Nanomedicine is a rapidly expanding field because of its benefits over conventional drug delivery technology, as it offers site-specific and target-oriented delivery of therapeutic agents. Nanoparticles and Nanocarriers Based Pharmaceutical Preparation presents a structured summary of recent advances and discoveries in nanomedicine and nanocarrier-based drug delivery. The book covers several key topics in a very simple and easy to understand language. Readers will be familiarized with many types of nanocarriers that have been developed over the past decade, the pharmaceutical formulations composed of organic and inorganic materials as well as their clinical benefits. Chapters are written with the help of authoritative sources of knowledge with the goal of building a foundational understanding of novel drug delivery systems. Since the subject matter is interdisciplinary, it will be of interest to students, teachers and researchers in a broad range of fields, including pharmaceutical sciences, nanotechnology, biomedical engineering and material sciences.

This e-book presents an overview of the different substances capable of modulating potassium channels in relation to various clinical indications in cardiology, pulmonology, endocrinology and neurology. The possible benefits and side effects of potassium channel modulators is discussed in correlation with biophysical and pharmacological properties of ion channels. Readers will learn how mutation of K+ channels can be conferred by molecular processes such as alternative splicing, RNA editing and posttranslational modifications. Altogether, this e-book will be of use to clinical practitioners, electrophysiologists and pharmacologists interested in the complicated but fascinating science of potassium channels.

Computer-Aided Drug Discovery Methods: A Brief Introduction explores the cutting-edge field at the intersection of computational science and medicinal chemistry. This comprehensive volume navigates from foundational concepts to advanced methodologies, illuminating how computational tools accelerate the discovery of new therapeutics. Beginning with an overview of drug discovery principles, the book explains topics such as pharmacophore modeling, molecular dynamics simulations, and molecular docking. It discusses the application of density functional theory and the role of artificial intelligence in therapeutic development, showcasing successful case studies and innovations in COVID-19 research. Ideal for undergraduate and graduate students, as well as researchers in academia and industry, this book serves as a vital resource in understanding the complex landscape of modern drug discovery. It emphasizes the synergy between computational methods and experimental validation, shaping the future of pharmaceutical sciences toward more effective and targeted therapies.

Novel Drug Delivery Systems (Part 2) covers the advanced techniques and innovations transforming pharmaceutical sciences, with a focus on enhancing drug efficacy and patient outcomes. This comprehensive guide explores a wide array of delivery methods, including nasopulmonary, transdermal, ocular, nanotechnology-based, implantable, and controlled-release injectables. Each chapter provides an in-depth analysis of these unique delivery routes, presenting both foundational knowledge and the latest technological advancements in the field. Designed for students, researchers, and professionals in pharmaceuticals and medicine, this book bridges basic concepts with cutting-edge practices, emphasizing the science and impact of controlled drug delivery. Key Features: - Detailed exploration of nasopulmonary, transdermal, ocular, and implantable delivery systems - Insight into nanotechnology's role in drug delivery - Comprehensive coverage of controlled-release injectables

This book provides an update on heterocyclic compounds that serve as key components of anti-cancer agents administered in pre-clinical settings. Many of the compounds highlighted in the book are being actively investigated for the bioactive properties against a range of cancer cell lines. There is potential for heterocyclic compounds to design agents that can target specific molecules to treat different types of cancers. Chapters are contributed by experts in pharmaceutical chemistry and are written to give a general overview of the topic to readers involved in all levels of research and decision-making in pharmaceutical chemistry and anti-cancer drug design. Part 1 of the book set covers these topics: - Heterocyclic anticancer compounds derived from natural sources with their mechanism of action - The role of terpenoids as anticancer compounds: an insight into prevention and treatment - Recent advances in synthesis and anticancer activity of benzothiazole hybrids as anticancer agents - Structure-activity relationship studies of novel hybrid quinoline and quinolone derivatives as anticancer agents - Tetrazoles: structure and activity relationship as anticancer agents - Progress in nitrogen and oxygen-based heterocyclic compounds for their anticancer activity: an update (2017-2020)

This book provides an update on heterocyclic compounds that serve as key components of anti-cancer agents administered in pre-clinical settings. Many of the compounds highlighted in the book are being actively investigated for the bioactive properties against a range of cancer cell lines. There is potential for heterocyclic compounds to design agents that can target specific molecules to treat different types of cancers. Chapters are contributed by experts in pharmaceutical chemistry and are written to give a general overview of the topic to readers involved in all levels of research and decision-making in pharmaceutical chemistry and anti-cancer drug design. Part II of the book set covers these topics: - Anticancer targets for heterocyclic lead compounds - Coumarin hybrids for cancer treatments - Progress in nitrogen and sulphur-based heterocyclic compounds for their anticancer activity - Imidazole as an anticancer heterocyclic ring - Morpholine for profiling anticancer lead compounds - Natural products as anticancer agents

Intellectual Property Rights Issues in Vaccine Development offers a timely exploration of the evolving role of intellectual property (IP) in shaping global vaccine research, innovation, and accessibility. As the world continues to grapple with public health challenges like the COVID-19 pandemic-this book provides a critical lens on how patents, trade secrets, and international agreements influence vaccine development and distribution. The contents of the book explore the historical evolution of IP in vaccinology, the debate over patent protection, the intersection of legal frameworks and ethical concerns, and the tension between innovation and equitable access. Special attention is given to global case studies, the impact of international agreements, and recommendations for stakeholders across policy, industry, and healthcare sectors. Key features: Traces the history and legal evolution of vaccine-related IP Analyzes global access challenges and equity concerns Explores the role of IP during the COVID-19 pandemic Examines real-world case studies of vaccine IP dynamics Offers actionable policy and industry recommendations

A fascinating exploration of widely used medicinal and culinary plants that straddle the line between healing and harm. Poison or Remedy? Case Reports on Selected Plants presents detailed botanical and phytochemical insights, highlighting the active compounds responsible for both therapeutic and toxic effects. The book draws on real-world cases from across the globe to examine how plant parts and preparations that are often used for health, culinary, or traditional purposes can lead to adverse outcomes when misused or misunderstood. Featured plants include celery and Heracleum species with phototoxic effects, cinnamon rich in coumarins, tropane alkaloid-containing Angel's Trumpet, colchicine-bearing Gloriosa and Colchicum, licorice, ivy, nutmeg, oleander, Syrian rue, rhododendron (mad honey), and the castor oil plant. Through these examples, the book underscores the delicate balance between medicinal potential and toxic risk. Key Features: - Explores the dual nature of medicinal plants through global case reports. - Presents phytochemical structures of key bioactive and toxic compounds. - Highlights real-world implications of plant misuse in food, medicine, and cosmetics. - Combines scientific accuracy with readability for both experts and general readers. - Promotes awareness of plant safety, regulation, and responsible usage.