Polymeric Nanomedicines

Dendrimers: A New Tool for Drug Administration

Author(s): Constantin V. Uglea and Marcel Popa

Pp: 233-250 (18)

DOI: 10.2174/9781608054848113010009

* (Excluding Mailing and Handling)

Abstract

This chapter provides a brief description of the synthesis, biological evaluation, and biomedical applications of dendrimers especially in dendrimer-mediated cancer therapy in the last decade with an emphasis on the development and use of dendrimers in cancer therapeutics.


Keywords: Dendrimers, initiator core, oligoarginine, PAMAM dendrimers, linker, HPMA, PEG, LHRH, PEGylated dendrimers, nanomedicines, nanoparticulate systems, micribicides, gene carriers, non-viral gene delivery systems, biomedical imaging.

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