Anticancer Immunity: Reviewing the Potential of Probiotics

Prebiotics and Postbiotics for Anticancer Immunity

Author(s): Gireesh Kumar Singh*, Ravi Bhushan Singh and Anshul Shakya

Pp: 221-243 (23)

DOI: 10.2174/9789815165135123040012

* (Excluding Mailing and Handling)


 Cancer remains a daunting task for clinicians and scientists. Many scientists across the globe are toiling in their labs to find an effective and safe treatment modality for cancer. Although significant stride has been achieved in the field of cancer treatment, and millions of precious lives have been saved using available therapeutic strategies, viz. chemotherapy, radiation therapy, biologics and surgical intervention. However, the search for the panacea for cancer is still not over, and new dimensions are being constantly explored. Maneuvering the immune system for controlling and treating cancer is a new fascinating field, and rigorous researches are underway. The importance of anticancer immunity as a promising treatment approach has been recognised even by the Nobel Prize Authority and James P. Allison and Tasuku Honjo were jointly awarded the 2018 Nobel Prize in Physiology or Medicine for their revolutionary research in cancer immunotherapy. This chapter discusses the different aspects of immune system response vis a vis cancer development and strategies to manipulate the immune system through prebiotics and postbiotics to control and cure the different types of cancer. Prebiotics and postbiotics are being explored extensively for their role in modifying disease progression and control of cancer. Prebiotics and postbiotics are considered safe alternatives to manipulate the immune system in order to get therapeutic benefits for cancer. 

Keywords: Anticancer immunity, Antigens, Antibody, Immune check points, Immune surveillance, Immunotherapy, Lymphocytes, Prebiotics, Postbiotics.

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