Advanced Liposome Technologies: Preparation, Mechanisms, and Applications

Medical and Nonmedical Applications of Liposomes

Author(s): Chandra Has *

Pp: 398-480 (83)

DOI: 10.2174/9798898813338125010016

* (Excluding Mailing and Handling)

Abstract

This chapter investigates the several uses of liposomes, from medicine to nonmedical fields. Liposomes are important drug delivery methods in medicine because they improve therapeutic efficacy, reduce adverse effects, and allow for tailored drug release. Their uses in cancer therapy, vaccine administration, and antimicrobial therapies are particularly emphasized. The chapter discusses the mechanics of liposome drug loading, including active and passive loading strategies and parameters such as liposome size, surface charge, and lipid composition that impact their effectiveness. It also dives into ways to measure drug encapsulation efficiency and loading capacity, emphasizing sophisticated techniques like ion gradient methods and transition metal complexation. Beyond medicine, liposomes are utilised in cosmetics, food, textiles, and agriculture to regulate the release of active chemicals, improve product efficacy, and increase sustainability. In research, liposomes are used as model membranes to examine biological processes. The chapter also discusses the importance of liposomes in scientific developments such as biosensors, diagnostic imaging, and nutraceuticals, demonstrating their wide range of uses.


Keywords: Liposomes, drug delivery, cancer therapy, vaccine delivery, antimicrobial treatments, drug encapsulation, biosensors, controlled release, encapsulation efficiency, nonmedical applications.