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Current Chemical Biology

Volume 15, 4 Issues, 2021
ISSN: 1872-3136 (Online)
ISSN: 2212-7968 (Print)
This journal supports open access

Aims & Scope

Current Chemical Biology aims to publish full-length and mini reviews as well as research papers on exciting new developments at the chemistry-biology interface, covering topics relating to Chemical Synthesis, Science at Chemistry-Biology Interface and Chemical Mechanisms of Biological Systems.

Current Chemical Biology covers the following areas: Chemical Synthesis (Syntheses of biologically important macromolecules including proteins, polypeptides, oligonucleotides, oligosaccharides etc.; Asymmetric synthesis; Combinatorial synthesis; Diversity-oriented synthesis; Template-directed synthesis; Biomimetic synthesis; Solid phase biomolecular synthesis; Synthesis of small biomolecules: amino acids, peptides, lipids, carbohydrates and nucleosides; and Natural product synthesis).

Science at Chemistry-Biology Interface (Chemical informatics; Macromolecular catalysts and receptors; Enzymatic synthesis; Biosynthetic engineering; Combinatorial biosynthesis; Plant cell based chemistry; Bacterial and viral cell based chemistry; Chemistry of cellular processes in plants/animals; Receptor chemistry; Cell signaling chemistry; Drug design through understanding of disease processes; Synthetic biology; New high throughput screening techniques; Small molecular array fabrication; Chemical genomics; Chemical and biological approaches to carbohydrates proteins and nucleic acids design; Chemical and biological regulation of biosynthetic pathways; and Unnatural biomolecular analogs).

Chemical Mechanisms of Biological Systems (Mechanisms of drug design; Molecular recognition; Enzyme inhibition mechanisms; Chemical mechanisms of biological functions; Molecular machines; Chemical ecology; Metal ions in biological systems; Metalloenzymes; Chemical mechanisms, proteomics and metabonomics; Chemical imaging; Small molecule-biological target interactions; Biologically active natural products; Elucidation of biosynthetic pathways; and Simulation and modeling of biomolecules).

Current Chemical Biology

,

Volume 14

-

Number 4



Biography   Open Access



Review Article

Peaceful Existence of Tumor Cells with Their Non-malignant Neighbors: The Trade of Tumor Cells with Tumor Microenvironment

, 14(4): 228 - 239

Amirhosein Maali, Mohammad Sarfi, Mohammad Mirzakhani, Golnaz Goodarzi, Hosein Maghsoudi, Mahmood Maniati, Sadra Samavarchi Tehrani* and Durdi Qujeq*


DOI: 10.2174/2212796814999200925162943


Research Article

DFT Study and Synthesis of Novel Bioactive Bispyrazole using Mg/Al-LDH as a Solid Base Catalyst

, 14(4): 240 - 249

Soufiane Akhramez, Youness Achour, Mustapha Dib, Lahoucine Bahsis*, Hajiba Ouchetto, Abderrafia Hafid, Mostafa Khouili* and Mohammadine El Haddad


DOI: 10.2174/2212796814999200918175018




Research Article



Research Article   Open Access



Research Article

Dose Formulation, Biodistribution and PET Imaging Studies of a First-in-Class Fluorine-18 Organophosphorus Cholinesterase Inhibitor Tracer in Rat

, 14(4): 289 - 303

Kiel D. Neumann, Joseph E. Blecha, Chih-Kai Chao, Tony Huynh, Kurt R. Zinn, Henry F. VanBrocklin, Charles M. Thompson and John M. Gerdes*


DOI: 10.2174/2212796814999201005195509




Current Chemical Biology, Volume 15 (2021) - Number 1


This issue is in progress but contains articles that are final and fully citable.

Abstracts Ahead of Print

Published Contents

Open Access Articles

Docking Simulations Exhibit Bortezomib and other Boron-containing Peptidomimetics as Potential Inhibitors of SARS-CoV-2 Main Protease

, 2020; 14(4): 279 - 288

Iván R Vega-Valdez, Rosalez Melvin N., Santiago-Quintana José M., Farfán-García Eunice D. and Soriano-Ursúa Marvin A.*




Hsp90 as Drug Target Against Bacterial and Fungal Infections

, 2020; 14(3): 153 - 168

Mohammad W. Islam, Samir H. Bloukh, Zehra Edis* and Sabrina A. Gacem




POCl3 Mediated Syntheses, Pharmacological Evaluation and Molecular Docking Studies of Some Novel Benzofused Thiazole Derivatives as a Potential Antioxidant and Anti-inflammatory Agents

, 2020; 14(1): 58 - 68

Dattatraya G. Raut*, Sandeep B. Patil, Prafulla B. Choudhari, Vikas D. Kadu, Anjana S. Lawand, Mahesh G. Hublikar and Raghunath B. Bhosale





Cytotoxicity Evaluation of Dimethoxy and Trimethoxy Indanonic Spiroisoxazolines Against Cancerous Liver Cells

, 2020; 14(1): 38 - 47

Ahmad Abolhasani , Fatemeh Heidari , Somayeh Noori, Shokoufeh Mousavi and Hoda Abolhasani *










Functional Characterization of Chitin and Chitosan

, 2009; 3(2): 203 - 230

Inmaculada Aranaz, Marian Mengibar, Ruth Harris, Ines Panos, Beatriz Miralles, Niuris Acosta, Gemma Galed and Angeles Heras




Cause of Chirality Consensus

, 2008; 2(2): 153 - 158

Salla Jaakkola, Vivek Sharma and Arto Annila






Most Cited Articles

Research Article

Bioremediation of simulated textile effluent by an efficient bio-catalyst purified from a novel pseudomonas fluorescence lip-rl5

, 2020; 14(2): 128-139.

Ranju K. Rathour, Vaishali Sharma, Nidhi Rana, Ravi K. Bhatia and Arvind K. Bhatt*


DOI: 10.2174/2212796814666200406100247



Research Article

Cytotoxicity evaluation of dimethoxy and trimethoxy indanonic spiroisoxazolines against cancerous liver cells

, 2020; 14(1): 38-47.

Ahmad Abolhasani , Fatemeh Heidari , Somayeh Noori, Shokoufeh Mousavi and Hoda Abolhasani *


DOI: 10.2174/2212796813666190926112807


Research Article

Nigella sativa seed protects against cadmium-induced renal toxicity in rats

, 2020; 14(2): 140-149.

Ikenna Kingsley Uchendu* and Henshaw Uchechi Okoroiwu


DOI: 10.2174/2212796814666200520083818



Research Article

Dose formulation, biodistribution and pet imaging studies of a first-in-class fluorine-18 organophosphorus cholinesterase inhibitor tracer in rat

, 2020; 14(4): 289-303.

Kiel D. Neumann, Joseph E. Blecha, Chih-Kai Chao, Tony Huynh, Kurt R. Zinn, Henry F. VanBrocklin, Charles M. Thompson and John M. Gerdes*


DOI: 10.2174/2212796814999201005195509


Research Article

Docking simulations exhibit bortezomib and other boron-con-taining peptidomimetics as potential inhibitors of sars-cov-2 main protease

, 2020; 14(4): 279-288.

Iván R Vega-Valdez, Rosalez Melvin N., Santiago-Quintana José M., Farfán-García Eunice D. and Soriano-Ursúa Marvin A.*


DOI: 10.2174/2212796814999201102195651


Research Article

Differential metabolites markers from trunking and stressed non-trunking sago palm (Metroxylon sagu rottb.)

, 2020; 14(4): 262-278.

Hasnain Hussain*, Wei-Jie Yan, Zainab Ngaini, Norzainizul Julaihi, Rina Tommy and Showkat Ahmad Bhawani


DOI: 10.2174/2212796814999200930120925


Research Article

Dft study and synthesis of novel bioactive bispyrazole using mg/al-ldh as a solid base catalyst

, 2020; 14(4): 240-249.

Soufiane Akhramez, Youness Achour, Mustapha Dib, Lahoucine Bahsis*, Hajiba Ouchetto, Abderrafia Hafid, Mostafa Khouili* and Mohammadine El Haddad


DOI: 10.2174/2212796814999200918175018


Review Article

Peaceful existence of tumor cells with their non-malignant neighbors: The trade of tumor cells with tumor micro-environment

, 2020; 14(4): 228-239.

Amirhosein Maali, Mohammad Sarfi, Mohammad Mirzakhani, Golnaz Goodarzi, Hosein Maghsoudi, Mahmood Maniati, Sadra Samavarchi Tehrani* and Durdi Qujeq*


DOI: 10.2174/2212796814999200925162943


Research Article

Comparative study on polyphenols content and antioxidant activity of three sweet peppers varieties (Capsicum annuum l.)

, 2020; 14(4): 250-261.

Hadia Hemmami, Bachir Ben Seghir*, Abdelkrim Rebiai, Abdelhamid Khelef and Zeghoud Soumeia


DOI: 10.2174/2212796814999200907162105


Review Article (Mini-Review)

Hsp90 as drug target against bacterial and fungal infections

, 2020; 14(3): 153-168.

Mohammad W. Islam, Samir H. Bloukh, Zehra Edis* and Sabrina A. Gacem


DOI: 10.2174/2212796814666200309113100


Biography

Meet our co-editor

, 2020; 14(3): 151-152.

Michio Iwaoka


DOI: 10.2174/221279681403201228092856


Research Article

Evaluation of snake venom’s phospholipasea2 enzyme inhibition activity of cyphostemma adenocoule

, 2020; 14(3): 196-202.

Atul Kaushik*, Teamrat S. Tesfai, Daniel K. Barkh, Furtuna K. Ghebremeskel, Habtom G. Zerihun and Saron W. Woldeab


DOI: 10.2174/2212796814999200917114914


Research Article

Iron-sulfur-nitrosyl complex increases the resistance of pea seedling to water deficiency

, 2020; 14(3): 203-215.

Irina Zhigacheva*, Vladimir Binyukov, Elena Mil, Natalya Krikunova, Inna Generozova and Maksud Rasulov


DOI: 10.2174/2212796814999200907162619



Most Accessed Articles

Peaceful Existence of Tumor Cells with Their Non-malignant Neighbors: The Trade of Tumor Cells with Tumor Microenvironment

, 2020; 14(4): 228-239.

Amirhosein Maali, Mohammad Sarfi, Mohammad Mirzakhani, Golnaz Goodarzi, Hosein Maghsoudi, Mahmood Maniati, Sadra Samavarchi Tehrani* and Durdi Qujeq*


DOI: 10.2174/2212796814999200925162943


Docking Simulations Exhibit Bortezomib and other Boron-containing Peptidomimetics as Potential Inhibitors of SARS-CoV-2 Main Protease

, 2020; 14(4): 279-288.

Iván R Vega-Valdez, Rosalez Melvin N., Santiago-Quintana José M., Farfán-García Eunice D. and Soriano-Ursúa Marvin A.*


DOI: 10.2174/2212796814999201102195651



Differential Metabolites Markers from Trunking and Stressed Non-Trunking Sago Palm (Metroxylon sagu Rottb.)

, 2020; 14(4): 262-278.

Hasnain Hussain*, Wei-Jie Yan, Zainab Ngaini, Norzainizul Julaihi, Rina Tommy and Showkat Ahmad Bhawani


DOI: 10.2174/2212796814999200930120925


DFT Study and Synthesis of Novel Bioactive Bispyrazole using Mg/Al-LDH as a Solid Base Catalyst

, 2020; 14(4): 240-249.

Soufiane Akhramez, Youness Achour, Mustapha Dib, Lahoucine Bahsis*, Hajiba Ouchetto, Abderrafia Hafid, Mostafa Khouili* and Mohammadine El Haddad


DOI: 10.2174/2212796814999200918175018


Molecular Processes Involved in Pancreatic Cancer and Therapeutics

, 2021; 15(1): 85-108.

Subhajit Makar, Abhrajyoti Ghosh, Divya, Shalini Shivhare, Ashok Kumar and Sushil K. Singh*


DOI: 10.2174/2212796814999201008130819





Dose Formulation, Biodistribution and PET Imaging Studies of a First-in-Class Fluorine-18 Organophosphorus Cholinesterase Inhibitor Tracer in Rat

, 2020; 14(4): 289-303.

Kiel D. Neumann, Joseph E. Blecha, Chih-Kai Chao, Tony Huynh, Kurt R. Zinn, Henry F. VanBrocklin, Charles M. Thompson and John M. Gerdes*


DOI: 10.2174/2212796814999201005195509


Hsp90 as Drug Target Against Bacterial and Fungal Infections

, 2020; 14(3): 153-168.

Mohammad W. Islam, Samir H. Bloukh, Zehra Edis* and Sabrina A. Gacem


DOI: 10.2174/2212796814666200309113100



Safety Evaluation of Eucalyptus globulus Essential Oils through Acute and Sub-acute Toxicity and Skin Irritation in Mice and Rats

, 2020; 14(3): 187-195.

Berhan Mengiste, Tizazu Zenebe*, Kassahun Dires, Ermias Lulekal, Awol Mekonnen, Nigus Zegeye and Yoseph Shiferaw


DOI: 10.2174/2212796814999200818095036


Iron-Sulfur-Nitrosyl Complex Increases the Resistance of Pea Seedling to Water Deficiency

, 2020; 14(3): 203-215.

Irina Zhigacheva*, Vladimir Binyukov, Elena Mil, Natalya Krikunova, Inna Generozova and Maksud Rasulov


DOI: 10.2174/2212796814999200907162619





Editor-in-Chief

graphic
Claudio Santi
Department of Pharmaceutical Sciences
University of Perugia
Perugia
(Italy)
Biography
View Full Editorial Board

Journal History

Current Chemical Biology was launched in 2007. Dr. Claudio Santi serves as the Editor-in-Chief of the journal.

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