya, Nadezhda V. Barakova and Denis A. Baranenko


DOI: 10.2174/1871520619666190705143927
View Abstract



Nanoliposomal Encapsulation Enhances In Vivo Anti-Tumor Activity of Niclosamide against Melanoma


Mahdi Hatamipour, Mahmoud R. Jaafari, Amir A. Momtazi-Borojeni, Mahin Ramezani and Amirhossein Sahebkar*


DOI: 10.2174/1871520619666190705120011
View Abstract



Published Contents

Editor's Choice


Synthesis and In Vitro Evaluation of Tetrahydroquinoline Derivatives as Antiproliferative Compounds of Breast Cancer via Targeting the GPER

, 2019; 19(6): 760 - 771

Oscar J. Zacarías-Lara, David Méndez-Luna, Gustavo Martínez-Ruíz, José R. García-Sanchéz, Manuel J. Fragoso-Vázquez*, Martiniano Bello, Elvia Becerra-Martínez, Juan B. García-Vázquez and José Correa-Basurto*


DOI: 10.2174/1871520618666181119094144



Design, Synthesis and Antiproliferative Evaluation of Novel 1,2,4-Triazole/Schiff Base Hybrids with EGFR and B-RAF Inhibitory Activities

, 2019; 19(5): 697 - 706

Hany A.M. El-Sherief, Bahaa G.M. Youssif*, Ahmed H. Abdelazeem, Mohamed Abdel-Aziz and Hamdy M. Abdel-Rahman*


DOI: 10.2174/1871520619666181224115346



A New Synthetic Spiroketal: Studies on Antitumor Activity on Murine Melanoma Model In Vivo and Mechanism of Action In Vitro

, 2019; 19(4): 567 - 578

Maria P. Fuggetta*, Pietro Spanu*, Fausta Ulgheri, Francesco Deligia, Paola Carta, Alberto Mannu, Veronica Trotta, Rosanna De Cicco, Adriano Barra, Enrica Zona and Franco Morelli*


DOI: 10.2174/1871520619666190131141400



Novel Benzo[B]Furans with Anti-Microtubule Activity Upregulate Expression of Apoptotic Genes and Arrest Leukemia Cells in G2/M Phase

, 2019; 19(3): 375 - 388

Karolina Królewska-Golińska, Marcin J. Cieślak*, Milena Sobczak, Rafał Dolot, Ewa Radzikowska-Cieciura, Mariola Napiórkowska, Iwona Wybrańska and Barbara Nawrot


DOI: 10.2174/1871520619666181122123552



Isolation of a New Sesquiterpene Lactone From Vernonia Zeylanica (L) Less and its Anti-Proliferative Effects in Breast Cancer Cell Lines

, 2019; 19(3): 410 - 424

Anuka S. Mendis*, Ira Thabrew, Meran K. Ediriweera, Sameera R. Samarakoon, Kamani H. Tennekoon, Achyut Adhikari* and Egodage D. de Silva


DOI: 10.2174/1871520619666181128163359




Biological Activity and Physicochemical Properties of Dipeptidyl Nitrile Derivatives Against Pancreatic Ductal Adenocarcinoma Cells

, 2019; 19(1): 112 - 120

José C. Quilles Jr, Murillo D.L. Bernardi, Pedro H.J. Batista, Samelyn C.M. Silva, Camila M.R. Rocha, Carlos A. Montanari and Andrei Leitão*


DOI: 10.2174/1871520618666181029141649



Crocetin and Crocin from Saffron in Cancer Chemotherapy and Chemoprevention

, 2019; 19(1): 38 - 47

Alessandro Colapietro, Andrea Mancini, Anna Maria D'Alessandro and Claudio Festuccia*


DOI: 10.2174/1871520619666181231112453



Biomarkers in Non-Small Cell Lung Cancer: Perspectives of Individualized Targeted Therapy

, 2018; 18(15): 2070 - 2077

Mateus N. Aoki*, Marla K. Amarante, Carlos E.C. de Oliveira and Maria A.E. Watanabe


DOI: 10.2174/1871520618666180827102101



Open Access Articles


New Strategies for Therapeutic Cancer Vaccines

, 2019; 19(2): 213 - 221

Hanjiao Qin, Jiyao Sheng, Dan Zhang, Xuewen Zhang, Linlin Liu*, Bingjin Li*, Guangquan Li* and Zhuo Zhang




Trichinella spiralis and Tumors: Cause, Coincidence or Treatment?

, 2018; 18(8): 1091 - 1099

Chengshui Liao*, Xiangchao Cheng, Mingyuan Liu*, Xuelin Wang and Pascal Boireau




Astragalin Attenuates UVB Radiation-induced Actinic Keratosis Formation

, 2018; 18(7): 1001 - 1008

Na Li, Kun Zhang, Xin Mu, Qiong Tian, Wenli Liu, Tianyuan Gao, Xiaona Ma* and Jian Zhang*





Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals

, 2016; 16(11): 1385 - 1402

Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante




Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases

, 2016; 16(7): 810 - 815

Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi




The Use of Anthracyclines for Therapy of CNS Tumors

, 2015; 15(6): 721 - 727

Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi






Episensitization: Therapeutic Tumor Resensitization by Epigenetic Agents: A Review and Reassessment

, 2014; 14(8): 1121 - 1127

Bryan Oronsky, Neil Oronsky, Susan Knox, Gary Fanger and Jan Scicinski




Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines

, 2014; 14(6): 840 - 851

Georgina A. Cardama, Maria J. Comin, Leandro Hornos, Nazareno Gonzalez, Lucas Defelipe, Adrian G. Turjanski, Daniel F. Alonso, Daniel E. Gomez and Pablo Lorenzano Menna




β2-Microglobulin-mediated Signaling as a Target for Cancer Therapy

, 2014; 14(3): 343 - 352

Takeo Nomura, Wen-Chin Huang, Haiyen E. Zhau, Sajni Josson, Hiromitsu Mimata and Leland W. K. Chung





Cytotoxicity and Apoptosis Induced by a Plumbagin Derivative in Estrogen Positive MCF-7 Breast Cancer Cells

, 2014; 14(1): 170 - 180

Sunil Sagar, Luke Esau, Basem Moosa, Niveen M. Khashab, Vladimir B. Bajic and Mandeep Kaur





Most Cited Articles

Review Article

Recent development of sulfonyl or sulfonamide hybrids as potential anticancer agents: A key review

, 2018; 18(4): 488-505.

K. P. Rakesh, Shi-Meng Wang, Jing Leng, L. Ravindar, Abdullah M. Asiri, Hadi M. Marwani and Hua-Li Qin*


DOI: 10.2174/1871520617666171103140749



Research Article

Genistein induces alterations of epigenetic modulatory signatures in human cervical cancer cells

, 2018; 18(3): 412-421.

Madhumitha Kedhari Sundaram, Mohammad Zeeshan Ansari, Abdullah Al Mutery, Maryam Ashraf, Reem Nasab, Sheethal Rai, Naushad Rais and Arif Hussain*


DOI: 10.2174/1871520617666170918142114


Research Article

Design and discovery of novel quinoxaline derivatives as dual DNA intercalators and topoisomerase II inhibitors

, 2018; 18(2): 195-209.

Ibrahim H. Eissa, Abeer M. El-Naggar*, Nour E.A. Abd El-Sattar and Ahmed S.A. Youssef


DOI: 10.2174/1871520617666170710182405



Research Article

Effects of plasma activated medium on head and neck fadu cancerous cells: Comparison of 3D and 2D response

, 2018; 18(6): 776-783.

Julie Chauvin, Florian Judee, Nofel Merbahi* and Patricia Vicendo


DOI: 10.2174/1871520617666170801111055


General Research Article

Ros-scavenging and anti-tyrosinase properties of crocetin on B16F10 murine melanoma cells

, 2018; 18(7): 1064-1069.

Seyed H. Hashemi-Shahri, Alireza Golshan, Seyed A. Mohajeri, Javad Baharara, Elaheh Amini, Farzaneh Salek, Amirhossein Sahebkar and Zahra Tayarani-Najaran*


DOI: 10.2174/1871520618666171213143455


Research Article

Structure-based design: Synthesis, X-ray crystallography, and biological evaluation of N-substituted-4-hydroxy-2-quinolone-3-carboxamides as potential cytotoxic agents

, 2018; 18(2): 263-276.

Dima A. Sabbah*, Bayan Hishmah, Kamal Sweidan, Sanaa Bardaweel, Murad AlDamen, Haizhen A. Zhong, Reema Abu Khalaf, Ameerah (Hasan Ibrahim), Tariq Al-Qirim, Ghassan Abu Sheikha and Mohammad S. Mubarak


DOI: 10.2174/1871520617666170911171152




Research Article

Apoptosis caused by triterpenes and phytosterols and antioxidant activity of an enriched flavonoid extract from passiflora mucronata

, 2018; 18(10): 1405-1416.

Isabel C.V. da Silva, Goran N. Kaluđerović, Pollyana F. de Oliveira, Denise O. Guimarães, Carla H. Quaresma, Andrea Porzel, Michelle F. Muzitano, Ludger A. Wessjohann and Ivana C.R. Leal*


DOI: 10.2174/1871520618666180315090949


General Research Article

Nanoemulsion strategy for ursolic and oleanic acids isolates from plumeria obtusa improves antioxidant and cytotoxic activity in melanoma cells

, 2018; 18(6): 847-853.

Helen L. Alvarado, Ana C. Calpena, María L. Garduño-Ramírez, Raúl Ortiz, Consolación Melguizo, José C. Prados and Beatriz Clares*


DOI: 10.2174/1871520618666180111151846




Research Article

Melatonin differentially modulates NF-кB expression in breast and liver cancer cells

, 2018; 18(12): 1688-1694.

Jucimara Colombo, Bruna V. Jardim-Perassi, João P.S. Ferreira, Cristine Z. Braga, Nathália M. Sonehara, Rubens P. Júnior, Marina G. Moschetta, Ana P. Girol and Debora A.P.C. Zuccari*


DOI: 10.2174/1871520618666180131112304



Most Accessed Articles




Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments

, 2019; 19(4): 463-472.

Evgenii S. Mozhaitsev, Alexandra L. Zakharenko, Evgeniy V. Suslov*, Dina V. Korchagina, Olga D. Zakharova, Inna A. Vasil'eva, Arina A. Chepanova, Ellena Black, Jinal Patel, Raina Chand, Jóhannes Reynisson, Ivanhoe K.H. Leung, Konstantin P. Volcho, Nariman F. Salakhutdinov and Olga I. Lavrik


DOI: 10.2174/1871520619666181207094243


BRCA1 as Target for Breast Cancer Prevention and Therapy

, 2015; 15(1): 4-14.

Alberto P.G. Romagnolo, Donato F. Romagnolo and Ornella I. Selmin


DOI: 10.2174/1871520614666141020153543


Biomarkers in Non-Small Cell Lung Cancer: Perspectives of Individualized Targeted Therapy

, 2018; 18(15): 2070-2077.

Mateus N. Aoki*, Marla K. Amarante, Carlos E.C. de Oliveira and Maria A.E. Watanabe


DOI: 10.2174/1871520618666180827102101


Cancer Nanotechnology-An Excursion on Drug Delivery Systems

, 2018; 18(15): 2078-2092.

Mala Sharma, Chitranshu Pandey, Neha Sharma, Mohammad A. Kamal, Usman Sayeed and Salman Akhtar*


DOI: 10.2174/1871520618666180720164015


Synthesis of Asymmetric 1-Thiocarbamoyl Pyrazoles as Potent Anti- Colon Cancer, Antioxidant and Anti-Inflammatory Agent

, 2018; 18(15): 2117-2123.

Dattatraya G. Raut, Sandeep B. Patil, Vikas D. Kadu, Mahesh G. Hublikar and Raghunath B. Bhosale*


DOI: 10.2174/1871520618666181112122528


Sorafenib as a Salvage Therapy in FLT3-ITD Negative Relapse/ Refractory Acute Myeloid Leukemia

, 2018; 18(10): 1489-1494.

Nan Yang, Zhenyang Gu, Zhanxiang Liu, Wenrong Huang, Shuhong Wang, Lili Wang and Chunji Gao*


DOI: 10.2174/1871520618666180307125544





Editor-in-Chief

Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
ICCF-CNRS UMR 6296
Université Clermont Auvergne
Clermont-Ferrand
France

Biography View Full Editorial Board

Journal History

Current Medicinal Chemistry - Anti-Cancer Agents was launched in 2001 and later renamed in 2006 as Anti-Cancer Agents in Medicinal Chemistry.

Related Journals

Related eBooks

eBooks Catalog