The Role of Asymmetric Synthesis in Drug Discovery

Chemistry of Biologically Active Chiral Oxazine Derivatives

Author(s): Taruna Yadav, Rajni Sharma and G. B. Dharma Rao *

Pp: 120-141 (22)

DOI: 10.2174/9798898812676125010009

* (Excluding Mailing and Handling)

Abstract

The utilization of naturally abundant resources is becoming more and more essential in the pursuit of green chemistry and sustainable development. Over the past two decades, the synthesis of organic compounds has increased interest in C-H functionalization. In organic chemistry, oxazine core unit molecules are renowned for their biological and synthetic significance along with numerous properties, such as ease of use, low cost, relative repeatability, stable products, and the absence of hazardous chemicals, high temperatures, pressures, or energies. The greener synthesis of oxazines is a step ahead of the preceding methodologies. In this book chapter, up-to-date improvements and novel trends in the green alternative synthesis of asymmetric oxazine have been highlighted and examined.


Keywords: Asymmetric synthesis, Asymmetric catalyst, Eco-friendly, Oxazine, Sustainable, Synthetic strategies.

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