Metabolic syndrome (MetS) indicates a cluster of symptoms that include
abdominal obesity, dyslipidemia, hypertension, and hyperglycemia. Even though the
etiology of MetS is unknown, it is thought to be multifaceted, with a complicated
interaction between genetic predisposition and significant changes in lifestyle behavior,
such as physical inactivity, high carbohydrate diets, and alcohol and cigarette use. The
circadian system regulates many physiological and behavioral rhythms, which operate
on 24-hour cycles. Circadian rhythm disturbances are also seen in various clinical
disorders linked to adipose tissue functioning. In addition, night-shift employees who
have their rest-activity cycles reversed are more likely to acquire MetS. Individuals
with MetS experienced more seasonal variations in mood and behavior, with obesity
being a substantial risk factor for metabolic syndrome. MetS has been linked to
psychiatric illnesses. In those diagnosed with major depressive disorder and bipolar
disorder in adulthood, disruption to biological rhythms (sleep, social activities, and
eating habits) has been linked to essential components of MetS. MetS and its
components were found to be connected to a higher risk of suicide. It is apparent that
the relationship between behavior and MetS is bidirectional, and each component can
affect the other. Awareness of MetS-related factors can aid in identifying high-risk
individuals and implementing disease prevention and control strategies, as well as
lifestyle adjustments. Lifestyle modification can help to improve the MetS condition
and behavior.
Keywords: Behavior, MetS, Metabolic syndrome, Microbiota, Psychiatric illness, Stress.
