In this chapter, three different drugs are resumed. Antihistamines are widely
used in dermatological conditions to ameliorate pruritus and to inhibit the histamine
release. Dapsone has been used for almost 50 years in the treatment of several infectious
diseases including, leprosy and malaria and recently in the treatment of pneumocystic
carinii pneumonia in patients with AIDS. Dapsone also has anti-inflammatory
properties and has been used in dermatology and rheumatology. The development of the
synthetic antimalarials and their use in the treatment of cutaneous diseases have been
well described. Chloroquine is a 4-aminoquinoline antimalarial used in the treatment
and prophylaxis of malaria. It has also been used in the treatment of hepatic amoebiasis,
lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Keywords: Histamine antagonists, histamine H1 antagonists, histamine H1
antagonists, sedating, histamine H1 antagonists, non-sedating, dapsone, sulfones,
antimlarials, antirheumatic agents, aminoquinolines, skin and connective tissue
diseases, skin.
