Apart from the well-known presentations of anovulation, infertility,
hirsutism, acne, and hyperandrogenism, women with PCOS are not only at risk for
metabolic complications but may have comorbidities such as thyroid disorders and
sleep disturbances, especially obstructive sleep apnea. The incidence of
hypothyroidism, especially subclinical hypothyroidism, is common in PCOS, which
may interfere with the treatment outcomes, especially for anovulation. Similarly,
obstructive sleep apnea is also more common and may be responsible for the worsening
of the associated metabolic disorders and interferes with treatment for inducing
ovulation. Therefore, in the management of PCOS, one must be aware of the potential
comorbidities, which must be identified in a timely manner and properly managed.
Keywords: Anovulation, Autoimmune thyroid disease, Excessive daytime sleepiness, Hypothyroidism, Obesity, Snoring, Subclinical hypothyroidism.
