Anticancer Drugs Sourced from Marine Life

Marine Biota-based Anticancer Drug Candidates in Pipeline

Author(s): Ramasamy Santhanam*, Santhanam Ramesh*, Subbiah Balasundari* and Sheba R. David *

Pp: 20-45 (26)

DOI: 10.2174/9789815256055124010005

* (Excluding Mailing and Handling)

Abstract

This chapter deals with the approved and marketed anticancer drugs derived from marine sponges, mollusks/cyanobacteria, and tunicates; marine biota-derived anticancer compounds in clinical trials i.e in III, II, and I phases; and bioactive new chemical entities (NCEs) with anticancer function from marine biota. Limiting factors in the development and approval of drugs from marine biota and significant challenges in the development and approval of marine drugs are also given.


Keywords: Challenges in drug development, Clinical trials, Marine anticancer drugs, New chemical entities, Limiting factors.

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