All genetic variations are the outcome of mutations in the genetic material.
The greater the mutation ratio, the greater will be the genomic diversity. Currently,
epigenomics enables us to locate, read, and translate the epigenetic mechanism that
monitors and reins the whole genome of coronaviruses at different stages. Many
researchers reported the role of epigenetic mutations in the development and
progression of several common viral infections, especially age-related diseases. Many
families of viruses can counter the immune response by utilizing a cascade of
epigenetic events and taking over the regulatory capacity for their benefit.
Coronaviruses possess the same mechanism to affect epigenetic machinery, i.e., by
improving mutations in the epigenetic code, DNA methylation, post-translational
alterations of histone proteins and other proteins linked with epigenome, or direct
dysregulation of enzymes.
Keywords: Epigenetic mutations, Enzyme dysregulation, DNA methylation, Post-translational alterations.
