Brain Tumor Drug Development provides a clear, multidisciplinary update on modern therapies for glioblastoma and other aggressive brain tumors. The book focuses on improving drug precision, crossing the blood-brain barrier, identifying biomarkers, designing effective trials, and accelerating translation from research to real patient care. Key Features Discusses how to overcome the blood-brain barrier using advanced delivery methods Explains how to improve drug penetration and specificity with nano and polymer-based systems Explores new therapies through immunotherapy, gene therapy, and personalised medicine Outlines preclinical models and identifies biomarkers to support clinical success Details regulatory-aligned clinical trial strategies for faster translation

The Role of Asymmetric Synthesis in Drug Discovery presents a comprehensive overview of how enantioselective synthesis drives the development of safer, more effective therapeutics. Because the 3D arrangement of atoms profoundly affects a drug's activity, efficacy, and safety, asymmetric synthesis enables the precise production of single enantiomers-minimizing side effects and maximizing therapeutic performance. In the era of precision medicine, this selective control is indispensable for designing molecules that interact optimally with biological targets. Spanning ten chapters, the book highlights cutting-edge experimental research on the asymmetric synthesis of diverse bioactive heterocycles. Topics include foundational principles of enantioselective synthesis, chiral heterocycles, alkaloids, terpenoids, spirooxindoles, dihydropyrimidinones, piperazine derivatives, and asymmetric oxazines. Additional chapters explore chiral triazoles, benzimidazoles, and broader classes of chiral pharmaceuticals synthesized through asymmetric strategies. Together, these chapters illustrate both the scientific depth and therapeutic potential of modern asymmetric methodologies. The book serves as a forward-looking resource designed to inspire new research on chiral heterocycles and to support ongoing efforts in medicinal chemistry and drug design. Key Features: Explores core principles of enantioselective and asymmetric synthesis in drug discovery. Highlights synthetic strategies for diverse bioactive chiral heterocycles and natural products. Showcases experimental advancements in the synthesis of alkaloids, terpenoids, spirooxindoles, and more. Examines green, modern, and emerging approaches to asymmetric synthesis. Demonstrates therapeutic relevance through biological evaluations and pharmaceutical applications. Inspires future research on novel chiral scaffolds for drug development.

AI-Powered Innovations in Ophthalmic Diagnosis and Treatment is a forward-looking assessment of how artificial intelligence is redefining modern eye care. The book connects computational advancements with clinical practice, presenting a structured, multidisciplinary roadmap for integrating AI across diagnostic workflows, therapeutic decisions, patient monitoring, and future-ready developments in ophthalmology. Across seven insightful chapters, the book establishes AI-driven frameworks that enhance ophthalmic workflows through federated, reinforcement, and prompt-based learning. Subsequent chapters detail AI-enabled diagnostics for retinal, glaucoma, and ocular surface diseases, alongside governance challenges in real-world deployment. The book also explores personalized therapeutics by integrating AI with Traditional Chinese Medicine, stem cell strategies, and precision care models. It further examines next-generation technologies including LLMs, AIGC, and multi-agent systems and their transformative roles in clinical research, drug discovery, and medical education. Broader applications are highlighted through AI's connection to systemic disease surveillance and wearable healthcare. The final chapters address regulatory, ethical, and legal considerations, concluding with a visionary outlook on quantum computing and global collaboration shaping the future of ophthalmic AI. Uniting clinical evidence, computational methodologies, and patient-centred perspectives, this book provides actionable insights for implementing responsible, explainable, and scalable AI within ophthalmic practice. Key Features Introduces AI-driven frameworks enhancing diagnostic and clinical workflows in ophthalmology. Presents practical AI applications for retinal, glaucoma, and ocular surface disease detection. Explores AI-guided personalized therapeutics, including TCM integration and stem cell innovations. Examines emerging technologies such as LLMs, AIGC, and multi-agent systems in research and education. Addresses ethical, regulatory, and governance challenges in deploying medical AI. Highlights AI’s role in systemic disease prediction, wearable monitoring, and next-generation healthcare models. Envisions future innovations shaped by quantum computing and global AI collaboration.

A clear and timely overview of how global climate shifts are reshaping the spread, intensity, and impact of major vector-borne diseases.The Changing Trends of Vector-Borne Diseases to Climate Change explains how rising temperatures, changing rainfall patterns, humidity levels, and global movement accelerate mosquito and tick proliferation, expand endemic zones, and increase disease severity. Focusing on dengue and Crimean-Congo Hemorrhagic Fever (CCHF), it also highlights clinical features, transmission pathways, prevention strategies, and the urgent need for surveillance and preparedness. Key Features: - Explains how climate variables drive the spread of vector-borne diseases. - Highlights major case studies, including dengue and CCHF. - Describes transmission pathways, clinical progression, and public-health risks. - Emphasizes prevention, surveillance, and global health preparedness.

Brain Tumour Drug Development provides a clear, multidisciplinary update on modern therapies for glioblastoma and other aggressive brain tumours. The book focuses on improving drug precision, crossing the blood-brain barrier, identifying biomarkers, designing effective trials, and accelerating translation from research to real patient care. Key Features Overcomes the blood-brain barrier using advanced delivery methods Improves drug penetration & specificity with nano and polymer-based systems Explores new therapies through immunotherapy, gene therapy, and personalised medicine Builds preclinical models & identifies biomarkers to support clinical success Designs regulatory-aligned clinical trial strategies for faster translation

Current and Emerging Concepts of Polycystic Ovary Syndrome – Manual from M.P. PCOS Society is a comprehensive and authoritative guide that explores the multifaceted nature of PCOS, redefining the understanding, diagnosis, and management of Polycystic Ovary Syndrome (PCOS). Drawing upon cross-disciplinary insights and multi-institutional expertise, this two-part series unravels its epidemiology, diagnostic complexities, and phenotypic diversity. It dives deep into hormonal, metabolic, genetic, and environmental dimensions to present an integrated view of the syndrome. It presents PCOS not as a single disorder, but as an evolving clinical spectrum. It serves as both a foundation for clinicians and a catalyst for future research, setting the stage for Volume II, which expands into advanced management and innovative therapeutic paradigms. Key Features Examines the global epidemiology, pathophysiology, and heterogeneity of PCOS. Clarifies diagnostic criteria and phenotypic variations through evidence-based insights. Explores hormonal, metabolic, genetic, and environmental mechanisms driving PCOS. Integrates emerging concepts from microbiome science, endocrinology, and mental health. Highlights the evolving clinical understanding shaped by interdisciplinary collaboration.

Current and Emerging Concepts of Polycystic Ovary Syndrome – Manual from M.P. PCOS Society is a comprehensive and authoritative guide that explores the multifaceted nature of PCOS, redefining the understanding, diagnosis, and management of Polycystic Ovary Syndrome (PCOS). Drawing upon cross-disciplinary insights and multi-institutional expertise, this two part series unravels its epidemiology, diagnostic complexities, and phenotypic diversity. It dives deep into hormonal, metabolic, genetic, and environmental dimensions to present an integrated view of the syndrome. It presents PCOS not as a single disorder, but as an evolving clinical spectrum. It serves as both a foundation for clinicians and a catalyst for future research, setting the stage for Volume II, which expands into advanced management and innovative therapeutic paradigms. Key Features Examines the global epidemiology, pathophysiology, and heterogeneity of PCOS. Clarifies diagnostic criteria and phenotypic variations through evidence-based insights. Explores hormonal, metabolic, genetic, and environmental mechanisms driving PCOS. Integrates emerging concepts from microbiome science, endocrinology, and mental health. Highlights the evolving clinical understanding shaped by interdisciplinary collaboration.

Handbook of Practical Pharmacology – I serves as a vital bridge between theoretical pharmacology and laboratory application, equipping learners with the experimental skills essential to understanding drug actions through hands-on animal studies. A comprehensive, curriculum-based guide designed for second-year B. Pharm. students, fully aligned with the Pharmacy Council of India’s 2014 regulations. The book introduces students to fundamental laboratory concepts, animal handling as per CCSEA guidelines, drug administration routes, and experimental models like Rotarod, Actophotometer, and rabbit eye studies. It explores pharmacodynamic responses to various classes of drugs, including hepatic enzyme inducers, skeletal muscle relaxants, anticonvulsants, and anxiolytics. Each chapter combines clarity, precision, and ethical awareness, ensuring reproducibility and adherence to professional standards. Serving both as a laboratory manual and a learning companion, this handbook enhances analytical thinking and experimental competence, helping students gain a deeper, practice-based understanding of pharmacology. Key Features · Aligns with the PCI 2014 syllabus for second-year B. Pharm. students. · Explains fundamental experimental pharmacology concepts and instrumentation. · Demonstrates animal handling and drug administration techniques per CCSEA guidelines. · Guides pharmacodynamic testing using established models like Rotarod, Actophotometer, and MES. · Promotes laboratory competence, ethical compliance, and analytical reasoning in pharmacology

Drug Repurposing for Antivirals is a timely volume bridging pharmacology, virology, and computational science to present a cohesive understanding of the scientific and translational potential of drug repurposing in antiviral therapy with innovative strategies of finding new antiviral applications for existing drugs, an approach that shortens development timelines, reduces costs, and accelerates clinical deployment The book covers core concepts, from historical successes to modern applications in combating viral diseases. It explores computational screening, molecular docking, and AI-driven tools for identifying candidate molecules; experimental validation methods; and real-world case studies involving influenza, SARS-CoV-2, HIV, and hepatitis viruses. Special focus is given to host-targeted antivirals, broad-spectrum agents, and strategies to counter viral resistance. Regulatory aspects, challenges, and future directions for integrating repurposed antivirals into clinical practice are also discussed. Key Features: Integrates theory, methodology, and real-world case studies. Covers both computational and experimental approaches. Highlights implications for pandemic preparedness and rapid-response drug discovery. Includes contributions from leading experts in virology, medicinal chemistry, and pharmacology.

Impact of Incomplete Metabolism on Health uncovers how the buildup of toxic intermediates, enzyme deficiencies, and pathway impairments destabilize metabolic homeostasis. These disruptions contribute to chronic diseases, oxidative stress, mitochondrial dysfunction, and a wide range of cellular abnormalities. The book begins with the fundamental principles of metabolism and then systematically explains the biochemical origins of incomplete reactions and their physiological consequences. Subsequent chapters explore metabolic syndrome, inborn errors of metabolism, and other clinically significant disorders arising from flawed metabolic pathways. The later sections delve into diagnostic strategies, therapeutic innovations, and emerging fields such as nutrigenomics, enzyme replacement therapy, and personalized metabolic medicine. Supported by contemporary research, detailed pathway illustrations, and case-based clinical insights, this book serves as both an academic foundation and a practical guide for understanding the biochemical roots of human disease. Key Features Clarifies the biochemical basis and clinical implications of incomplete metabolic processes. Illustrates metabolic pathways through detailed, accurate, and easy-to-understand diagrams. Connects theoretical concepts to real-world practice using case studies and clinical correlations. Integrates updated research across biochemistry, molecular biology, and clinical medicine. Explores diagnostic tools, therapeutic approaches, and emerging personalized interventions.