Advanced Liposome Technologies: Preparation, Mechanisms, and Applications

Introduction

Author(s): Chandra Has *

Pp: 1-19 (19)

DOI: 10.2174/9798898813338125010005

* (Excluding Mailing and Handling)

Abstract

The primary purpose of this introductory chapter is to provide a brief overview of the origin of liposomes, the progress in research, and different preparation methods, their characteristics, the mechanism behind their formation, and their diverse applications. Liposomes have received a lot of attention not just for their role in bioactives (drugs and biomolecules) transport, but also as model membranes for biophysical and biological research, making them valuable tools in scientific studies. It is important to have a foundational understanding of the field of liposomal research before exploring its details. This approach ensures that readers can interrelate the various individual topics effectively. A basic knowledge of liposome technology is essential for understanding the various applications and advancements in the field. By starting with an introduction to the history and development of liposomes, readers will appreciate the evolution of this technology and the milestones achieved over the years. Discussing the preparation methods will highlight the technological advancements and the innovative approaches developed. Understanding the characteristics and mechanisms of liposome formation will provide insights into their functionality and the science behind their numerous applications. The chapter also briefly highlights emerging trends such as artificial intelligence (AI)-assisted formulation design, marking a shift toward predictive and data-driven liposome engineering. This comprehensive overview sets the stage for a deeper exploration of specific topics in liposomal research and technology. 


Keywords: Liposome technology, targeted delivery, phospholipid bilayers, controlled release, bioavailability, drug delivery, nanocarriers.