In today’s fast-moving era of technology and science, nanotechnology has
massive potential in treating various neurological disorders, particularly those caused
by metals, such as Parkinson's disease, Alzheimer's disease, and multiple sclerosis.
These disorders are often accompanied by the accumulation or dysregulation of metals
(e.g., aluminum, copper, iron, etc.) or metal-based toxic substances in the human brain,
which can lead to neurotoxicity and neurodegeneration. The exceptional properties of
nanomaterials, such as elevated surface area, improved reactivity, and their ability to
traverse biological barriers, make them promising candidates for targeted therapeutic
interventions. This chapter investigates the potential applications of nanotechnology in
reducing the neurotoxic effects of metals. Here, some feasible future interventions
using nanotechnology to provide novel strategies for early-stage diagnosis,
personalized treatments, and long-term management of metal-related neurological
disorders will be discussed. The incorporation of nanotechnology into clinical practice
holds great promise for considerably improving patient outcomes and advancing the
field of neurotherapeutics.
Keywords: Metal nanoparticles, Nanomaterials, Nanomedicine, Nanoparticle drug delivery, Nanotechnology, Neurological disorders, Neurotoxicity.
