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DOI: 10.2174/97816810834761160101 eISBN: 978-1-68108-347-6, 2016 ISBN: 978-1-68108-348-3
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For Books Takanori Kawaguchi , " Cancer Metastasis and Cancer Stem Cell/Niche ", Bentham Science Publishers (2016). https://doi.org/10.2174/97816810834761160101
Print ISBN978-1-68108-348-3
Online ISBN978-1-68108-347-6
Page: i-ii (2) Author: Julio Aguirre-Ghiso DOI: 10.2174/9781681083476116010001
Page: iii-iii (1) Author: Takanori Kawaguchi DOI: 10.2174/9781681083476116010002
Page: iv-iv (1) Author: Takanori Kawaguchi DOI: 10.2174/9781681083476116010003
Page: v-vi (2) Author: Takanori Kawaguchi DOI: 10.2174/9781681083476116010004
Page: 3-23 (21) Author: Eric D. Young, Linheng Li, Fariba Behbod and Danny R. Welch DOI: 10.2174/9781681083476116010005 PDF Price: $15
Page: 24-60 (37) Author: Reiji Kannagi, Bi-He Cai, Hsiang-Chi Huang and Keiichiro Sakuma DOI: 10.2174/9781681083476116010006 PDF Price: $15
Page: 61-73 (13) Author: Kyoko Hida, Nako Maishi, Dorcas A. Annan and Yasuhiro Hida DOI: 10.2174/9781681083476116010007 PDF Price: $15
Page: 74-108 (35) Author: Takeshi Tomita, Atsuko Deguchi and Yoshiro Maru DOI: 10.2174/9781681083476116010008 PDF Price: $15
Page: 109-133 (25) Author: Shoji Nakamori and Koji Morimoto DOI: 10.2174/9781681083476116010009 PDF Price: $15
Page: 134-145 (12) Author: Takanori Kawaguchi DOI: 10.2174/9781681083476116010010
A malignant tumor is an actively growing tissue, composed of cells derived from a single cell line that has undergone irreversible differentiation. These cells are invasive and also metastasize in the body, resulting in malignant cancer. Recent research suggests that a malignant tumor originates from cancer stem cells (CSC) accompanied with physiological niches. Cancer Metastasis and Stem Cell/Niche explains the invasiveness and metastasis of cancer cells I the light of information gained from the CSC / niche theory. Five chapters present a review on the fundamental relationships between CSCs, their niche and metastasis, the regulation of cell surface glycan expression in CSCs, tumor endothelial cells and metastasis, toll-like receptor 4 (TLR4)-mediated premetastatic microenvironment, and in surgical cancer metastasis. This monograph is intended as a primary reference on CSC research for physiologists, clinical oncologists, stem cell researchers and molecular biologists.
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