ISSN (Print):
0929-8673
ISSN (Online):
1875-533X
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Current Medicinal Chemistry

All Open Access articles of this journal are also available on ScienceDirect.

Impact Factor: 3.5

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Volume 33 , Issues 46, 2026

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Volume 33, Issue 8 , 2026


Editorial

Using Disease Models for Mechanistic Studies: Special Focus on Gene Editing

Pp: 1497-1502
Author(s): Vasily Nikolaevich Sukhorukov and Alexander Nikolaevich Orekhov*
DOI: 10.2174/0109298673450033251020095814
Published on: 24 October, 2025

Review Article

3D Bioprinting and Microfluidic-based Devices for Cancer Detection and Drug Treatment: Focus on Prostate Cancer

Pp: 1503-1522
Author(s): Jay Sibbitts, Lucia Di Pietro, Anna Privitera, Vincenzo Cardaci, Salvatore Maugeri, Massimo Camarda* and Giuseppe Caruso*
DOI: 10.2174/0109298673298382240307040239
Published on: 08 March, 2024

Research Article open_access

Mouse Model of Low-density Lipoprotein Desialylation In Vivo

Pp: 1523-1537
Author(s): Dmitry Kashirskikh*, Nelya Chicherina, Victor Glanz, Alexander Orekhov and Igor Sobenin
DOI: 10.2174/0109298673294745240528092506
Published on: 31 May, 2024

Research Article

Relationship between Cellular Oxygen Consumption and Atherosclerosis-associated Mitochondrial Mutations (Variants of the Mitochondrial Genome)

Pp: 1538-1550
Author(s): Alexander Nikolaevich Orekhov*, Vasily Vladimirovich Sinyov, Mikhail Yurievich Vyssokikh, Ludmila Manukhova, Maria Vladimirovna Marey, Plamena Rumyanova Angelova, Andrey Vladimirovich Omelchenko, Andrey Yurievich Vinokurov, Zukhra B. Khasanova and Igor Aleksandrovich Sobenin
DOI: 10.2174/0109298673302002240605092523
Published on: 14 June, 2024

Research Article

Diuretic and Anti-hyperuricemic Effects of Geranyl Acetate in Rats

Pp: 1551-1567
Author(s): Sarmad Nawaz Shah, Waqas Younis*, Arquimedes Gasparotto Junior*, Wajiha Manzoor, Muhammad Nasir Hayat Malik, Muhammad Naveed Mushtaq, Muhammad Usman Munir, Asifa Bashir, Shabana Bibi, Muhammad Talha and Francislaine Aparecida dos Reis Livero
DOI: 10.2174/0109298673300632240823061848
Published on: 04 September, 2024

Research Article open_access

Mitochondrial Dysfunction Associated with mtDNA Mutation: Mitochondrial Genome Editing in Atherosclerosis Research

Pp: 1568-1582
Author(s): Victoria A. Khotina*, Andrey Y. Vinokurov, Vasily V. Sinyov, Alexander D. Zhuravlev, Daniil Y. Popov, Vasily N. Sukhorukov, Igor A. Sobenin and Alexander N. Orekhov
DOI: 10.2174/0109298673323639240926095549
Published on: 11 October, 2024

Research Article

Mechanisms of Inflammation Chronification: Gene and Epigenetic Regulation of Intolerant Response (Trained Immunity)

Pp: 1583-1598
Author(s): Alexander Nikolaevich Orekhov*, Andrey Vladimirovich Omelchenko, Alexander Dmitrievich Zhuravlev, Andrey Yurievich Vinokurov, Natalia Vladimirovna Elizova, Vasily Vladimirovich Sinyov, Igor Alexandrovich Sobenin and Vasily Nikolaevich Sukhorukov
DOI: 10.2174/0109298673431092250819054506
Published on: 29 August, 2025

Commentary

Cells with Defective Mitophagy Do Not Accumulate Atherogenic LDL-Derived Cholesterol

Pp: 1599-1604
Author(s): Evgeny E. Borisov*, Volha I. Summerhill, Victoria A. Khotina, Anna M. Kosyreva, Tatiana I. Kovyanova, Vasily N. Sukhorukov and Alexander N. Orekhov*
DOI: 10.2174/0109298673294632250108102414
Published on: 27 February, 2025

General Review Article open_access

Binding Specificity and Local Frustration in Structure-based Drug Discovery

Pp: 1605-1615
Author(s): Zhiqiang Yan*, Yuqing Li, Ying Cao, Xuetao Tao, Jin Wang* and Yongsheng Jiang*
DOI: 10.2174/0109298673376099250428054846
Published on: 12 May, 2025

General Review Article

Medical Artificial Intelligence: Opportunities and Challenges In Infectious Disease Management

Pp: 1616-1634
Author(s): Ankit Sahoo, Janhvi Singh, Kainat Alam, Nabil K. Alruwaili, Alhussain Aodah, Waleed H. Almalki, Salem Salman Almujri, Majed Alrobaian, Md Abul Barkat, Tanuja Singh, Jonathan A. Lal and Mahfoozur Rahman*
DOI: 10.2174/0109298673390868250728103906
Published on: 19 August, 2025

General Research Article

Expression of TCEAL2 is a Novel Prognostic Biomarker and Potential Therapeutic Target in Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma

Pp: 1635-1650
Author(s): Jinyuan Li, Zhen Ye, Yuhong Gan, Dongbing Li* and Yibiao Chen*
DOI: 10.2174/0109298673371499250714133701
Published on: 26 August, 2025

General Research Article

DDX59-AS1: A Novel Prognostic Biomarker and Immunotherapy Predictor in Lung Adenocarcinoma

Pp: 1651-1664
Author(s): Yanli Wang, Wei Li, Su Wei, Lixi Zhang, Dongbing Li and Xu Qi*
DOI: 10.2174/0109298673359149250212073143
Published on: 18 February, 2025

General Research Article

LncRNA HYMAI Promotes Endothelial Cell Autophagy via miR-19a-3p/ ATG14 to Attenuate the Progression of Coronary Atherosclerotic Disease

Pp: 1665-1684
Author(s): Shao Ouyang, Zhi-Xiang Zhou, Hui-Ting Liu, Kun Zhou, Zhong Ren, Huan Liu, Qian Xu, Zhaoyue Wang, Wenhao Xiong, Gaofeng Zeng and Zhi-Sheng Jiang*
DOI: 10.2174/0109298673428431250917095939
Published on: 02 October, 2025

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