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Current Alzheimer Research

Volume 19, 14 Issues, 2022
ISSN: 1875-5828 (Online)
ISSN: 1567-2050 (Print)
This journal supports open access

Aims & Scope

Current Alzheimer Research publishes peer-reviewed frontier review, research, drug clinical trial studies and letter articles on all areas of Alzheimer’s disease. This multidisciplinary journal will help in understanding the neurobiology, genetics, pathogenesis, and treatment strategies of Alzheimer’s disease. The journal publishes objective reviews written by experts and leaders actively engaged in research using cellular, molecular, and animal models. The journal also covers original articles on recent research in fast emerging areas of molecular diagnostics, brain imaging, drug development and discovery, and clinical aspects of Alzheimer’s disease. Manuscripts are encouraged that relate to the synergistic mechanism of Alzheimer's disease with other dementia and neurodegenerative disorders. Book reviews, meeting reports and letters-to-the-editor are also published. The journal is essential reading for researchers, educators and physicians with interest in age-related dementia and Alzheimer’s disease. Current Alzheimer Research provides a comprehensive 'bird's-eye view' of the current state of Alzheimer's research for neuroscientists, clinicians, health science planners, granting, caregivers and families of this devastating disease.

Current Alzheimer Research

,

Volume 19

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Number 3




Systematic Review Article

Effects of Supplementation with Probiotics in Experimental Models of Alzheimer's Disease: A Systematic Review of Animal Experiments

, 19(3): 188 - 201

Francisca Idalina Neta, Francisco Emílio Simplício de Souza, André Lima Batista, Francisco Irochima Pinheiro, Ricardo Ney Cobucci and Fausto Pierdoná Guzen*


DOI: 10.2174/1567205019666220318092003



Research Article

Oculomotor Abnormalities during Reading in the Offspring of Late-Onset Alzheimer's Disease

, 19(3): 212 - 222

Gerardo Fernández*, Ana Paula González, Carolina Abulafia, Leticia Fiorentini, Osvaldo Agamennoni and Salvador M. Guinjoan


DOI: 10.2174/1567205019666220413075840



Research Article

Polymorphism Rs2421943 of the Insulin-Degrading Enzyme Gene and the Risk of Late-Onset Alzheimer's Disease

, 19(3): 236 - 245

Omar Šerý*, Tomáš Zeman, Alice Hálová, Vladimír Janout, Jana Janoutová, Jan Lochman and Vladimir J. Balcar


DOI: 10.2174/1567205019666220302120950


Research Article

Co-Treatment with the Herbal Medicine SIP3 and Donepezil Improves Memory and Depression in the Mouse Model of Alzheimer's Disease

, 19(3): 246 - 263

Quan Feng Liu, Hoon Choi, Taekwon Son, Young-Mi Kim, Suganya Kanmani, Young-Won Chin, Seung-Nam Kim, Kwang Ki Kim, Kyu-Won Kim and Byung-Soo Koo*


DOI: 10.2174/1567205019666220413082130


Current Alzheimer Research, Volume 19 (2022) - Number 4


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


Gastrointestinal Changes and Alzheimer's Disease


Mona Sohrabi, Bijayani Sahu, Harpreet Kaur, Wendie Hasler, Atish Prakash and Colin K. Combs


DOI: 10.2174/1567205019666220617121255
View Abstract View on PubMed


Primary Sjögren’s Syndrome Presenting With Rapidly Progressive Dementia: A Case Report


Konstantinos Notas, Vasileios Papaliagkas*, Martha Spilioti, Ioannis Papagiannis, Petros Nemtsas, Athanasios Poulopoulos, Konstantinos Kouskouras, Ioannis Diakogiannis and Vasilios K. Kimiskidis*


DOI: 10.2174/1567205019666220627094707
View Abstract View on PubMed



Temporal Speech Parameters Detect Mild Cognitive Impairment in Different Languages: Validation and Comparison of the Speech-GAP Test® in English and Hungarian


János Kálmán*, Davangere P. Devanand, Gábor Gosztolya, Réka Balogh, Nóra Imre, László Tóth, Ildikó Hoffmann, Ildikó Kovács, Veronika Vincze and Magdolna Pákáski


DOI: 10.2174/1567205019666220418155130
View Abstract View on PubMed



Abstracts Ahead of Print

Novel PSEN1 (P284S) Mutation Causes Alzheimer's Disease with Cerebellar Amyloid β-protein deposition


Mingrong Xia, Chenhao Gao, Huayuan Wang, Junkui Shang, Ruijie Liu, Yang You, Weizhou Zang and Jiewen Zhang*


DOI: 10.2174/1567205019666220718151357
View Abstract



Effect of simultaneous dual-task training on regional cerebral blood flow in older adults with amnestic mild cognitive impairment


Yota Kunieda*, Chiaki Arakawa, Takumi Yamada, Shingo Koyama, Mizue Suzuki, Daisuke Ishiyama, Minoru Yamada, Ryuto Hirokawa, Tadamitsu Matsuda, Shintaro Nio, Tomohide Adachi, Haruhiko Hoshino and Toshiyuki Fujiwara


DOI: 10.2174/1567205019666220627091246
View Abstract


Vascular lesions and brain atrophy in Alzheimer’s, vascular and mixed dementia: an optimized 3T MRI protocol reveals distinctive radiological profiles


Cotta Ramusino Matteo*, Vitali Paolo, Anzalone Nicoletta, Melazzini Luca, Lombardo Francesca Paola, Farina Lisa Maria, Bernini Sara and Costa Alfredo


DOI: 10.2174/1567205019666220620112831
View Abstract


Ameliorative effects of phytomedicines on Alzheimer’s patients


Rekha Khandia*, Neerja Viswanathan, Shailja Singhal, Taha Alqahtani, Mohannad A. Almikhlafi, Alexander Nikolaevich Simonov and Ghulam Md. Ashraf


DOI: 10.2174/1567205019666220610155608
View Abstract


Blood Biomarkers Predict Future Cognitive Decline after Military-Related Traumatic Brain Injury


Sara. M. Lippa*, Jessica Gill, Tracey A. Brickell, Vivian A. Guedes, Louis M. French and Rael T. Lange


DOI: 10.2174/1567205019666220330144432
View Abstract


Published Contents

Editor's Choice



Unfolded p53 as a Marker of Oxidative Stress in Mild Cognitive Impairment, Alzheimer’s and Parkinson’s Disease

, 2021; 18(9): 695 - 700

Sara García*, Olaya Amor-Gutiérrez, María Palomares-Albarrán, Celia Toyos-Rodríguez, Fernando Cuetos, Carmen Martínez, Agustín Costa-García, Maria Teresa Fernández-Sánchez, Alfredo de la Escosura-Muñiz and Antonello Novelli


DOI: 10.2174/1567205018666211117101216



Palmitoylated Prolactin-releasing Peptide Reduced Aβ Plaques and Microgliosis in the Cerebellum: APP/PS1 Mice Study

, 2021; 18(8): 607 - 622

Anna Mengr, Lucie Hrubá, Aneta Exnerová, Martina Holubová, Andrea Popelová, Blanka Železná, Jaroslav Kuneš and Lenka Maletínská*


DOI: 10.2174/1567205018666210922110652



A Novel Probiotic Formula, BIOCG, Protects Against Alzheimer’s-Related Cognitive Deficits via Regulation of Dendritic Spine Dynamics

, 2021; 18(7): 558 - 572

Miao Sun*, Wenchenyang Bao, Chengyu Huang, Ziyue Xia, Changliang Zhang, Guangxian Wang, Runxin Wang, Jiangyu Li, Shaun Roux, Qian Li, Dongmei Zou, Kai Ma* and Xiaofeng Bao*


DOI: 10.2174/1567205018666211022091110




The Janus-like Association between Proton Pump Inhibitors and Dementia

, 2021; 18(6): 453 - 469

Anna Papazoglou, Muhammad I. Arshaad, Christina Henseler, Johanna Daubner, Karl Broich, Britta Haenisch and Marco Weiergräber*


DOI: 10.2174/1567205018666210929144740




Accelerated Epigenetic Aging in Peripheral Blood does not Predict Dementia Risk

, 2021; 18(5): 443 - 451

P.D. Fransquet, P. Lacaze, R. Saffery, R.C. Shah, R. Vryer, A. Murray, R.L. Woods and J. Ryan*


DOI: 10.2174/1567205018666210823100721



High Fat Diet Aggravates AD-Related Pathogenic Processes in APP/PS1 Mice

, 2021; 18(4): 310 - 325

Xiaokang Gong, Zheng Liang, Wei Liu, Yang Zhao, Youhua Yang, Mengjuan Wu, Jinting Shang, Yifan Xiao, Yong Mei, Qiqi Su, Binlian Sun, Jian Bao* and Xiji Shu*


DOI: 10.2174/1567205018666210628100812



Open Access Articles


Random-Forest-Algorithm-Based Applications of the Basic Characteristics and Serum and Imaging Biomarkers to Diagnose Mild Cognitive Impairment

, 2022; 19(1): 76 - 83

Juan Yang, Haijing Sui, Ronghong Jiao, Min Zhang, Xiaohui Zhao, Lingling Wang, Wenping Deng and Xueyuan Liu*




Inflammation in the CNS: Understanding Various Aspects of the Pathogenesis of Alzheimer's Disease

, 2022; 19(1): 16 - 31

Julia Doroszkiewicz*, Piotr Mroczko and Agnieszka Kulczyńska-Przybik*





Mitochondrially-Targeted Therapeutic Strategies for Alzheimer’s Disease

, 2021; 18(10): 753 - 771

Isaac G. Onyango*, James P. Bennett and Gorazd B. Stokin




Heterogeneity of Tau Deposition and Microvascular Involvement in MCI and AD

, 2021; 18(9): 711 - 720

Annie G. Bryant, Mary K. Manhard, David H. Salat, Bruce R. Rosen, Bradley T. Hyman, Keith A. Johnson, Susie Huang, Rachel E. Bennett and Yi-Fen Yen*




Microglia and its Genetics in Alzheimer's Disease

, 2021; 18(9): 676 - 688

Xinyan Liang , Haijian Wu, Mark Colt , Xinying Guo, Brock Pluimer , Jianxiong Zeng, Shupeng Dong and Zhen Zhao*






The Janus-like Association between Proton Pump Inhibitors and Dementia

, 2021; 18(6): 453 - 469

Anna Papazoglou, Muhammad I. Arshaad, Christina Henseler, Johanna Daubner, Karl Broich, Britta Haenisch and Marco Weiergräber*





Pregabalin Treatment does not Affect Amyloid Pathology in 5XFAD Mice

, 2021; 18(4): 283 - 297

Katherine R. Sadleir*, Jelena Popovoic, Wei Zhu, Cory T. Reidel, Ha Do, Richard B. Silverman and Robert Vassar




Real-world Utilisation of the Rivastigmine Transdermal Patches Accompanying the Use of Risk Minimisation Tools in Patients with Dementia

, 2021; 18(4): 273 - 282

Fritjof Reinhardt, Nikolaos Scarmeas, Rajesh Karan, Uday K. Veldandi, Sunil Modali*, Krishna Duvvuri and Rashid K. Pathan




Clinical Phenotype and Mutation Spectrum of Alzheimer’s Disease with Causative Genetic Mutation in a Chinese Cohort

, 2021; 18(3): 265 - 272

Chenhui Mao, Jie Li, Liling Dong, Xinying Huang, Dan Lei, Jie Wang, Shanshan Chu, Caiyan Liu, Bin Peng, Gustavo C. Román, Liying Cui and Jing Gao*






Most Cited Articles






Review Article

Mitigating Alzheimer’s disease with natural polyphenols: A review

, 2019; 16(6): 529-543.

Roger Gaudreault* and Normand Mousseau*


DOI: 10.2174/1567205016666190315093520


Review Article

Learning from the past: A review of clinical trials targeting amyloid, tau and neuroinflammation in Alzheimer’s disease

, 2020; 17(2): 112-125.

Kelly Ceyzériat, Thomas Zilli, Philippe Millet, Giovanni B. Frisoni, Valentina Garibotto and Benjamin B. Tournier*


DOI: 10.2174/1567205017666200304085513


Research Article

Resveratrol rescues tau-induced cognitive deficits and neuropathology in a mouse model of tauopathy

, 2019; 16(8): 710-722.

Xiao-Ying Sun, Quan-Xiu Dong, Jie Zhu, Xun Sun, Li-Fan Zhang, Mandy Qiu, Xiao-Lin Yu* and Rui-Tian Liu*


DOI: 10.2174/1567205016666190801153751


Review Article

Neuroinflammation in alzheimer’s disease: Microglia, molecular participants and therapeutic choices

, 2019; 16(7): 659-674.

Haijun Wang, Yin Shen, Haoyu Chuang, Chengdi Chiu, Youfan Ye and Lei Zhao*


DOI: 10.2174/1567205016666190503151648



Systemic Review Article

Midlife modifiable risk factors for dementia: A systematic review and meta-analysis of 34 prospective cohort studies

, 2019; 16(14): 1254-1268.

Xiao-Ying Li , Min Zhang*, Wei Xu, Jie-Qiong Li, Xi-Peng Cao , Jin-Tai Yu * and Lan Tan*


DOI: 10.2174/1567205017666200103111253


Research Article

The temporal relationship between pain intensity and pain interference and incident dementia

, 2019; 16(2): 109-115.

Ali Ezzati*, Cuiling Wang, Mindy J. Katz, Carol A. Derby, Andrea R. Zammit, Molly E. Zimmerman, Jelena M. Pavlovic, Martin J. Sliwinski and Richard B. Lipton


DOI: 10.2174/1567205016666181212162424


Systematic Review Article

Physical activity as a moderator of alzheimer pathology: A systematic review of observational studies

, 2019; 16(4): 362-378.

Kristian Steen Frederiksen*, Le Gjerum, Gunhild Waldemar and Steen Gregers Hasselbalch


DOI: 10.2174/1567205016666190315095151


Research Article

A pilot study of exenatide actions in alzheimer’s disease

, 2019; 16(8): 741-752.

Roger J. Mullins, Maja Mustapic, Chee W. Chia, Olga Carlson, Seema Gulyani, Joyce Tran, Yazhou Li, Mark P. Mattson, Susan Resnick, Josephine M. Egan, Nigel H. Greig and Dimitrios Kapogiannis*


DOI: 10.2174/1567205016666190913155950


Review Article

Pharmacological interventions to attenuate Alzheimer’s disease progression: The story so far

, 2019; 16(3): 261-277.

Firas H. Bazzari*, Dalaal M. Abdallah and Hanan S. El-Abhar


DOI: 10.2174/1567205016666190301111120



Most Accessed Articles

Learning from the Past: A Review of Clinical Trials Targeting Amyloid, Tau and Neuroinflammation in Alzheimer’s Disease

, 2020; 17(2): 112-125.

Ceyzériat, Kelly; Zilli, Thomas; Millet, Philippe; Frisoni, Giovanni B.; Garibotto, Valentina; Tournier, Benjamin B.


DOI: 10.2174/1567205017666200304085513


Depression in Dementia or Dementia in Depression? Systematic Review of Studies and Hypotheses

, 2020; 17(1): 16-28.

Brzezińska, Agnieszka; Bourke, Julius; Rivera-Hernández, Rayito; Tsolaki, Magda; Woźniak, Joanna; Kaźmierski, Jakub


DOI: 10.2174/1567205017666200217104114



Genetic Variants and Oxidative Stress in Alzheimer’s Disease

, 2020; 17(3): 208-223.

Kowalska, Marta; Wize, Katarzyna; Prendecki, Michał; Lianeri, Margarita; Kozubski, Wojciech; Dorszewska, Jolanta


DOI: 10.2174/1567205017666200224121447


Mechanisms of Anticholinesterase Interference with Tau Aggregation Inhibitor Activity in a Tau-Transgenic Mouse Model

, 2020; 17(3): 285-296.

Riedel, Gernot; Klein, Jochen; Niewiadomska, Grazyna; Kondak, Constantin; Schwab, Karima; Lauer, Dilyara; Magbagbeolu, Mandy; Steczkowska, Marta; Zadrozny, Maciej; Wydrych, Malgorzata; Cranston, Anna; Melis, Valeria; Santos, Renato X.; Theuring, Franz; Harrington, Charles R.; Wischik, Claude M.


DOI: 10.2174/1567205017666200224120926




Alterations in Mitochondrial Dynamic-related Genes in the Peripheral Blood of Alzheimer’s Disease Patients

, 2020; 17(7): 616-625.

Pakpian, Nattaporn; Phopin, Kamonrat; Kitidee, Kuntida; Govitrapong, Piyarat; Wongchitrat, Prapimpun


DOI: 10.2174/1567205017666201006162538


Association Between Anemia and Dementia: A Nationwide, Population-based Cohort Study in Taiwan

, 2020; 17(2): 196-204.

Hong, Chien-Tai; Hsieh, Yi-Chen; Liu, Hung-Yi; Chiou, Hung-Yi; Chien, Li-Nien


DOI: 10.2174/1567205017666200317101516


Exploring Shared Pathogenesis of Alzheimer’s Disease and Type 2 Diabetes Mellitus via Co-expression Networks Analysis

, 2020; 17(6): 566-575.

Zhu, Yukun; Ding, Xuelu; She, Zhaoyuan; Bai, Xue; Nie, Ziyang; Wang, Feng; Wang, Fei; Geng, Xin


DOI: 10.2174/1567205017666200810164932



Intracranial Atherosclerotic Stenosis is Related to Post-stroke Cognitive Impairment: A Cross-sectional Study of Minor Stroke

, 2020; 17(2): 177-184.

Gong, Li; Wang, Haichao; Dong, Qiong; Zhu, Xiaoping; Zheng, Xiaoran; Gu, Yongzhe; Cai, Wangli; Zhao, Yanxin; Liu, Xueyuan


DOI: 10.2174/1567205017666200303141920



Automatic Detection of Cognitive Impairments through Acoustic Analysis of Speech

, 2020; 17(1): 60-68.

Nagumo, Ryosuke; Zhang, Yaming; Ogawa, Yuki; Hosokawa, Mitsuharu; Abe, Kengo; Ukeda, Takaaki; Sumi, Sadayuki; Kurita, Satoshi; Nakakubo, Sho; Lee, Sangyoon; Doi, Takehiko; Shimada, Hiroyuki


DOI: 10.2174/1567205017666200213094513


Microglia in Alzheimer’s Disease

, 2020; 17(1): 29-43.

Süß, Patrick; Schlachetzki, Johannes C.M.


DOI: 10.2174/1567205017666200212155234




Editor-in-Chief

graphic
Debomoy K. Lahiri
(19340 citations)
Department of Psychiatry
Indiana University School of Medicine
Indianapolis, IN
(United States)
Biography
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