Spinal Surgery Biomechanics: Principles for Residents and Students provides a comprehensive overview of the biomechanical principles essential for understanding spinal surgery techniques. This book explores key topics, including pedicle screw anchorage, lumbar total disc replacement, interbody fusion techniques, and spinal surgery in osteoporotic patients. It also covers degenerative spondylolisthesis, interspinous devices, and spinal stability classification systems. Written for students, residents, and researchers, this volume simplifies complex biomechanical concepts with clear explanations, clinical insights, and up-to-date research findings. Key Features: - Covers essential biomechanics relevant to spinal surgery procedures. - Discusses surgical approaches, implant selection, and stability mechanisms. - Examines spine surgery in osteoporotic and degenerative conditions. - Explores motion-preserving and fusion-based spinal implants. - Reviews classification systems for spinal trauma and instability.

Promising Cancer Therapeutic Drug Targets: Recent Advancements offers a comprehensive overview of novel and emerging strategies in cancer therapy. The book explores cutting-edge approaches such as exosomal delivery systems, CRISPR/Cas9 gene editing, and immunotoxins, alongside targeting mechanisms like cancer stem cells, apoptosis pathways, and key signaling processes. A strong emphasis is placed on the therapeutic potential of natural compounds in disrupting cancer progression and enhancing treatment response. Chapters are organized around molecular targets, therapeutic pathways, and bioactive agents to provide a clear, thematic structure. Key Features - In-depth exploration of CRISPR/Cas9, exosomes, and stem cell-targeted therapy - Focus on natural compounds in cancer treatment - Insights into key signaling pathways (Hippo, Hedgehog, STAT3) - Discussion on apoptosis and drug resistance mechanisms.

Gut Microbiota and their Impact on Disease Pathways and Interventions discusses the intricate world of gut microbiota and its profound influence on human health and disease. This comprehensive volume explores the microbiome's pivotal role in conditions ranging from obesity and cardiovascular disease to inflammatory bowel disease, diabetes, ocular diseases, and neurological disorders. It offers cutting-edge insights into therapeutic strategies such as probiotics, prebiotics, and fecal microbiota transplantation, alongside emerging approaches like gut microbial metabolites as diagnostic biomarkers. It serves as a vital resource for understanding and harnessing the role of gut health in disease prevention and management. Key Features: - Multidisciplinary approach integrating microbiology, medicine, and biotechnology. - Innovative treatment modalities including personalized medicine based on microbiome analysis. - Exploration of gut-brain, gut-heart, and gut-immune system interactions.

Organ-specific Parasites in Cattle explores parasitic diseases affecting various organs in cattle, offering a deep dive into their diagnosis, treatment, and prevention. The book provides valuable insights into the etiology, symptoms, and pathophysiology of parasitic infections across critical organ systems, including the gastrointestinal tract, urogenital system, circulatory system, and more. With an emphasis on the latest research, it highlights advanced diagnostics, histopathological techniques, and the development of antiparasitic drugs and vaccines. Readers will gain a thorough understanding of host-parasite interactions, resistance mechanisms, and effective control strategies, all presented with detailed explanations and visual aids. Designed to serve as a key reference, this book is essential for students, researchers, veterinary practitioners, and academicians aiming to deepen their knowledge in parasitology and animal health. Key Features: - Comprehensive coverage of organ-specific parasitic diseases in cattle - Detailed focus on diagnosis, treatment, and preventive strategies - Latest advancements in anti-parasitic drugs and vaccines

Infections and Male Infertility (Part I): General Pathophysiology, Diagnosis, and Treatment explores the complex link between infections and male infertility, providing a comprehensive examination of their impact on reproductive health. This book integrates key concepts from molecular biology, immunology, and clinical practice to highlight the pathophysiology, diagnosis, and treatment of infection-induced infertility. Key Features: - Multidisciplinary insights from molecular biology, immunology, and reproductive medicine. - Comprehensive coverage of infections affecting male fertility, including diagnosis and treatment. - Discussion of emerging therapies, including stem cell research and personalized medicine.

Advancements in Cancer Research: Exploring Diagnostics and Therapeutic Breakthroughs is a comprehensive resource that highlights the latest innovations in cancer research. This book bridges the gap between cutting-edge science and clinical applications, offering insights into the molecular mechanisms, diagnostic advancements, and novel therapeutic strategies revolutionizing cancer care. Organized into thematic sections, the book explores critical areas such as molecular biomarkers, immunotherapy, nanotechnology in diagnostics and treatment, and targeted therapies. Topics include the role of TP53 mutations in colorectal cancer, nanocarriers for melanoma therapy, RNA-based therapeutics for colon cancer, and biomaterials for bone tumor management. Readers will also discover how emerging technologies like nanotheranostics and transethosomes are paving the way for personalized cancer care. Key Features: - Insights into molecular and nanotechnology-driven cancer therapies. - Exploration of diagnostics and biomarker applications. - Multidisciplinary approaches to advancing patient care. - Analysis of current trends and prospects in oncology.

Common Ear Diseases in Dogs: Diagnosis and Management is an essential resource for veterinarians, veterinary students, and researchers focusing on ear health in dogs. This comprehensive guide covers the anatomy, physiology, microbiology, and pathology of canine ears, offering a thorough understanding of ear structure and function. It covers diagnosing, treating, and managing various ear conditions, including otitis externa, otitis media, aural hematomas, traumatic injuries, and more. Chapters explore cutting-edge diagnostic techniques, surgical interventions like ear canal ablation, and pain management strategies, making it a valuable tool for clinical practice. Written by subject matter experts, the book bridges foundational knowledge with advanced clinical applications, helping readers develop expertise in ear disease management. Key Features: - Provides an in-depth understanding of ear anatomy, physiology, and pathology in dogs. - Covers diagnosis, treatment, and management of common ear conditions, including infections, injuries, and neurological issues. - Features practical guides on advanced procedures like laser surgery and ear canal ablation.

The book focuses on a new interdisciplinary understanding of the metabolic syndrome (MetS) for better health maintenance. It provides an updated understanding of the underlying principles, possible targets, implementation approaches and the effectiveness of various avoidance strategies in MetS. The chapters cover a wide range of topics, including major advances in general aspects of metabolic syndrome, functional changes, new diagnostic methods, genotype-phenotype associations, the effect of exercise and multitarget pharmacotherapeutic strategies for MetS and perspectives on personalized medicine. It also discusses epigenetic mechanisms underlying MetS-related processes and epigenetic strategies to prevent related diseases. The book also presents summarized information about the associated factors and mechanisms linking cancer and MetS and to identify potential targets for the treatment of these patients. A better understanding of the various linkages will provide greater insight into the management of cancer patients by preventing MetS and related alterations. Key Features - Comprehensive information focused on the biological factors and physiological changes associated with metabolic syndrome - Updates on metabolic syndrome diagnosis and management - Summarized information on clinical implications for cancer therapy - Thoroughly referenced chapters with summaries and discussions for quick understanding The book is an informative resource for interdisciplinary scientists and researchers in life sciences and medicine. Furthermore, it, including the insulin-like growth factor (IGF-1) pathway, estrogen signaling, visceral adiposity, hyperinsulinemia, hyperglycemia, aromatase activity, adipokinase production, angiogenesis, oxidative stress, DNA damage and pro-inflammatory cytokines, and their clinical implications in cancer therapy.

This book provides a comprehensive exploration of vector-borne diseases, highlighting current trends, control strategies, and their public health implications. With contributions from experts, it informs readers about specific diseases caused by vectors such as mosquitoes and other zoonotic agents, presenting innovative approaches for prevention and management. The book begins with a focus on mosquito control strategies, emphasizing their significance in reducing the burden of vector-borne diseases. It further unravels the impact of Rickettsial infections, providing insights into these often-underdiagnosed diseases. Scrub typhus is explored through its co-infections with other vector-borne zoonotic diseases and analyzed using an integrated omics approach to better understand its pathogenesis and treatment. The final chapter sheds light on lymphatic filariasis, a neglected tropical disease, covering its endemic nature, clinical manifestations like elephantiasis and hydrocele, mass drug administration programs, and novel vector management techniques. This resource is ideal for public health professionals, researchers, and students, providing actionable insights into combating vector-borne diseases globally. Key Features: Discusses innovative mosquito control strategies and integrated vector management. Explores lesser-known diseases like scrub typhus and Rickettsial infections with advanced omics approaches. Provides a detailed analysis of lymphatic filariasis, including treatment strategies like antifilarial drugs and mass drug administration. Highlights the importance of public health interventions in combating neglected tropical diseases.

Parasitic Diseases of Goats provides a comprehensive exploration of parasitic infections affecting goats and their impact on various organ systems. The book covers a wide range of parasitic diseases, including those affecting the gastrointestinal, respiratory, cardiovascular, nervous, and urogenital systems, as well as the liver, pancreas, skin, and musculoskeletal system. Diagnostic techniques and therapeutic approaches for managing these infections are also discussed in the chapters of this book. This book is an essential resource for veterinarians, researchers, students, and professionals in parasitology and veterinary medicine. Key features include detailed descriptions of parasite-related diseases, their pathogenesis, diagnostic methods, and treatment strategies to improve goat health and management.