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DOI: 10.2174/97816810819911160101 eISBN: 978-1-68108-199-1, 2016 ISBN: 978-1-68108-200-4
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For Books Nahum Rosenberg , " Mesenchymal Cell Activation by Biomechanical Stimulation and its Clinical Prospects ", Bentham Science Publishers (2016). https://doi.org/10.2174/97816810819911160101
Print ISBN978-1-68108-200-4
Online ISBN978-1-68108-199-1
Page: i-i (1) Author: Michael Soudry DOI: 10.2174/9781681081991116010001
Page: iii-iii (1) Author: Nahum Rosenberg DOI: 10.2174/9781681081991116010002
Page: v-v (1) Author: Nahum Rosenberg DOI: 10.2174/9781681081991116010003
Page: 3-12 (10) Author: Eyal Ginesin, Kamal Hamoud and Nahum Rosenberg DOI: 10.2174/9781681081991116010004 PDF Price: $15
Page: 13-22 (10) Author: Nahum Rosenberg and Reuben Haber DOI: 10.2174/9781681081991116010005 PDF Price: $15
Page: 23-34 (12) Author: David Nikomarov and Nahum Rosenberg DOI: 10.2174/9781681081991116010006 PDF Price: $15
Page: 35-48 (14) Author: Yaron Har-Shai, Isaac Zilinsky, Rei Ogawa and Chenyu Huang DOI: 10.2174/9781681081991116010007 PDF Price: $15
Page: 49-57 (9) Author: Yaron Berkovich, Jacob Shapira and Nahum Rosenberg DOI: 10.2174/9781681081991116010008 PDF Price: $15
Page: 59-64 (6) Author: Marwan Haddad, Jacob Shapira and Nahum Rosenberg DOI: 10.2174/9781681081991116010009 PDF Price: $15
Page: 65-72 (8) Author: Yoav Leiser and Adi Rachmiel DOI: 10.2174/9781681081991116010010 PDF Price: $15
Page: 73-75 (3) Author: Nahum Rosenberg DOI: 10.2174/9781681081991116010011
The electrical response of cells to mechanical stimulus is known as mechanotransduction. This monograph is a summary of the mechanotransduction in musculoskeletal cells responsible for body tissue maintenance, support, cover and movement. While mechanotransduction is similar among these cells, there are also several important differences in mechanical parameters and cellular pathways characteristic to each cell type. Therefore, readers will have the opportunity to update their knowledge about the increasing volume of information on mechanotransduction in these cells gained from current research. The book features a primer on general aspects of cellular biomechanics and the experimental methods and equipment commonly used for investigating cellular mechanotransduction in vitro in two dimensional cultures in which cells are adherent to plastic surfaces. Characteristic mechanotransduction pathways in mesenchymal stem cells (MSCs), chondrocytes, osteoblasts and fibroblasts are described in the accompanying chapters. Finally, a description of clinical implementation of mechanical stimulation is presented with emphasis on distraction osteogenesis, involving osteoblast stimulation, and skin stretching techniques based on fibroblast stimulation. This monograph is a useful reference for readers involved in graduate courses or basic research in cell biology and musculoskeletal physiology.
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