Unravelling Alzheimer’s: Innovations in Pathogenesis, Diagnosis, and Therapeutics

Digital Tools and Artificial Intelligence in Alzheimer’s diagnosis

Author(s): Shubh Deep Yadav, Shubhanshu Goel, Ayushi Tyagi* and Khushboo Bansal

Pp: 112-140 (29)

DOI: 10.2174/9798898814953126010008

* (Excluding Mailing and Handling)

Abstract

The integration of digital tools and Artificial Intelligence (AI) has brought significant advancements to the diagnosis of various diseases, particularly neurodegenerative disorders like Alzheimer’s disease. AI, particularly Machine Learning (ML), enables the analysis of vast and complex datasets, such as neuroimaging, electronic health records, cognitive assessments, and biomarkers, which are crucial for early detection and accurate diagnosis. These technologies offer the potential to identify subtle changes in patients' conditions over time, improving the precision of diagnosis and facilitating the development of personalized treatment plans. Digital tools, including wearable devices, mobile applications, and fitness trackers, allow for continuous and passive monitoring of patient data, providing real-time insights into physiological parameters like gait, heart rate, and brain activity. These tools can detect early signs of cognitive decline and other abnormalities, aiding clinicians in making more informed decisions about disease progression. AI has demonstrated its potential in automating image analysis, identifying biomarkers, and predicting disease progression, which can expedite the diagnostic process and enhance the overall healthcare experience. Additionally, AI-driven models can integrate data from multiple sources, enabling comprehensive assessments and more accurate predictions about the onset and development of diseases like AD. However, there are several challenges associated with the widespread adoption of AI in clinical settings, such as concerns about data quality, model interpretability, ethical considerations, and cost. Overcoming these barriers is essential to ensuring that AI technologies become accessible, reliable, and effective in healthcare. This chapter explores the transformative potential of AI and digital tools in diagnostics, discussing their applications, benefits, challenges, and the future directions for improving patient care and outcomes. 


Keywords: Alzheimer’s disease, Artificial Intelligence, Biomarkers, Digital tools, Early diagnosis, Machine Learning, Neuroimaging.