ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)


Volume 13, 8 Issues, 2017


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Medicinal Chemistry

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Dimitra Hadjipavlou-Litina


Aristotle University of Thessaloniki
Thessaloniki
Greece


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"Medicinal Chemistry is an invaluable journal, which contains the latest outstanding developments in medicinal chemistry. It is recommended to all scientists working in this field."

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University of Sydney, Australia

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Medicinal Chemistry

,

Volume 13

-

Number 8



Review Article

The Role of QSAR and Virtual Screening Studies in Type 2 Diabetes Drug Discovery

, 13(8): 706 - 720

Simone Q. Pantaleao, Drielli G.V. Fujii, Vinicius G. Maltarollo, Danielle da C. Silva, Gustavo H.G. Trossini, Karen C. Weber, Luis P.B. Scott and Kathia M. Honorio*


DOI: 10.2174/1573406413666170522152102


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Research Article

Isolation of Chlorogenic Acid from Soil Borne Fungi Screlotium rolfsii, their Reversal of Multidrug Resistance and Anti-proliferative in Mouse Lymphoma Cells

, 13(8): 721 - 726

Bashir Ahmad, Muhammad Rizwan, Abdur Rauf *, Muslim Raza, Shumaila Bashir , Joseph Molnar, Akos Csonka, Diana Szabo, Mohammad S. Mubarak, Mah Noor and Bina S. Siddiqui


DOI: 10.2174/1573406413666170612110443


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Research Article

IRS-1 pY612 and Akt-1/PKB pT308 Phosphorylation and Antiinflammatory Effect of Diindolylmethane in Adipocytes Cocultured with Macrophages

, 13(8): 727 - 733

Alfonso Lopez-Vazquez, Jesus J. Garcia-Banuelos*, Angelica S. Gonzalez-Garibay, Pedro E. Urzua-Lozano, Susana Del Toro-Arreola, Miriam R. Bueno-Topete, Sergio Sanchez-Enriquez, Jose F. Munoz-Valle, Luis F. Jave-Suarez, Juan Armendariz-Borunda and Blanca E. Bastidas-Ramirez*


DOI: 10.2174/1573406413666170922095011


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Research Article

Design, Synthesis, and Biological Evaluation of C-2 Substituted 3Hthieno[ 2,3-d]pyrimidin-4-one Derivatives as Novel FGFR1 Inhibitors

, 13(8): 753 - 760

Ping Guo, Zixin Xie, Huan Zhang, Zaikui Zhang , Chao Han , Donghua Cheng, Dan Lin, Yuan Zhang, Xuebao Wang, Xin Guo and Faqing Ye *


DOI: 10.2174/1573406413666170623084525


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Research Article

Synthesis and Biological Evaluation of Curcumin-Nitroxide-Based Molecular Hybrids as Antioxidant and Anti-Proliferative Agents

, 13(8): 761 - 772

Balazs Bognar, M. Lakshmi Kuppusamy, Esha Madan, Tamas Kalai, Maria Balog, Jozsef Jeko, Periannan Kuppusamy and Kalman Hideg*


DOI: 10.2174/1871520617666170522124712


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The Quantum Chemical and QSAR Studies on Acinetobacter Baumannii Oxphos Inhibitors


Hakan Sezgin Sayiner*, Afaf A.S. Abdalrahm, Murat A. Başaran, Vasyl Kovalishyn and Fatma Kandemirli*


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Day/Night and Summer/Winter Changes in Serum Total Antioxidant Capacity


Armando L. Morera-Fumero*, Pedro Abreu-Gonzalez, Manuel Henry-Benitez, Lourdes Fernandez-Lopez, Estefania Diaz-Mesa, Maria del Rosario Cejas-Mendez and Fernando Guillen-Pino


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14-Formyl-15-aryloxy/methoxymatrine and 14-Aryloxymethylidenylmatrine Derivatives as Anti-HIV-1 Agents


Jiulin Huang, Si-Ying Xiang, Min Lv, Liu-Meng Yang, Yuanyuan Zhang, Yong-Tang Zheng and Hui Xu*


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USP7: Target Validation and Drug Discovery for Cancer Therapy


Jin Zhou*, Jinzheng Wang, Chao Chen, Haoliang Yuan, Xiaoan Wen and Hongbin Sun


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Investigation on the Effects of Antimicrobial imidazo[2,1-b]thiazole Derivatives on the Genitourinary Microflora


Rita Morigi, Beatrice Vitali, Cecilia Prata, Rogers A.Ñ. Palomino, Alessandra Graziadio, Alessandra Locatelli, Mirella Rambaldi and Alberto Leoni*


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Synthesis, Antiproliferative and Pro-Apoptotic Effects of Nitrostyrenes and Related Compounds in Burkitt’s Lymphoma


Andrew J. Byrne, Sandra A. Bright, Darren Fayne, James P. McKeown, Thomas McCabe, Brendan Twamley, Clive Williams and Mary J. Meegan*


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New Perspectives of Alzheimer Disease Diagnosis – the Most Popular and Future Methods


Katarzyna Pietrzak, Kamila Czarnecka, Elżbieta M ikiciuk-Olasik and Paweł Szymański*


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A novel method to synthesize phosphocreatine and phosphocreatine prodrugs


Maria Arkel, Patrizia Garbati, Annalisa Salis, Gianluca Damonte, Nara Liessi, Enrico Adriano, Umberto Benatti, Maurizio Balestrino and Enrico Millo*


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Antibacterial Assessment of Heteroaryl, Vinyl, Benzyl, and Alkyl Tetrazole Compounds


Joshua Dudley, Liana Feinn, Heather DeFrancesco, Erica Lindsay, Adiel Coca* and Elizabeth Lewis Roberts


View Abstract



Inhibition of Adipogenesis by Thiourea Derivatives


Hina Siddiqui*, Sarah Shafi, Farah Mukhtar, Asma Ejaz, Atta-ur-Rahman and M. Iqbal Choudhary*


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Anthranilic Acid Derivatives: Novel Inhibitors of Protein Glycation and the Associated Oxidative Stress in the Hepatocytes


Humera Jahan*, Muhammad Iqbal Choudhary, Amber Atta, Khalid Mohammad Khan and Atta-ur- Rahman


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Synthesis, structure and antiproliferative activity of new pyrazolo[4,3-e]triazolo[4,5-b][1,2,4]triazine derivatives


Mariusz Mojzych*, Pawel Tarasiuk, Zbigniew Karczmarzyk, Malgorzata Juszczak, Wojciech Rzeski, Andrzej Fruziński and Artur Wozny


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9-(4'-dimethylaminophenyl)-2,6,7-trihydroxy-xanthene-3-one is a potentially novel antiplatelet drug which antagonizes the effect of thromboxane A2


Lenka Applova, Elma Veljovic, Samija Muratovic, Jana Karlickova, Katerina Macakova, Davorka Završnik, Luciano Saso, Kemal Duric and Premysl Mladenka*


View Abstract



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