Bariatric surgical interventions have emerged as a promising therapeutic
option for PCOS patients struggling with severe obesity. Bariatric surgery encompasses
various procedures like gastric bypass, sleeve gastrectomy, and gastric banding aimed
at promoting weight loss by altering the anatomy of the gastrointestinal tract. Beyond
weight reduction, these surgeries exert profound metabolic effects, including improved
insulin sensitivity and hormonal balance, which are pivotal in managing PCOS.
However, bariatric surgery is not without risks and should be considered in the context
of individual patient needs and medical history. Close monitoring and multidisciplinary
care are essential post-surgery to ensure optimal outcomes and long-term success. This
chapter provides an overview of bariatric surgical interventions as a promising avenue
for managing PCOS in severely obese patients, addressing both weight-related issues
and underlying metabolic dysregulation. Additionally, the potential implications of
bariatric on reproductive aspects are briefly addressed.
Keywords: Bariatric surgery, Homocysteine, Inflammation, Insulin resistance, Laparoscopic sleeve gastrectomy, Lipid peroxidation, Obesity, Rouxen-Y gastric bypass, Type 2 diabetes mellitus.
