Current Medicinal Chemistry

Volume 33, Issue 8

Editorial

Using Disease Models for Mechanistic Studies: Special Focus on Gene Editing

Pp: 1497-1502
Author(s): Vasily Nikolaevich Sukhorukov and Alexander Nikolaevich Orekhov*
DOI: 10.2174/0109298673450033251020095814

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Review Article

3D Bioprinting and Microfluidic-based Devices for Cancer Detection and Drug Treatment: Focus on Prostate Cancer

Pp: 1503-1522
Author(s): Jay Sibbits, Lucia Di Pietro, Anna Privitera, Vincenzo Cardaci, Salvatore Maugeri, Massimo Camarda* and Giuseppe Caruso*
DOI: 10.2174/0109298673298382240307040239

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Research Article

Mouse Model of Low-density Lipoprotein Desialylation In Vivo

Pp: 1523-1537
Author(s): Dmitry Kashirskikh*, Nelya Chicherina, Victor Glanz, Alexander Orekhov and Igor Sobenin
DOI: 10.2174/0109298673294745240528092506

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Research Article

Relationship between Cellular Oxygen Consumption and Atherosclerosis-associated Mitochondrial Mutations (Variants of the Mitochondrial Genome)

Pp: 1538-1550
Author(s): Alexander Nikolaevich Orekhov*, Vasily Vladimirovich Sinyov, Mikhail Yurievich Vyssokikh, Ludmila Manukhova, Maria Vladimirovna Marey, Plamena Rumyanova Angelova, Andrey Vladimirovich Omelchenko, Andrey Yurievich Vinokurov, Zukhra B. Khasanova and Igor Aleksandrovich Sobenin
DOI: 10.2174/0109298673302002240605092523

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Research Article

Diuretic and Anti-hyperuricemic Effects of Geranyl Acetate in Rats

Pp: 1551-1567
Author(s): Sarmad Nawaz Shah, Waqas Younis, Arquimedes Gasparotto Junior*, Wajiha Manzoor, Muhammad Nasir Hayat Malik, Muhammad Naveed Mushtaq, Muhammad Usman Munir, Asifa Bashir, Shabana Bibi, Muhammad Talha and Francislaine Aparecida dos Reis Livero
DOI: 10.2174/0109298673300632240823061848

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Research Article

Mitochondrial Dysfunction Associated with mtDNA Mutation: Mitochondrial Genome Editing in Atherosclerosis Research

Pp: 1568-1582
Author(s): Victoria A. Khotina*, Andrey Y. Vinokurov, Vasily V. Sinyov, Alexander D. Zhuravlev, Daniil Y. Popov, Vasily N. Sukhorukov, Igor A. Sobenin and Alexander N. Orekhov
DOI: 10.2174/0109298673323639240926095549

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Editorial

Mechanisms of Inflammation Chronification: Gene and Epigenetic Regulation of Intolerant Response (Trained Immunity)

Pp: 1583-1598
Author(s): Alexander Nikolaevich Orekhov*, Andrey Vladimirovich Omelchenko, Alexander Dmitrievich Zhuravlev, Andrey Yurievich Vinokurov, Natalia Vladimirovna Elizova, Vasily Vladimirovich Sinyov, Igor Alexandrovich Sobenin and Vasily Nikolaevich Sukhorukov
DOI: 10.2174/0109298673431092250819054506

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Commentary

Cells with Defective Mitophagy Do Not Accumulate Atherogenic LDL-Derived Cholesterol

Pp: 1599-1604
Author(s): Evgeny E. Borisov*, Volha I. Summerhill, Victoria A. Khotina, Anna M. Kosyreva, Tatiana I. Kovyanova, Vasily N. Sukhorukov and Alexander N. Orekhov*
DOI: 10.2174/0109298673294632250108102414

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Review Article

Binding Specificity and Local Frustration in Structure-based Drug Discovery

Pp: 1605-1615
Author(s): Zhiqiang Yan*, Yuqing Li, Ying Cao, Xuetao Tao, Jin Wang* and Yongsheng Jiang*
DOI: 10.2174/0109298673376099250428054846

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Review Article

Medical Artificial Intelligence: Opportunities and Challenges In Infectious Disease Management

Pp: 1616-1634
Author(s): Ankit Sahoo, Janhvi Singh, Kainat Alam, Nabil K. Alruwaili, Alhussain Aodah, Waleed H. Almalki, Salem Salman Almujri, Majed Alrobaian, Md Abul Barkat, Tanuja Singh, Jonathan A. Lal and Mahfoozur Rahman*
DOI: 10.2174/0109298673390868250728103906

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Research Article

Expression of TCEAL2 is a Novel Prognostic Biomarker and Potential Therapeutic Target in Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma

Pp: 1635-1650
Author(s): Jinyuan Li, Zhen Ye, Yuhong Gan, Dongbing Li* and Yibiao Chen*
DOI: 10.2174/0109298673371499250714133701

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Research Article

DDX59-AS1: A Novel Prognostic Biomarker and Immunotherapy Predictor in Lung Adenocarcinoma

Pp: 1651-1664
Author(s): Yanli Wang, Wei Li, Su Wei, Lixi Zhang, Dongbing Li and Xu Qi*
DOI: 10.2174/0109298673359149250212073143

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Research Article

LncRNA HYMAI Promotes Endothelial Cell Autophagy via miR-19a-3p/ ATG14 to Attenuate the Progression of Coronary Atherosclerotic Disease

Pp: 1665-1684
Author(s): Shao Ouyang, Zhi-Xiang Zhou, Hui-Ting Liu, Kun Zhou, Zhong Ren, Huan Liu, Qian Xu, Zhaoyue Wang, Wenhao Xiong, Gaofeng Zeng and Zhi-Sheng Jiang*
DOI: 10.2174/0109298673428431250917095939