The concept of emergence is absent from classical molecular biology for it is
implicitly, or explicitly, assumed that all the properties of living systems are in fine carried
out by specific macromolecules. The concept of biological system implies that a number of
biological properties are not borne by specific macromolecules but by a system of
macromolecules. In this perspective a biological property originates from the connections
between molecules belonging to a system. In classical molecular biology a property does
not emerge for it is carried by a specific macromolecule. In systems biology properties
emerge from the interactions that take place between the elements of a system.
Keywords: Information of biological systems, Joint probability, Boltzmann
statistics, Allostery, Induced fit, Information and induced fit, Information and
ambiguity, Information and departure from thermodynamic equilibrium,
Functions of connection, Generalized microscopic reversibility.
