Owing to the low cost, fast response, easy miniaturization, portable
instrumentation, and multiple analyte detection capabilities, electrochemical sensors
stand out in the realm of sensing and thus occupy a prominent place in analytical
supramolecular chemistry. Over the past several decades, the recognition of
biologically and environmentally vital analytes via electrochemical responses (increase
or decrease in current density), has attracted much attention from supramolecular
chemists. The fabrication of electrochemical sensors through a competitive sensing
phenomenon known as indicator displacement assay (IDA) has made them more
realistic for target analyte detection. In this chapter, besides discussing various types
and techniques of electrochemical sensors, we envisioned discussing diverse IDAbased electrochemical sensors for saccharides, biomarkers, neurotransmitters, and
various other analytes. The authors are of the viewpoint that this chapter will meet the
needs of the researchers working on the design, fabrication, and application of IDAbased electrochemical sensors.
Keywords: Analyte, Biomarker, Current density, Detection, Electrochemical sensor, Guest, Host, Indicator displacement assay, Indicators, Macrocycle, Recognition, Signal, Signal modulation, Teceptors.