Clinical presentation of PCOS varies among individuals. A patient with
Polycystic Ovary Syndrome (PCOS) may present to the gynecologist with menstrual
irregularities, mainly oligo-amenorrhea, by means of detected polycystic morphology
on ultrasonography. A patient might also seek a dermatologist for hyperandrogenic
manifestations, such as acne, hirsutism, androgenic alopecia, and acanthosis nigricans,
or a fertility clinic with complains of infertility. Patients may arrive at the obesity clinic
with metabolic abnormalities. Understanding the clinical features at presentation is
crucial for understanding the disease and conducting a thorough assessment of the
patient. Therefore, in this chapter, we will learn in detail about the assessment of all the
clinical features of PCOS in detail. Since PCOS is the diagnosis of exclusion, clinical
features differentiating PCOS from other conditions with overlapping symptoms like
non-classical congenital adrenal hyperplasia, hypo-hyperthyroidism, hyperprolactinemia, Cushing syndrome, acromegaly, and ovarian and adrenal neoplasm will
also be discussed.
Keywords: Acne, Adults, Adolescents, Alopecia, Clinical presentation, Diabetes mellitus, Ferriman Gallwey score, Hyperandrogenism, Hirsutism, Hyperandrogenaemia, Insulin resistance, Infertility, Lean polycystic ovary syndrome, Menstrual irregularities, Obese polycystic ovary syndrome, Oligomenorrhea, Polymenorrhea, Polycystic ovarian morphology, Phenotype.
