Multiple sclerosis (MS) is an autoimmune disease that causes myelination
defects and axonal impairment in the central nervous (CNS) system, causing inhibition
of electrical transmission. The disease's typical symptoms include stiffness, persistent
discomfort, exhaustion, motor and mobility problems, and cognitive deficits. Although
immunosuppressive and immune-modulating medications have been the fundamental
basis of MS treatment, there is currently no known treatment for the disease. Herbaloriginated therapies are now being considered a possible therapeutic option for MS by
using medicinal plant extracts or phytochemicals. Numerous research works have
emphasized the medicinal herbs' anti-inflammatory and antioxidant properties, which
make them a natural treatment for MS. According to the literature, several plants, such
as hemp, turmeric, ginkgo, St. John's wort, black cumin, ginseng, and ginger have been
reported to have various therapeutic effects in MS patients. Otherwise, the most
promising substances that have been suggested to treat MS symptoms include
curcumin, resveratrol, cannabinoids, apigenin, omega 3, and vitamin D. In this chapter,
we compiled medicinal plants, and phytochemicals that have potential effects on MS. It
is suggested that clinical trials were conducted on MS patients with medicinal plants,
which were prominent in vivo findings. We also advise further research in this field to
identify the precise active ingredients present in these extracts for the best composition
necessary for the intended therapeutic effect.
Keywords: Herbal remedy, Multiple sclerosis (MS), Natural product, Neurodegenerative diseases.
