Frontiers in Medicinal Chemistry

Volume: 8

Calixarenes in Biotechnology and Bio-Medical Research

Author(s): Roman V. Rodik, Vyacheslav I. Boyko and Vitaly I. Kalchenko

Pp: 206-301 (96)

DOI: 10.2174/9781681081755116080008

* (Excluding Mailing and Handling)


Application of calixarene derivatives in biotechnology and bio-medical researches is reviewed in this article. Results on antiviral, bactericidal, antithrombothic, antituberculosis, anticancer activities of modified calixarenes are presented. Transfection ability, specific protein complexation, enzyme mimic, membranotropic properties and toxicity of modified calixarenes are described.

Keywords: Alkaline phosphatase, anticancer, anticoagulant and antithrombotic, antituberculosis activity, antiviral, bactericidal, calixarenes, chloride channel, enzyme mimic, fungicidal, magnetic resonance imaging, protein complexation, protein tyrosine phosphatase, sodium-potassium pump, toxicity, transfection.

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