Frontiers in Clinical Drug Research : Anti - infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The eighth volume of this series presents comprehensive reviews of interest to readers interested in the treatment of inflammatory diseases, new antiviral agents and strategies, specific antiprotozoal drugs that work against leishmania and helminths, and a study on potential agents against American foulbrood in honey bees. The 7 reviews included in this volume are: - Monoclonal antibodies as therapeutic agents for inflammatory diseases - Pharmacotherapy of emerging antiviral agents - Antiviral activity of vitamin D and COVID-19: current understanding - Anti-infectives to combat leishmaniasis - Anthelmintic drug discovery: current situation and future perspectives - Therapeutic targets for emerging Zika virus infection and vaccines in clinical trials - Agro-industrial waste: new source of raw material for the control of American foulbrood in honey bees

Frontiers in Clinical Drug Research – Anti Infectives (Volume 9) is a book series that provides updated reviews on the latest advancements in development of pharmaceutical agents for treating infectious diseases. The series covers various topics, including chemistry, pharmacology, molecular biology, and biochemistry of natural and synthetic drugs. Additionally, it addresses multi-drug resistance and pre-clinical/clinical findings on antibiotics, vaccines, antifungal agents, and antitubercular drugs. This series is an invaluable resource for pharmaceutical scientists and postgraduate students, offering critical information to support clinical trials and research in anti-infective drug discovery and epidemiology. The ninth volume presents five in-depth reviews, with topics including mature drugs and antivirals for COVID-19, bacteriocins as potent anti-infective agents, therapeutic interventions targeting free radicals in viral diseases, and a detailed exploration of natural anti-infective agents. The five reviews included in this volume are: - The role of mature drugs in the COVID-19 era - Antivirals to treat COVID-19 - Ribosomally synthesized bacteriocins as potent anti-infective agents - Therapeutic interventions against free radicals in viral diseases - A comprehensive overview of natural anti-infective agents

Human Papillomavirus Vaccination and Screening in the Elimination of HPV-Associated Cancers: Evidence Base from Randomized Trials explores cutting-edge strategies for eliminating HPV-associated cancers through vaccination and screening, showcasing findings from rigorous, evidence-based randomized trials. Key topics include the causative role of HPV in cancers, the effectiveness and safety of HPV vaccines, and the profound impact of gender-neutral vaccination programs. The book also covers innovative screening methods for vaccinated populations, addressing cervical and oropharyngeal cancers. Aimed at healthcare professionals, researchers, and students, this book provides crucial insights into the global efforts to combat HPV and its associated cancers. Key Features: - In-depth analysis of HPV`s role in cancer causation. - Comprehensive coverage of HPV vaccine efficacy and safety. - Evaluation of gender-neutral vaccination impact on public health. - Advanced screening methods for cervical and oropharyngeal cancers in vaccinated individuals. - Knowledge-driven recommendations for the future of HPV cancer prevention.

Concise Handbook of Epidemiology is an essential resource introducing readers to core principles, models, and research methods of modern epidemiology. This comprehensive guide covers foundational concepts like health and disease, disease occurrence, epidemiological models, and study designs. It also talks about disease surveillance, outbreak investigations, statistical methods, and advanced epidemiological techniques, including the impact of genomics and community-based epidemiology. Each chapter incorporates real-world case studies, offering readers practical insights and applications. Ethical considerations, innovative methods, and future directions in the field ensure readers are equipped with foundational knowledge and forward-looking perspectives. Key Features: - Foundational Overview: Covers health, disease occurrence, and key epidemiological frameworks. - Practical Tools: Offers research designs, statistical methods, and real-world case studies. - Advanced Topics: Explores genomics, statistical advances, and challenges in modern epidemiology. - Future Focus: Discusses ethics and evolving innovations shaping epidemiological practices.

Parasitic Diseases of Goats provides a comprehensive exploration of parasitic infections affecting goats and their impact on various organ systems. The book covers a wide range of parasitic diseases, including those affecting the gastrointestinal, respiratory, cardiovascular, nervous, and urogenital systems, as well as the liver, pancreas, skin, and musculoskeletal system. Diagnostic techniques and therapeutic approaches for managing these infections are also discussed in the chapters of this book. This book is an essential resource for veterinarians, researchers, students, and professionals in parasitology and veterinary medicine. Key features include detailed descriptions of parasite-related diseases, their pathogenesis, diagnostic methods, and treatment strategies to improve goat health and management.

This book provides a comprehensive exploration of vector-borne diseases, highlighting current trends, control strategies, and their public health implications. With contributions from experts, it informs readers about specific diseases caused by vectors such as mosquitoes and other zoonotic agents, presenting innovative approaches for prevention and management. The book begins with a focus on mosquito control strategies, emphasizing their significance in reducing the burden of vector-borne diseases. It further unravels the impact of Rickettsial infections, providing insights into these often-underdiagnosed diseases. Scrub typhus is explored through its co-infections with other vector-borne zoonotic diseases and analyzed using an integrated omics approach to better understand its pathogenesis and treatment. The final chapter sheds light on lymphatic filariasis, a neglected tropical disease, covering its endemic nature, clinical manifestations like elephantiasis and hydrocele, mass drug administration programs, and novel vector management techniques. This resource is ideal for public health professionals, researchers, and students, providing actionable insights into combating vector-borne diseases globally. Key Features: Discusses innovative mosquito control strategies and integrated vector management. Explores lesser-known diseases like scrub typhus and Rickettsial infections with advanced omics approaches. Provides a detailed analysis of lymphatic filariasis, including treatment strategies like antifilarial drugs and mass drug administration. Highlights the importance of public health interventions in combating neglected tropical diseases.

The book focuses on a new interdisciplinary understanding of the metabolic syndrome (MetS) for better health maintenance. It provides an updated understanding of the underlying principles, possible targets, implementation approaches and the effectiveness of various avoidance strategies in MetS. The chapters cover a wide range of topics, including major advances in general aspects of metabolic syndrome, functional changes, new diagnostic methods, genotype-phenotype associations, the effect of exercise and multitarget pharmacotherapeutic strategies for MetS and perspectives on personalized medicine. It also discusses epigenetic mechanisms underlying MetS-related processes and epigenetic strategies to prevent related diseases. The book also presents summarized information about the associated factors and mechanisms linking cancer and MetS and to identify potential targets for the treatment of these patients. A better understanding of the various linkages will provide greater insight into the management of cancer patients by preventing MetS and related alterations. Key Features - Comprehensive information focused on the biological factors and physiological changes associated with metabolic syndrome - Updates on metabolic syndrome diagnosis and management - Summarized information on clinical implications for cancer therapy - Thoroughly referenced chapters with summaries and discussions for quick understanding The book is an informative resource for interdisciplinary scientists and researchers in life sciences and medicine. Furthermore, it, including the insulin-like growth factor (IGF-1) pathway, estrogen signaling, visceral adiposity, hyperinsulinemia, hyperglycemia, aromatase activity, adipokinase production, angiogenesis, oxidative stress, DNA damage and pro-inflammatory cytokines, and their clinical implications in cancer therapy.

Common Ear Diseases in Dogs: Diagnosis and Management is an essential resource for veterinarians, veterinary students, and researchers focusing on ear health in dogs. This comprehensive guide covers the anatomy, physiology, microbiology, and pathology of canine ears, offering a thorough understanding of ear structure and function. It covers diagnosing, treating, and managing various ear conditions, including otitis externa, otitis media, aural hematomas, traumatic injuries, and more. Chapters explore cutting-edge diagnostic techniques, surgical interventions like ear canal ablation, and pain management strategies, making it a valuable tool for clinical practice. Written by subject matter experts, the book bridges foundational knowledge with advanced clinical applications, helping readers develop expertise in ear disease management. Key Features: - Provides an in-depth understanding of ear anatomy, physiology, and pathology in dogs. - Covers diagnosis, treatment, and management of common ear conditions, including infections, injuries, and neurological issues. - Features practical guides on advanced procedures like laser surgery and ear canal ablation.