Inositol & its Phosphates: Basic Science to Practical Applications

Mechanisms of Biological Actions of Inositol and InsP6 II: DNA Damage Repair

Author(s): A.K.M. Shamsuddin and Guang-Yu Yang

Pp: 243-251 (9)

DOI: 10.2174/9781681080079115010021

* (Excluding Mailing and Handling)

Abstract

DNA damage is one of the earliest changes in cancer formation. Within the cell and the nucleus, inositol and its phosphates are found wherein they are involved in DNA damage repair machinery, chromatin remodeling, RNA editing and mRNA transport.


Keywords: Chromatin remodeling, mRNA transport, nuclear pore, NHEJ, NPC, RNA editing, RNA interference.

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