Herbal Nanotherapy for Diabetes

Herbal Nano Therapy: Mechanism of Action

Author(s): Rohini Kharwade, Nikhil Hatwar and Nilesh Mahajan *

Pp: 112-143 (32)

DOI: 10.2174/9798898811082125010008

* (Excluding Mailing and Handling)

Abstract

The life-threatening ability of certain diseases including cancer, diabetes, asthma, stroke, heart disease, and others received more attention in modern medicinal advancement. To enhance the solubility, bioavailability, controlled release, and dose reduction of medications, greater attention is given to creating innovative formulations for drug delivery. However, resistance toward conventional synthetic drugs with their toxicity and side effects has sparked demand for herbal medicine. Therefore, herbal medicines are more prone to integrate into nanocarriers as compared to synthetic medicines because of their fewer adverse effects and better therapeutic efficacy. Herbal nano therapy includes nanocarriers containing herbal drug extract, phytoconstituents, and bioactive or biomarker constituents. The phytoconstituent-loaded nanocarrier proposed novel formulations with controlled and targeted drug delivery of herbal components and instantaneously increased their therapeutic efficacy. Herbal nanomedicine is safe concerning diagnostic and therapeutic aspects. The synthesis of herbal nanomedicine, its mechanism, and characterization by various analytical techniques have significant advances in the future impact of nanotechnology on smart herbal medicine.


Keywords: Ayush, Ayurveda, Bhasma, Characterization, Coacervation method, Ethosomes, Functionalized nanocarriers, Green synthesis, Herbal nanomedicines, Herbal therapy, High-pressure homogenization, Metallic nanoparticles.