Recent Patents on Anti-Cancer Drug Discovery

Volume 20, Issue 2

Mini-Review Article

Exosome-Derived Cargos in Immune Microenvironment in Esophageal Carcinoma: A Mini-Review

Pp: 137-144
Author(s): Yakun Zhang, Xiaoyan Sun, Yan Guan* and Ying Sun*
DOI: 10.2174/0115748928280161231123060159

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Research Article

Curcumin Inhibits the Growth of Hepatocellular Carcinoma via the MARCH1-mediated Modulation of JAK2/STAT3 Signaling

Pp: 145-157
Author(s): Jiaqi Su, Xianbing Liu, Xiaoyue Zhao, Hongjie Ma, Yuzhu Jiang, Xu Wang, Peiyuan Wang, Mingdong Zhao* and Xuemei Hu*
DOI: 10.2174/0115748928261490231124055059

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Research Article

Differentiation of Acute Leukemia Cells Including Cells with MLL-AF4 Rearrangements Induced by Jiyuan Oridonin A

Pp: 158-167
Author(s): Xueming Li, Fenglian Zhang, Yu Ke, Hongmin Liu, Zhenbo Hu* and Liuya Wei*
DOI: 10.2174/0115748928263141231204112640

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Research Article

Tyrosine Kinase Inhibitor Lenvatinib Causes Cardiotoxicity by Inducing Endoplasmic Reticulum Stress and Apoptosis through Activating ATF6, IRE1α and PERK Signaling Pathways

Pp: 168-184
Author(s): Siqi Wang, Fang Ji, Xiaoli Gao, Zhiyi Li, Si Lv, Juan Zhang, Jiarui Luo, Dan Li, Jie Yan, Huayang Zhang, Kaicheng Fang, Lin Wu and Miaoling Li*
DOI: 10.2174/0115748928265981231204044653

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Research Article

Comprehensive Analysis of Prognostic Alternative Splicing Signatures in Tumor Immune Infiltration in Bladder Cancer

Pp: 185-199
Author(s): Gao-Lei Liu, Hao Luo, Dan-Dan Liang, Li Zhong, Nan Dai* and Wei-Hua Lan*
DOI: 10.2174/0115748928329276241020184935

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Research Article

Ligustilide Inhibits the PI3K/AKT Signalling Pathway and Suppresses Cholangiocarcinoma Cell Proliferation, Migration, and Invasion

Pp: 200-212
Author(s): Yue Wu, Li Rong, Suifeng Zhang, Yuxi He, Na Song, Guoqing Zuo* and Zhechuan Mei*
DOI: 10.2174/0115748928332384240812060751

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Research Article

Metformin Inhibits NLRP3 Inflammasome Expression and Regulates Inflammatory Microenvironment to Delay the Progression of Colorectal Cancer

Pp: 213-222
Author(s): Gaojie Liu, Feixiang Wang, Yanlin Feng* and Hongsheng Tang*
DOI: 10.2174/0115748928274081240201060643

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Research Article

Matrine Enhances the Antitumor Efficacy of Chidamide in CTCL by Promoting Apoptosis

Pp: 223-231
Author(s): Xinglan He, Guanyu Wang, Yimeng Wang* and Chunlei Zhang*
DOI: 10.2174/0115748928289036240318040756

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Research Article

USP31 Activates the Wnt/β-catenin Signaling Pathway and Promotes Gastric Cancer Cell Proliferation, Invasion and Migration

Pp: 232-247
Author(s): Lan Li*, Limin Ye, Yinying Cui, Yueting Wu, Ling Shui, Zheng Zong and Zhao Nie
DOI: 10.2174/0115748928297343240425055552

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Research Article

The Emerging Role of ADAM 12 Regulates Epithelial-mesenchymal Transition by Activating the Wnt/β-catenin Signaling Pathway in Colorectal Cancer

Pp: 248-259
Author(s): Chengchen Huang*, Jian Wang, Jianqin Xiang, Chunrong Wu, Fan Wang, Jiangyan Chen, Guiyin Sun and Debing Xiang
DOI: 10.2174/0115748928305105240417101251

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Research Article

PDLIM1 Inhibits Chemoresistance by Blocking DNA Damage Repair in Gastric Cancer

Pp: 260-273
Author(s): Yuli Chen, Xin Yang and Qiang Li*
DOI: 10.2174/0115748928307544240502064448

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Review Article

Selinexor as a Therapeutic Target: Advances in Non-small Cell and Small Cell Lung Cancer Treatment Strategies

Pp: 274-284
Author(s): Bosheng Zheng, Wenqi Zhang, Shaonan Xie, Yaqing Han, Guangjie Liu, Yanjie Liu, Maogang Gao, Shize Wang and Qingyi Liu*
DOI: 10.2174/0115748928322627241016120142