The pathogenesis of Polycystic Ovary Syndrome (PCOS) is mostly
dependent on adipocyte malfunction, which contributes to the syndrome's diverse
metabolic and reproductive symptoms. The main cells of adipose tissue, called
adipocytes, are not just passive energy stores; they are also active endocrine organs that
secrete a variety of adipokines, hormones, and inflammatory mediators that regulate
metabolism. Adipose tissue inflammation, insulin resistance, and dysregulated
adipokine production are all signs of adipocyte dysfunction in PCOS, which
exacerbates the metabolic abnormalities that are typical of the condition.
Keywords: Adipocytes, Adipose dysfunction, Adipsin, Adiponectin.
