Andrographis (Acanthaceae) is a genus of 26 species native to India, mainly
used for the treatment of snake bites, diabetes, fever, cholera, dysentery, gonorrhea,
and malaria. Medicinal properties of Andrographis are attributed to the presence of
phytochemicals such as andrographolide, neoandrographolide, 14-deoxy-11,-
2-didehydroandrographolide, 14-deoxy andrographolide, isoandrographolide, 14-deoxy
andrographolide 19 β-Dglucoside, homoandrographolide, andrographan, andrographosterin, and stigmasterol. Nanotechnology is a technique capable of achieving a high
degree of precision in functions. By creating eco-friendly materials that can be applied
to nanomedicine, plants have mediated the synthesis and fabrication of materials in
nanotechnology. Mostly, silver nanoparticles biosynthesized using Andrographis
species showed significant pharmacological activities viz ., antimicrobial, antioxidant,
anti-inflammatory, antidiabetic, mosquito larvicidal, hepatocurative, and anticancer
activity.
Keywords: Andrographolide, Andrographis species, Phyto-nanotechnology, Medicinal plants, Pharmacological activities.