The utilization of naturally abundant resources is becoming more and more
essential in the pursuit of green chemistry and sustainable development. Over the past
two decades, the synthesis of organic compounds has increased interest in C-H
functionalization. In organic chemistry, oxazine core unit molecules are renowned for
their biological and synthetic significance along with numerous properties, such as ease
of use, low cost, relative repeatability, stable products, and the absence of hazardous
chemicals, high temperatures, pressures, or energies. The greener synthesis of oxazines
is a step ahead of the preceding methodologies. In this book chapter, up-to-date
improvements and novel trends in the green alternative synthesis of asymmetric
oxazine have been highlighted and examined.
Keywords: Asymmetric synthesis, Asymmetric catalyst, Eco-friendly, Oxazine, Sustainable, Synthetic strategies.