Autoimmune Disorders and Secondary Plant Metabolites (Part 2)

Plant Secondary Metabolites: Therapeutic Potential and Pharmacological Properties in Psoriasis

Author(s): Simranjeet Kaur, Akshita Arora, Tuhin James Paul, Dilpreet Singh and Amandeep Singh *

Pp: 1-27 (27)

DOI: 10.2174/9798898812799125010004

* (Excluding Mailing and Handling)

Abstract

 Psoriasis, an autoimmune skin condition characterized by inflammation and excessive cell growth, necessitates ongoing treatment due to its recurrent nature. Conventional therapies often involve synthetic drugs, which are associated with some severe side effects. Recent research highlights the potential of herbal medicines as safer and more effective alternatives. This chapter explores the potential of natural remedies like Dysidea avara, Tripterygium wilfordii, curcuma longa, Strobilanthes Cusia, Capsicum annum., Polygonum cuspidatum, Ligusticum chuanxiong, and Thymus vulgaris, which offer promising and safe alternatives for psoriasis management. The phytoconstituents obtained from these herbal plants exhibit anti-inflammatory, immunomodulatory, and anti-oxidant properties that could help modulate the immune response and reduce skin inflammation. This chapter focuses on the utilization of medicines in psoriasis treatment, highlighting their enhanced therapeutic profiles and reduced toxicity. 


Keywords: Anti-psoriatic activity, Mode of action, Phytoconstituents, Plant secondary metabolites, Psoriasis, Skin inflammation.