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DOI: 10.2174/97898150798141220101 eISBN: 978-981-5079-81-4, 2022 ISBN: 978-981-5079-82-1
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For Books Asghar Ghasemi, Khosrow Kashfi, Zahra Bahadoran , " The Role of Nitric Oxide in Type 2 Diabetes ", Bentham Science Publishers (2022). https://doi.org/10.2174/97898150798141220101
Print ISBN978-981-5079-82-1
Online ISBN978-981-5079-81-4
Page: i-ii (2) Author: Eddie Weitzberg DOI: 10.2174/9789815079814122010001
Page: iii-vi (4) Author: Khosrow Kashfi, Asghar Ghasemi and Zahra Bahadoran DOI: 10.2174/9789815079814122010002
Page: vii-viii (2) Author: DOI: 10.2174/9789815079814122010003
Page: 1-26 (26) Author: Asghar Ghasemi* and Khosrow Kashfi DOI: 10.2174/9789815079814122010004 PDF Price: $30
Page: 27-38 (12) Author: Asghar Ghasemi* and Khosrow Kashfi DOI: 10.2174/9789815079814122010005 PDF Price: $30
Page: 39-66 (28) Author: Zahra Bahadoran, Mattias Carlström, Parvin Mirmiran and Asghar Ghasemi* DOI: 10.2174/9789815079814122010006 PDF Price: $30
Page: 67-86 (20) Author: Zahra Bahadoran, Mattias Carlström, Parvin Mirmiran and Asghar Ghasemi* DOI: 10.2174/9789815079814122010007 PDF Price: $30
Page: 87-106 (20) Author: Zahra Bahadoran, Pedro González-Muniesa, Parvin Mirmiran and Asghar Ghasemi* DOI: 10.2174/9789815079814122010008 PDF Price: $30
Page: 107-127 (21) Author: Zahra Bahadoran, Parvin Mirmiran, Mattias Carlström and Asghar Ghasemi* DOI: 10.2174/9789815079814122010009 PDF Price: $30
Page: 128-160 (33) Author: Hamideh Afzali, Tara Ranjbar, Khosrow Kashfi and Asghar Ghasemi* DOI: 10.2174/9789815079814122010010 PDF Price: $30
Page: 161-189 (29) Author: Nasibeh Yousefzadeh, Sajad Jeddi, Khosrow Kashfi and Asghar Ghasemi* DOI: 10.2174/9789815079814122010011 PDF Price: $30
Page: 190-209 (20) Author: Zahra Bahadoran, Parvin Mirmiran, Khosrow Kashfi and Asghar Ghasemi* DOI: 10.2174/9789815079814122010012 PDF Price: $30
Page: 210-237 (28) Author: Tara Ranjbar, Jennifer L. O’Connor and Khosrow Kashfi* DOI: 10.2174/9789815079814122010013 PDF Price: $30
Page: 238-259 (22) Author: Zhe Pei, Kuo-Chieh Lee, Amber Khan and Hoau-Yan Wang* DOI: 10.2174/9789815079814122010014 PDF Price: $30
Page: 260-283 (24) Author: Parvin Mirmiran, Zahra Bahadoran, Khosrow Kashfi and Asghar Ghasemi* DOI: 10.2174/9789815079814122010015 PDF Price: $30
Page: 284-302 (19) Author: Parvin Mirmiran, Zahra Bahadoran, Khosrow Kashfi and Asghar Ghasemi* DOI: 10.2174/9789815079814122010016 PDF Price: $30
Page: 303-323 (21) Author: Zahra Bahadoran, Parvin Mirmiran, Khosrow Kashfi and Asghar Ghasemi* DOI: 10.2174/9789815079814122010017 PDF Price: $30
Page: 324-349 (26) Author: Zahra Bahadoran, Parvin Mirmiran, Mehrnoosh Bahmani and Asghar Ghasemi* DOI: 10.2174/9789815079814122010018 PDF Price: $30
Page: 350-365 (16) Author: DOI: 10.2174/9789815079814122010019
Type 2 diabetes (T2D) is a complex metabolic disorder characterized by impaired glucose metabolism and pancreatic β-cell dysfunction. No effective treatments are available for T2D, although there have been many developments in the therapeutic arena. Nitric oxide (NO) is an endocrine agent with multiple and important biological roles in most mammalian tissues. NO has emerged as a central regulator of energy metabolism and body composition. NO bioavailability is decreased in T2D. Several of the pharmaceuticals used in T2D affect the NO system and perhaps even more so by the drugs we use to treat diabetic cardiovascular complications. Experimental works in animal models of T2D show promising results with interventions aimed to increase NO signaling. However, translation into human studies has so far been less successful, but more large-scale prolonged studies are clearly needed to understand its role. This book is a collection of reviews that deal with the role of nitric oxide in type 2 diabetes, providing a unique overview of NO signaling, and pointing out key areas for more detailed research. The book includes contributions about the pathophysiology of T2D, a brief history of discovery and timeline of NO research, a comprehensive overview of impaired NO metabolism in T2D, precursors of NO (i.e., L-arginine, L-citrulline, nitrate, nitrites, and NO donors), NO and T2D from genetic points of view, NO and diabetic wound healing, NO and osteoporosis, NO and hyperuricemia, NO and Alzheimer's Disease, therapeutic applications of NO and NO donors in T2D. The compilation is of great value to anyone interested in the biochemistry of NO and its relationship to diabetes.
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