The primary purpose of this introductory chapter is to provide a brief
overview of the origin of liposomes, the progress in research, and different preparation methods, their characteristics, the mechanism behind their formation, and their
diverse applications. Liposomes have received a lot of attention not just for their role
in bioactives (drugs and biomolecules) transport, but also as model membranes for
biophysical and biological research, making them valuable tools in scientific studies.
It is important to have a foundational understanding of the field of liposomal research
before exploring its details. This approach ensures that readers can interrelate the
various individual topics effectively. A basic knowledge of liposome technology is
essential for understanding the various applications and advancements in the field. By
starting with an introduction to the history and development of liposomes, readers will
appreciate the evolution of this technology and the milestones achieved over the years.
Discussing the preparation methods will highlight the technological advancements
and the innovative approaches developed. Understanding the characteristics and mechanisms of liposome formation will provide insights into their functionality and the
science behind their numerous applications. The chapter also briefly highlights emerging trends such as artificial intelligence (AI)-assisted formulation design, marking a
shift toward predictive and data-driven liposome engineering. This comprehensive
overview sets the stage for a deeper exploration of specific topics in liposomal research
and technology.
Keywords: Liposome technology, targeted delivery, phospholipid bilayers, controlled release, bioavailability, drug delivery, nanocarriers.