Polarity Index in Proteins-A Bioinformatics Tool

Pathogenic Bacteria

Author(s): Carlos Polanco

Pp: 36-49 (14)

DOI: 10.2174/9781681082691116010010

* (Excluding Mailing and Handling)


This chapter includes the identification of a group of peptides known as antimicrobial peptides. They have an important role in the immune system of all living organisms. The identification of the main function associated to each peptide was made by calculating the polar profile of the peptide with the QSAR method called polarity index, already described in Sect. 3.3. The peptides computationally tested were taken from two different databases: Antimicrobial Peptides Database (APD2), and Uniprot Database, which included the set of peptides called selective cationic amphipatic antibacterial peptides.

Keywords: Antibacterial peptides, Antimicrobial peptides, Antrax, Immune system, Gram staining, Serial computing, Listeriosis, Living organisms, Matrix ΣQi-1Qi, Selective cationic amphipatic antibacterial peptides.

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