The dysfunctional gonadotropin secretion and other features of PCOS like
Insulin Resistance (IR), chronic inflammatory state, and hyperandrogenism have a
significant impact on reproductive and gestational outcomes. Women with PCOS have
reduced ability to conceive owing to poor oocyte quality, ovulatory dysfunction,
implantation failure, and uterine abnormalities. Besides, if the conception stage is
crossed, these subjects are at a graded risk of carrying the pregnancy to term and
developing various issues like recurrent pregnancy loss, preterm labour, gestational
diabetes, and hypertension. This chapter summarises the mechanistic insights into
various pregnancy complications and management strategies among PCOS women.
Having background knowledge of what and how will help us not only in preparing the
optimal management of these women but also put physicians in a position to use preconception counseling as a tool in the armamentarium of prevention of complications
of pregnancy and enhance clinical outcomes.
Keywords: Body mass index, Fetal growth abnormalities, Gestational diabetes mellitus, Polycystic ovarian syndrome, Pre-conception counseling, Recurrent pregnancy loss.
