This chapter covers the foundations of diabetes technology, discussing
important topics like disease mechanisms, causes, risk factors, and associated
complications. An urgent need for advancements in diabetes technology is emphasized
so that it can reduce the complications associated with diabetes and enhance the
lifestyle of affected individuals with preventive healthcare. It further discusses the
classes of molecules and the genetic-level analysis of drug-receptor interactions, along
with the role of receptors and drugs in detail. The kinetics of insulin with receptors are
investigated, ranging from short-acting to ultra-long-acting insulin. There is a thorough
discussion of in silico modeling, the effects of genetic variants on drug-receptor
interactions, and the main medications used to treat diabetes. The chapter concludes
with a discussion of the different risk factors and how they affect the management of
diabetes. As a result, this chapter provides a solid research basis for both the present
and upcoming areas of diabetes technology.
Keywords: Computational, Complications, Disease mechanism, Drug-receptor, In silico, Risk factors.