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Author(s): Gazanfar Rahmathulla, Michael A. Vogelbaum
Pp: 107-110 (4)
DOI: 10.2174/978160805132811001010107
* (Excluding Mailing and Handling)
Malignant gliomas are optimally managed with maximal surgical resection followed by radiation and chemotherapy. Drug delivery challenges and chemoresistance limits the efficacy of standard chemotherapeutic agents. Understanding glioma biology has led to the development of a variety newer molecular targeting agents which have begun to show exciting preliminary results. Bevacizumab (Avastin) is one such drug likely to play a key role in malignant glioma therapy. We review the current literature in regard to the use of bevacizumab and its adverse effects in neurosurgical patients.
Cite this chapter as:
Neurosurgical Implications of Avastin, Controversies in Neuro-Oncology Avastin and Malignant Gliomas (2010) 1: 107. https://doi.org/10.2174/978160805132811001010107
DOIhttps://doi.org/10.2174/978160805132811001010107 Print ISSN2210-5565
Publisher NameBentham Science Publisher
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