Herbal Nanotherapy for Diabetes

Introduction to Herbal Nano Therapy: Understanding the Science

Author(s): Prashant Upadhyay*, Shipra Sharma, Reetika Rawat, Tapasvi Gupta, Durga Prasad, Divya Sharma, Sukirti Upadhyay and Arti Gupta

Pp: 1-27 (27)

DOI: 10.2174/9798898811082125010004

* (Excluding Mailing and Handling)

Abstract

Herbal medicines have served humanity for numerous generations all across the world. Current methods in phytochemical and phytopharmacological sciences base the clinical applicability of numerous medicinal plants on the composition of active compounds and how much of these compounds are present in samples. Numerous therapeutic compounds such as flavonoids, tannins along terpenoids exist as watersoluble substances yet they have limited potential for absorption. Multiple barriers prevent these compounds from penetrating cell membranes or taking absorption or crossing cell membrane barriers because of their large molecular size and poor absorption and inability to cross cell membranes. This causes them to have low bioavailability and reduced efficacy. Plant extracts fail to enter clinical practice due to these circumscribing factors. Researchers have extensively recommended using nanotechnology to overcome the obstacles related to herbal medicine delivery. Nanoscale technology increases the efficacy of plant extracts by reducing the amount of administration required while reducing side effects and producing therapeutic advantages. Nanocarriers maintain active components at their best concentrations during therapy while guiding them to specific destinations. Treatment methods that exist in the conservative healthcare system typically do not achieve these standards. This section evaluates both nanotechnology principles and their use in herbal drug delivery systems. The drug delivery system using herbal nanotechnology remains essential for diabetes management because polymeric and lipid nanoparticles, liposomes, dendrimers, and niosomes show superior performance than traditional oral hypoglycaemic agent treatments. 


Keywords: Diabetes mellitus, Herbal nanocarrier system, Liposomes, Polymeric nanoparticles, Solid lipid nanoparticles.