Biopolymers have become apparent as a potential therapeutic material,
which shows an important role in treating different diseases like cancer, neurological
disorders, cardiovascular disorders, infectious diseases, diabetes, and drug delivery.
Due to its biocompatible and biodegradable properties, it is widely used for therapeutic
purposes. This chapter provides detailed information regarding the pharmacokinetic
and pharmacodynamic properties of biopolymers. It involves a comprehensive analysis
of how these materials are involved in drug absorption, distribution, metabolism,
excretion, and their interaction with physiological systems. The pharmacokinetic
properties of biopolymers depend on various factors such as molecular weight,
degradation behavior, and structure of biopolymers, which are important for
therapeutic efficacy. On the other hand, pharmacodynamic properties provide detailed
information regarding mechanisms like cellular uptake and internalization, modulation
in immunological responses, and physical and chemical interactions by which these
materials show therapeutic responses by targeting specific cells or tissues, extending
beyond the target consequences, and receptor-associated interactions. Recent
advancements in the field of biopolymers involve their utilization for specific
therapeutic effects, enhancing patient compliance and outcomes, with various
mechanisms of action involved for showing therapeutic responses by biopolymers
mentioned in this chapter. By gathering information regarding biopolymers'
pharmacokinetic and pharmacodynamic properties, this chapter aims to provide
detailed information on various mechanisms involving the effectiveness and efficacy of
biopolymer-based therapeutics in clinical utilization.
Keywords: Applications, Biopolymers, Mechanism of action, Pharmacodynamics, Pharmacokinetics.
